Thermotoga sp. Cell2: CELL2_02000
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Entry
CELL2_02000 CDS
T03495
Name
(GenBank) putative alpha-isopropylmalate/homocitrate synthase family transferase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
thz
Thermotoga sp. Cell2
Pathway
thz00290
Valine, leucine and isoleucine biosynthesis
thz00620
Pyruvate metabolism
thz01100
Metabolic pathways
thz01110
Biosynthesis of secondary metabolites
thz01210
2-Oxocarboxylic acid metabolism
thz01230
Biosynthesis of amino acids
Module
thz_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
thz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
CELL2_02000
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CELL2_02000
Enzymes [BR:
thz01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
CELL2_02000
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
SpoIISA_toxin
Motif
Other DBs
NCBI-ProteinID:
AIY87740
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Position
complement(363724..365340)
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AA seq
538 aa
AA seq
DB search
MSIKVYDTTLRDGAQAFGVSFSLEDKIRIAEALDDLGVHYLEGGWPGSNPKDIAFFEAVK
GMNFKNLKVAAFSSTRRPDVKIEEDANIQTLIKAETPVYTIFGKSWDLHVEKALRTTLEE
NLKMIYDTVSYLKRFADEVIYDAEHFFDGYKANREYALKTLKVAEEAGADCLVLADTNGG
TLPHEIEEIIEDVKKHVKAPLGIHAHNDSDVAVANTLAAVRKGAVHVQGTINGLGERCGN
ANLCSVIPNLVLKMGLEVIPKENLKKLFDVAHLVAELSGRPHIENMPYVGDYAFAHKGGV
HVSAIKRDPRTYEHIDPELVGNRRIISISELSGKSNVLEKIKEMGFEIDESSPKVREILK
KIKELEAQGYHFEGAEASFELLVRDMLGKRKKYFEFLGFTVMTIKNRDEESFSEATVKVR
VPDEVAKRLGHDEPFEHTAAEGEGPVEALDRAVRKALEKFYPSLKDTKLTDYKVRILNEQ
AGTKATTRVLIESSDGKRRWGTVGVSPNIIEASWTALLESLEYKLHKDEEEMRNDEEN
NT seq
1617 nt
NT seq
+upstream
nt +downstream
nt
ttgagtataaaggtctacgatacaacgctcagggacggtgcgcaggcctttggagtttct
ttctcactcgaagataagatcagaattgccgaggcactcgatgacctcggtgttcactat
cttgaagggggttggcctggctccaacccgaaggatatagcgttttttgaagctgtaaaa
ggtatgaacttcaagaatctgaaagtggcggccttcagttccacaagaaggcccgatgtg
aaaatagaagaagacgcgaacattcaaaccctcataaaagcggaaacacctgtttacacg
atctttggaaagagctgggatcttcacgtggaaaaagccttgcgaacgacactcgaagag
aatctgaagatgatatacgacacagtttcatatctcaaaagattcgccgatgaggtgata
tacgacgcggaacacttcttcgatgggtacaaggcgaacagagagtacgccctcaaaact
ctgaaggtggctgaagaagcgggggctgattgtctcgttctcgctgacacgaacggtgga
acgcttccacacgagatcgaggagatcatcgaggatgtgaaaaagcacgtgaaagctccg
ctcggaatacacgctcacaacgattcggatgtggcggtggcgaatacactcgcggctgtg
agaaagggagccgtgcacgtccaggggaccataaacggccttggagagagatgtggaaac
gcgaatctctgttcggtgattccgaatctcgttctcaagatgggacttgaggttatacca
aaggaaaacttgaagaagctcttcgatgtggcacacctcgtggcagaactctccggaagg
ccccacatcgagaacatgccctatgtgggtgattacgccttcgctcacaagggaggagtc
catgtttctgccataaaacgcgatccaaggacttacgaacacatcgacccggaactcgtg
gggaacagaaggatcatatccatctcggaactttccggtaagagcaacgtgctggagaag
ataaaggaaatgggattcgaaatagatgagtcatcgcccaaggtcagggagatcctcaaa
aagatcaaggaattggaagcgcaggggtaccacttcgagggtgcggaggcatctttcgag
cttctcgtcagggatatgctcgggaaaagaaagaagtactttgagtttctcggtttcacc
gtgatgaccataaagaacagggatgaggagagtttctccgaagcaaccgtgaaagtcaga
gtcccggacgaagttgcgaagagactgggacacgacgaaccctttgaacacacagcagcg
gaaggagaaggaccggtagaagcgctcgacagagcggtgagaaaagccctcgagaaattc
tatccatctttgaaagacacgaaactcacggactacaaggtgagaatcctgaacgagcag
gcgggcaccaaagcgacaacacgggttctcatagagtccagcgatggaaagagaaggtgg
ggaactgtgggcgtctcaccgaacatcatagaggcttcctggaccgctcttctcgaatcc
ttagagtacaagcttcacaaggatgaagaggagatgagaaacgatgaggagaattaa
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