Thermotomaculum hydrothermale: TTHT_1285
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Entry
TTHT_1285 CDS
T06993
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
thyd
Thermotomaculum hydrothermale
Pathway
thyd00300
Lysine biosynthesis
thyd00550
Peptidoglycan biosynthesis
thyd01100
Metabolic pathways
thyd01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
thyd00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
TTHT_1285 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TTHT_1285 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TTHT_1285 (murF)
Enzymes [BR:
thyd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
TTHT_1285 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Kdo_hydroxy
Motif
Other DBs
NCBI-ProteinID:
BBB32802
UniProt:
A0A7R6PUA6
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Position
complement(1345242..1346612)
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AA seq
456 aa
AA seq
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MKVSEFAKLIGKEAYNFKEREIKGFSIDTRTIKEGEMFIAIKTDRDDGHRFIEDAKRKGA
CSYLLSYKRRSIDLDAFENLFFVGDTVQTIQKAAKNLVSKKVSDSVAITGSAGKTTTKEL
TYHIFKSYFKTRSTLGNFNNTLGLPLSILNTVDEKIDYFIAELGMSYKGEIKRLIDILNP
NIRVWLNVYPAHIGNFGSIEEVRDAKAEILLNQDPDTVIVYNYDDILVKSKVDRAIGVKY
SFGKADGADLKIKKCETGLNSSILVLEFEGKDIVLKSSLVGDFNCYNIAASVLTALLANV
SIEKIKESVESFVPLENRGRFVIKDRILLYNDCYNSNPEALKRIISHFSSVEHKGRKVAI
IGDMLELGGFSEEMHREIGKLLNKSDFDLIITWGKDARFINSEVEGKAKFHFEKNINVAE
EINNIVKEGDLIIVKASRGMKGEVIIDEIIKKWGEK
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
atgaaagtaagtgaatttgcaaagttaataggaaaagaagcctacaatttcaaagaaaga
gagattaagggattttcaatagacacaaggactattaaagaaggagaaatgtttatagct
attaaaacagatagagacgatggccataggtttattgaggatgccaaaagaaaaggagca
tgttcttatcttttaagctacaagagaagaagtatagatttagacgcatttgaaaattta
ttttttgttggagatacggttcaaacaatacagaaagctgcaaaaaaccttgtatcaaag
aaggtttctgatagtgttgcaattacagggagtgcaggaaaaacaacaaccaaagaactt
acataccacattttcaaatcatactttaaaacaaggtcaacattaggaaacttcaacaac
acattaggcttgcccctttctatattaaatactgttgatgaaaagattgactattttata
gcagaattgggaatgagctataagggagaaattaaaagacttattgatattttaaatcca
aatataagggtatggctaaatgtatatcctgcgcatataggaaattttggtagcatagaa
gaggttagagacgctaaggctgagattcttcttaatcaggaccccgatacagttattgtt
tataactatgatgacatacttgtaaaaagtaaggttgatagggcaataggagtaaaatac
tcgtttggaaaggcagatggcgctgatttaaaaataaaaaagtgtgagacagggcttaat
agttctattttggttttggagtttgaaggaaaggatattgttttgaaatcctcacttgtg
ggagattttaactgttacaacattgcggcatctgttctaacagcattacttgctaatgtc
tcgattgaaaaaataaaggagagtgtcgaatcatttgttccacttgaaaatagagggaga
tttgttataaaagatagaattttgttgtacaacgattgctataattcaaatcctgaggca
ttaaaaagaattattagtcatttttcttctgttgagcataaaggaaggaaggtcgcaata
ataggggatatgttagagttaggcggtttttctgaggagatgcatagagaaataggcaaa
ttgttaaataagagtgattttgatttaataatcacatggggaaaggacgcaagatttata
aacagcgaagttgagggaaaagcaaaattccactttgagaagaatataaatgttgctgaa
gagattaataatattgttaaagagggagatttaattattgtaaaagcatcaaggggtatg
aaaggtgaagtaataattgatgaaattattaaaaaatggggagaaaaatga
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