Thermococcus sp. P6: A3L12_03160
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Entry
A3L12_03160 CDS
T05739
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
thy
Thermococcus sp. P6
Pathway
thy00230
Purine metabolism
thy01100
Metabolic pathways
thy01110
Biosynthesis of secondary metabolites
Module
thy_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
thy00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
A3L12_03160
Enzymes [BR:
thy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
A3L12_03160
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Gene cluster
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Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
Gly_transporter
Motif
Other DBs
NCBI-ProteinID:
ASJ10367
UniProt:
A0A218PC16
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Position
590093..592222
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AA seq
709 aa
AA seq
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MFPHEERIIRERLGREPNGIEKAMLEVMWSEHASYKSSRRWLKLLPTKNEHVILGPGEDA
GVVRFDENTAIVVGIESHNHPSAVEPYGGAATGVGGIVRDILCMGARPVALLDSIRFGPI
DGERNRYLLEGVVKGISDYGNRIGVPTVGGEAEFDESLEGYTLVNVACVGLMKPEDLVHS
YVTEAGLKLVLVGNRTGRDGIHGVTFASEELSENEEDRSAVQIPDPFTEKLLIEATLEAL
KTGKIKALKDLGGGGLTCASSEMAGKKGFGAIIYADRVPQREPSMNAVEVMISESQERML
FAVREEDLEEIAKIFEKYGLEWAVVGEITEEPRFVVYWGDERVADLPVELLVEVPTIEWE
AEPYTLERDVKTPDVSIEEALLKVLSSPNVISKRWIWEQYDHEVQGRTVLKPGLDAAVLK
INDEYGLAVVSDSNPSYSHLNPYHGAMGTVAEVVRNLVSVGARPLALVDNLNFASPERPH
VYWSFTETVKGLRDAARVFGLAYVSGNVSFYNEINGRPIKPTPVVAGLGKVRLERIMTMD
FKEEGDLIGIVGLTRRELGGSELYRVLGVERGIAPRVDPEREREKAGGILKAIELGLVKA
VHDVSRGGIAVALTEMAVSGNLGFEVEIARIPTEGKMDPLEVLFSESHGRFLITFEEENL
KEIGELFGEFAVIGRVGGKRLVFRNFEEVSIDLKKAGELYESFPELLGE
NT seq
2130 nt
NT seq
+upstream
nt +downstream
nt
gtgtttcctcatgaggagaggatcatcagggaaaggctcggaagggagcccaacgggatt
gaaaaagccatgctcgaggttatgtggagcgagcacgcctcctacaagtcgagcaggcgc
tggttaaagctccttccaacaaaaaacgagcacgtaatcctaggtccgggtgaggatgcc
ggtgttgtgaggttcgacgagaacaccgctatagtggtcggaatagagagccacaaccac
ccttcggccgtggagccctacggtggggccgcaacgggcgtgggcggaatagtgagggac
atcctctgcatgggcgctcgtccagtagcgttactggattcgatacgcttcgggccgatt
gacggggagcgcaacaggtacctgctcgagggggttgtgaagggcatatccgactacggg
aacagaataggcgtcccgacggttgggggggaagcggagttcgatgagagccttgagggt
tacacgctcgtgaacgtggcgtgcgttggactgatgaagcccgaagacctcgtccacagc
tacgttactgaggccgggctcaagctggtcctcgtcggcaacaggacgggaagggacgga
atccatggggttacgttcgcgagcgaggagctgagcgaaaacgaagaggaccgctccgcg
gtgcagattccggaccccttcacggagaagcttttaattgaggcaacccttgaagcgctc
aagaccggaaagattaaggctctaaaggacctcggcggcggcggtttgacctgcgcttcc
tcggagatggctggaaagaagggctttggggctataatttatgctgatagggttccccaa
agagagcccagcatgaacgccgtggaggtcatgatctcggagagtcaggagaggatgctc
tttgcagtcagggaggaggatctggaagagatagcgaagatctttgagaagtacgggctc
gaatgggccgtggtgggtgaaataacagaggagccacgcttcgtcgtttactggggcgac
gagagggttgcggacctgccggtagaacttctggtggaggttcccacgatagaatgggag
gccgagccttacaccctcgaaagggacgtaaaaactccggacgtaagcatcgaggaagcc
ctccttaaggtgctctcaagtccgaacgtaattagcaagcgctggatctgggagcagtac
gaccacgaggttcaggggagaacggtgttaaagcccggcctcgacgcggcggtgcttaaa
ataaacgacgaatacggactggcggttgtgagcgacagcaatccctcctacagccacctt
aacccctaccatggagcgatggggacggttgctgaagtcgttagaaacctcgtcagcgtt
ggggcgagacctctggcgctggtggacaacctcaacttcgcgtctccagaaaggccccat
gtttactggagctttacggagacggttaaaggtcttagggatgccgcgagggtttttgga
ctggcttacgtgagcggaaacgtgagtttctacaacgagatcaacggcagacccataaaa
cccactcccgtcgttgcgggccttggaaaggtgaggctcgagcgcatcatgaccatggac
ttcaaggaagagggagatctgataggcatcgtcggactaacgagaagggaacttggaggg
agcgagctttacagggttctgggggttgaaaggggcatagctccgagggttgacccggag
agggaaagggaaaaagccgggggcattttaaaggccatagagctcgggctggtgaaggcc
gttcacgacgttagcaggggtggaattgcagtggcactgacggagatggcggtaagcggg
aacctcgggttcgaggtcgagatagccagaatcccgacggaggggaagatggacccgctg
gaggtactcttttcagagagccatgggcggttcctgataacctttgaggaggaaaacctc
aaggagatcggggaactctttggggagtttgccgtcattggaagggtcggaggcaaaagg
ctcgttttcagaaacttcgaggaggtttccatagacctaaaaaaggccggggagctctac
gagtcatttccagagcttctcggggagtga
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