Thermoflexus hugenholtzii: KNN16_01995
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Entry
KNN16_01995 CDS
T07254
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
thug
Thermoflexus hugenholtzii
Pathway
thug00300
Lysine biosynthesis
thug00550
Peptidoglycan biosynthesis
thug01100
Metabolic pathways
thug01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
thug00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
KNN16_01995
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
KNN16_01995
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
KNN16_01995
Enzymes [BR:
thug01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
KNN16_01995
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QWK11060
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Position
415819..417258
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AA seq
479 aa
AA seq
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MAENSGIRVAVQGMTLADLAEALSGRRPPWEIPIRHVSIDSRVCGEGDVFIALPGERTDG
HRYVGDAFQRGAIAALVHQEVSEGAMQVDLERGPWPESLELPVCFRVSRTLEALHRWAGW
WRARFPVRVIGITGSVGKTSTKELTWAVLSRRYETLKSEGNLNSEIGLPLMLLRLTPRHQ
RAVLEMGMYARGEIAALCAIARPIVGVVTMVGPVHLERLGSMEAIAAAKAELVEALPEDG
VAVLNRDDPYVREMAGRTRARVFFYGLDPEADLWADEIVSEGLEGIRFDLHYRGETFRRV
RVSLLGRHSVHTALRAIAVGILEGLTWDEIFAGLRDPRAQLRLVAVPGLNGSILLDDTYN
ASPPSMLAALNLLAELEGRKIAVLGDMLELGAYEVEGHRLVGGRAGTVVDLLITVGPRAR
IIAREAMAVGLPADRVWVCDSNAEAIEILRRILKPGDVVLVKGSRGLRMEEIVNALCEG
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
atggcggagaacagcggaatacgtgtggcggttcaggggatgaccctggcggatctggcg
gaggccctgagcgggcggcgtcctccctgggagatcccgatccgccatgtgtccatcgac
tcccgggtctgcggggagggggatgtgttcatcgccctgccgggggagcggaccgacggc
catcgctatgtcggggacgccttccagcgcggggcgatcgccgccctggtccatcaggag
gtgtccgagggggcgatgcaggtggacctggagcgagggccctggccggagtccctggag
ctcccggtgtgctttcgggtctcgcggaccctggaggccctccaccggtgggcgggatgg
tggcgggcgcgcttcccggtgcgggtgatcgggatcacggggagcgtggggaagaccagc
acgaaggagctgacctgggctgtgctctcccggcgttatgagacgttgaagagcgaaggg
aacttaaacagcgagatcggcctgcccctgatgttgctccggctgacgccgcgccatcag
cgggcggtgctggagatggggatgtatgcgcggggggagatcgcggccctttgcgccatc
gcccgccccatcgtgggcgtggtcaccatggtgggcccggtccacctggagcgcctgggg
agcatggaggccatcgcggcggccaaggccgagctggtggaggccctgcccgaggatggg
gtagccgtcctcaatcgggacgatccttacgtgcgggagatggcggggcggacccgggcg
cgggtgttcttttacgggctggatccggaggcggacctgtgggcggatgagatcgtgagc
gaagggctggaggggatccgcttcgatcttcattatcggggagagaccttccggcgggtg
cgggtctccctgctgggccggcacagcgtgcacaccgccctgcgggcgatcgccgtgggg
atcctggaggggttgacctgggatgagatcttcgccggcctgcgggacccgcgggcgcag
ttgcgcctggtggcggtgcccgggctgaacggttcgatcctcctggacgacacttacaat
gccagcccgccgtcgatgctggccgcgctgaacctgctggctgagctggagggccgcaag
atcgcggtgctgggggacatgctggagctgggggcgtatgaggtcgagggacaccggctg
gtgggcgggcgagcggggacggtggtggacctcctgatcaccgtggggcctcgggcgcgc
atcatcgcccgggaggcgatggcggtaggcctgccggcggaccgggtgtgggtctgcgac
tcgaacgccgaggccatcgagatcctccgccgcatcctgaagcccggcgatgtggtcctg
gtgaagggctcccggggcctgcgcatggaggagatcgtgaacgccctgtgtgagggatga
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