KEGG   Thermotomaculum hydrothermale: TTHT_2224
Entry
TTHT_2224         CDS       T06993                                 
Symbol
purH
Name
(GenBank) phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
thyd  Thermotomaculum hydrothermale
Pathway
thyd00230  Purine metabolism
thyd00670  One carbon pool by folate
thyd01100  Metabolic pathways
thyd01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:thyd00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    TTHT_2224 (purH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    TTHT_2224 (purH)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:thyd04147]
    TTHT_2224 (purH)
Enzymes [BR:thyd01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     TTHT_2224 (purH)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     TTHT_2224 (purH)
Exosome [BR:thyd04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   TTHT_2224 (purH)
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS CoA_binding_2 IpaB_EvcA
Other DBs
NCBI-ProteinID: BBB33648
UniProt: A0A7R6PH49
LinkDB
Position
2294153..2295688
AA seq 511 aa
MKRYALISVSDKNGIVDFAKKLENLGFEIVSSGGTFKVLKDAGLNPVKVSDITGFPEILD
GRVKTLHPKIHGGILVDMRKESHREELKKHGINNFEIVCVNLYPFKETVKKTDDVDEIIE
NIDIGGPTLLRASAKNFYSVAVVVDPDDYSKVVEEIEKNGEVSLDTRKKLALKALSHTAS
YDIAISSFFNRMLENKFPERLFLEYNLENTLRYGENPHQQAAFYSEPDFRNDELPALKKL
QGKELSYNNLMDSDAAIEMVREFDEPACVIVKHANPCGIGRDNESLKIAFERAHSTDPMS
AFGGIIALNREVDGELASLITKNFVEVVIAPSFTKEARGIFSKKKNLRLIQLPINSEKYP
YFNIKRVRGGILLQDADTIEEDRSNWNVVTEAKPDEETFKALEFAWKVVKHVKSNAIVFC
KENETLGIGAGQMSRVDSVKIAVMKANKDLNGSVLASDAFFPFRDSIDEAAKIGVKAVIQ
PGGSIRDKEVIEAANEHGIAMVFTGIRHFRH
NT seq 1536 nt   +upstreamnt  +downstreamnt
atgaaaagatacgctttaatttctgttagtgataaaaacggtattgttgattttgcaaaa
aagcttgaaaatttaggctttgaaatagtttcaagtgggggaacttttaaagtgttgaaa
gatgcagggttgaatcccgttaaggtttctgatattacaggtttccctgaaatacttgac
ggcagggttaaaacccttcacccaaaaattcacggtggaatacttgtagatatgagaaaa
gaaagccatagagaagagttgaaaaaacacggcattaataactttgagatagtctgcgtt
aacctttacccatttaaagaaacagttaaaaaaacagatgatgttgacgagattattgaa
aacattgacattggcgggccaacccttttaagggcttctgcaaagaatttttactctgtt
gcagttgtagttgaccctgatgattactcaaaggttgttgaggaaattgagaaaaacggt
gaagtgtcccttgatacaagaaagaaacttgcattaaaggctttgtcccatacagcatct
tacgatattgcaatatcctctttctttaatagaatgcttgaaaataaatttcctgagagg
ttgtttcttgaatacaaccttgagaacacattgaggtacggggagaacccccatcagcaa
gctgctttttacagcgagcctgattttaggaatgatgaattgcctgctttgaaaaaattg
cagggtaaggagttatcatacaacaacttaatggattctgatgctgcaattgaaatggta
agggagtttgatgagcctgcgtgcgtaatcgtaaaacatgctaacccctgcgggatagga
agggataatgaatctttaaaaattgcttttgaaagggcacactccactgacccgatgtct
gcctttgggggcattattgctttaaacagagaggttgacggtgagcttgcctctctgatt
actaaaaattttgttgaggttgtaattgccccttcctttacaaaggaagcaagggggatt
ttttcaaaaaagaagaatttaaggctaatccaattgcccattaactctgaaaaataccct
tacttcaacataaagagagtaaggggtggaatacttttgcaggatgctgacactattgaa
gaggacagaagcaattggaatgttgtaacagaggcaaagcctgatgaggagacatttaag
gctttggagtttgcatggaaggttgtaaagcatgtaaaatcaaatgcaattgttttctgc
aaggaaaatgaaactcttggtattggggcaggccagatgagcagggttgattcagttaaa
attgccgtgatgaaggcaaataaggatttaaacggaagtgtgcttgcatctgacgccttc
tttccttttagagatagcatagacgaagctgcaaaaataggggtaaaggctgttattcag
ccaggcggttcaattagggataaagaggtaattgaggctgcaaatgagcatggaattgct
atggtgtttaccggcatcaggcacttcaggcattaa

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