Thermotomaculum hydrothermale: TTHT_0628
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Entry
TTHT_0628 CDS
T06993
Symbol
topA
Name
(GenBank) DNA topoisomerase I
KO
K03168
DNA topoisomerase I [EC:
5.6.2.1
]
Organism
thyd
Thermotomaculum hydrothermale
Brite
KEGG Orthology (KO) [BR:
thyd00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
thyd03032
]
TTHT_0628 (topA)
03400 DNA repair and recombination proteins [BR:
thyd03400
]
TTHT_0628 (topA)
Enzymes [BR:
thyd01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
TTHT_0628 (topA)
DNA replication proteins [BR:
thyd03032
]
Prokaryotic type
DNA Topoisomerases
TTHT_0628 (topA)
DNA repair and recombination proteins [BR:
thyd03400
]
Prokaryotic type
DSBR (double strand breaks repair)
NHEJ (non-homologous end-joining)
SHIIR (short-homology-independent illegitimate recombination)
Facilitator
TTHT_0628 (topA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Topoisom_bac
Zn_ribbon_Top1
Toprim
DUF1272
Toprim_4
Zn_ribbon_3
Auto_anti-p27
DNA_ligase_ZBD
ATP12
Toprim_2
Zn_ribbon_recom
Motif
Other DBs
NCBI-ProteinID:
BBB32206
UniProt:
A0A7R6SY55
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Position
645700..647982
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AA seq
760 aa
AA seq
DB search
MADKLIIVESPAKSRTIEKYLKGKYHVEATMGHIVDLPKKEFGIDIENGFKPKYVVIDEK
KKVVSNLKKKAKNYSEIYLAADPDREGEAICYHLKNLLSSKDKKIYRVLFNEITPTGISK
ALESPGDVDLNKFNAQQTRRIVDRIVGYKVSPLLWEKVKRGLSAGRVQTVALRIICEREE
EIRKFNKEEYWTILAELLKNEIPFTAKLVEIDGRKVRIGNKKAPIAIDSKQLAEQIKREL
EKGNFLIESVKKKHKKRNPLPPFITSKLQQEAARVLDFPVKKTMRIAQKLYEGVDIGDGP
VGLITYMRTDSTRISKEAIESARAFIGEKFGKEELPSKPNVYSAKENAQDAHEAIRPTSV
FRTPESISKYLSKDELALYSLIWKRFVASQMTPAIFEETEVKIKNGKYTLEASGTVLKKE
GFLKVYNPGVGKDKLLPEVEEGEKLALKNIEAKQNFTTPPPRYTEATLVKELESNGIGRP
STYATIISVIQNRAYVLMKEKKFYPTALGELVNKLLVSSFPKIFEINYTANLEKELDGIE
EGKLDYLEVLRKFYIEFERYLKRAEEEMVSVKRNGVPIGEKCEKCGGEMVKKVGKFGVFI
ACSNYPECKNTREVVESADGEDANGEKKTCPKCGGELVLKSGRYGKFYTCSNYPECDYRE
SLNGNGNGVKQLDKNCPQCGKPLVERKGKYGKFIACSGYPECKYIEKEKPKELDIICPKC
GKGKIVVRKTRRGKVFYGCSRYPDCDYASWTLPDNGEKSD
NT seq
2283 nt
NT seq
+upstream
nt +downstream
nt
atggcagataaacttataattgttgaatctcctgcaaaatcaagaacaatcgaaaaatat
cttaaaggcaaataccatgtggaagccacaatggggcatattgttgatttgccaaaaaaa
gaatttggcatagacatagaaaacggttttaagccaaagtatgttgttattgatgagaag
aaaaaggttgtttccaatctgaaaaaaaaggcaaagaattactcggaaatttaccttgct
gccgaccctgatagagagggtgaagctatctgttatcatttgaagaatctcctttcatct
aaagacaaaaagatatacagggttttgtttaatgaaataacccccacaggaatatcaaag
gctttagaatcccctggagatgttgatttaaacaaatttaatgcacaacagacaagaagg
attgtggatagaattgttggttataaggtttccccacttttatgggaaaaggtaaagagg
ggattgtctgcaggtagggttcagacagttgctttaaggattatctgcgaaagggaagaa
gagataaggaaattcaacaaagaagagtactggacaatattggcagaattattaaaaaat
gaaatcccttttactgcaaaactcgttgagatagacgggagaaaggttagaatagggaat
aaaaaggcgccaatcgcaatagactctaaacaacttgccgaacaaattaagagggaactt
gaaaaaggaaattttttaatagaatcagttaagaaaaagcataaaaaaaggaatccattg
ccaccttttattacaagtaaattacagcaggaagcagcaagggttttagattttcctgtt
aagaaaacaatgagaatagcgcagaaattgtatgaaggtgttgatataggtgatggccct
gtcggtttgattacatatatgagaacagactctaccagaatttcaaaagaggctattgaa
agtgcaagggcttttattggcgaaaaattcgggaaggaagaattaccgtcaaaaccaaat
gtatattctgcaaaggagaatgcacaggatgcacacgaggctataagacctacatctgtt
tttagaacaccggaatctatttcaaaatacctctctaaagatgagctggcactatatagc
cttatctggaaaagatttgtagcaagccagatgacacctgcaatatttgaagaaacagag
gtaaaaattaagaacggaaagtatacccttgaagcaagtggcactgttttaaaaaaagag
gggtttttaaaggtttacaacccaggggtagggaaagacaaattgttaccagaggttgaa
gagggggaaaaacttgcattgaaaaatatagaagcaaagcaaaactttacaaccccaccg
ccaaggtacaccgaggcaacccttgttaaagaacttgaatcaaacggaataggaaggcct
tccacctatgcaacaataatatctgttattcaaaacagggcttatgtgttaatgaaggag
aaaaagttttacccaactgccttaggtgaactggtaaacaagttgcttgtttcctctttt
cccaaaatatttgaaattaattacactgcaaaccttgagaaagagttagacggtattgaa
gaaggcaaacttgattaccttgaagttttaagaaagttttacatagagtttgagaggtac
ttaaaaagagcagaagaggaaatggtaagcgttaagagaaacggtgtgcctattggggaa
aagtgtgaaaagtgtggtggcgaaatggtaaaaaaggttggaaaatttggagttttcatt
gcctgttccaactatcctgagtgcaaaaatacccgtgaggttgttgaaagtgcagatgga
gaagatgcaaatggtgagaaaaaaacttgcccaaaatgtggaggtgagcttgttttaaaa
tcaggtaggtatggaaagttttatacctgttcaaattatcctgaatgcgattacagggaa
tccttaaacggtaacggaaacggagtaaagcagcttgacaaaaactgtccccagtgtggg
aagcctcttgttgagagaaaagggaaatacggtaagtttatagcgtgctcaggttatcct
gaatgtaaatatatagaaaaagaaaaaccaaaagaactggatataatttgtcctaagtgt
ggaaagggaaaaattgttgtgagaaaaacgagaagaggaaaggttttttacggctgttca
aggtatccggattgtgattacgcatcatggactttgcctgataatggtgagaagtctgac
taa
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