Thiomicrolovo immobilis: WCX72_04180
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Entry
WCX72_04180 CDS
T11235
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
timm Thiomicrolovo immobilis
Pathway
timm00300
Lysine biosynthesis
timm00550
Peptidoglycan biosynthesis
timm01100
Metabolic pathways
timm01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
timm00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
WCX72_04180 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
WCX72_04180 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
WCX72_04180 (murF)
Enzymes [BR:
timm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
WCX72_04180 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
XAU06194
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Position
810200..811642
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AA seq
480 aa
AA seq
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MNPALAQTVAFATNVALVLTLGWYLILNLQWYSYKLERVVLNHHKRSWHLLYFVVPFLAY
FILGEFFPLFFLLYFGAFVWWYVRLDKKLVLTWRVKRFLILLSALALFGDFLCLIKSCGT
LPLFLPLLLAWLLSTGIEKFLFLAYKKEAKRKLARLEGLTVVAVTGSYGKTSMKNFIAQL
LGTQFEVYMTPRSVNTLGGIIKDINEALPETARVYVCEAGARRPGDILEIAQLVAPHYAV
VGKVGPQHLEYFGDLETIVRTKLELIQSPRLKQAFVHFEATDEPHEKVRFFGREIENIAA
DLDGTSFDLALDEAPLQLHAPVLGGFNAVNIEAAVLIARAMGMTDDAIMKGVDALQPVEH
RLQRIDAGGKVILDDGYNGNIDGMKEGIRLCSMHPGRKVIVTPGLVESTEALNRELIEAI
NGVFDLVIVTGKLNAAQFKAQLNVSDVLYLEEKSTLTSVLAEKTRPGDIIYFANDAPNFI
NT seq
1443 nt
NT seq
+upstream
nt +downstream
nt
gtgaacccggcgctcgcgcagaccgtggcgttcgcgaccaacgttgcgctggtcctgacg
ctcgggtggtatctcatccttaacctgcagtggtacagctacaagctcgagcgcgtcgtg
ctcaaccaccacaaacgcagctggcaccttctctacttcgtcgtgccgttcctagcctat
ttcatcctcggcgaatttttcccgctctttttcctgctctatttcggcgcgttcgtctgg
tggtacgtgcgcctggacaagaaactggtgctgacctggcgggtcaagcgtttcctcatc
ctgctcagtgcgctggcgctgttcggcgatttcctctgtcttatcaagagctgcggcacc
ctgccgcttttcctcccgctgctgctggcgtggctgctctccacgggcatcgagaaattc
ctcttcctcgcctacaaaaaagaggcgaagcgcaaactggcccgcctggaggggctgacc
gtcgttgccgtgacggggagctacggcaaaacgagcatgaagaacttcatcgcccagctg
ctcggaacgcagttcgaggtctacatgacgccgcgcagtgtcaataccctgggcggcatc
atcaaagatatcaacgaagcgcttcccgaaacggcccgggtttacgtctgtgaggcgggg
gcgcgccgtcccggcgacattctggagatcgcccagctcgtggcgccgcactacgccgtc
gtcggcaaggtcgggccgcagcacctggagtatttcggcgatctggagacgatcgtgcgc
accaagctggagctgatccagtcaccccgcctgaaacaggccttcgtacactttgaagcg
acggatgagccccatgaaaaggtgcgcttcttcggcagggagatcgaaaatatcgccgcc
gatctcgacgggacgtcgttcgacctcgcccttgatgaggcacccctgcagctgcatgct
ccggtcctcggcggcttcaacgccgtgaacatcgaggcggccgtgttgatcgcgcgggcg
atggggatgacagacgacgccatcatgaaaggggtcgatgccctccagcccgtcgaacac
cgtctgcaacgcatcgacgccggcggcaaggtcattctcgatgacggctataacggcaat
atcgacgggatgaaggaggggatccgcctctgttccatgcacccgggacgcaaagtgatt
gtcaccccggggctggtggagagcacggaagccctcaaccgcgaactgattgaggcgatc
aacggggtgttcgaccttgtcatcgtcaccggaaaactcaatgccgcgcagttcaaagca
cagctgaacgtttcggacgtcctctacctcgaagagaagagcaccctgacctccgtgctg
gccgagaagacgcgcccaggcgacatcatctatttcgccaacgacgccccgaactttatc
tag
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