Thermophilibacter immobilis: INP52_01585
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Entry
INP52_01585 CDS
T07753
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
tio
Thermophilibacter immobilis
Pathway
tio00230
Purine metabolism
tio01100
Metabolic pathways
tio01110
Biosynthesis of secondary metabolites
Module
tio_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
tio00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
INP52_01585
Enzymes [BR:
tio01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
INP52_01585
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
QOY60930
UniProt:
A0A7S7RUT1
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Position
complement(353019..356750)
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AA seq
1243 aa
AA seq
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MVSRIYVEKKPGFDGEARTLERELTGLLGISALTNVRIINRYDVEGISSELFETCVPTVF
SEPQTDDVSPQIPEVVGATVFAVEFLPGQFDQRADSASECIQLISQGERPLVRSARVYVL
EGPLSEADVASVKRYVINPVEAREASLEPRATLSARHLEPEPVETLDAFSALDAAALAAF
IERRGLAMDLADLQFCQTYFAGEHRDPTITEIKMIDTYWSDHCRHTTFGTALEHVQFDDQ
VVAAAFDRYLQMRHELGRDHKPVCLMDMGTIGAKWLAHTGQLTGLDESEEINACTVKVTV
DVDGRDEDWLFLFKNETHNHPTEIEPFGGAATCIGGAIRDPLSGRSYVYQAMRVTGAADP
TLPVSQTLPGKLPQRKLVTTAATGYSSYGNQIGLATGQVAELYHPGYVAKRMEIGAVVAA
TPASHVRRERPAPGDVIVLLGGRTGRDGIGGATGSSKAHKVESLEKDGAEVQKGNAPVER
KLQRLFRREDACRLIKRCNDFGAGGVSVAIGELADGLDIDLDLVPKKYEDLDGTELAISE
SQERMAVALAPADVDEFLGYAREENLEATAVATVTAAPRLRMSWNGATIVDVSREFLASN
GAPKSTSVHVSAPREFSRTWVGDTVAQKMRSLVCDLNVASHKGLSERFDSTIGAATVLMP
FGGRTQLTPTMAMVAKLPVDGETTTCSGMAWGFNPYLMSANPYTGAYLSVVESVCRMVAT
GFAHEDLYLTFQEYFEKLRDDPYRWGKPTAALLGALMAQVDLGIGAIGGKDSMSGSFEDL
DVPPTLVSFATGLARVDRMVSPEFKGTGHRVLVVVPDYAADGLTPDSDALLATFSLVEDM
IARGDALSVSTVGYGGAAEAVFKMCVGNLLGLEVAPAFGAQALFCPSYGSFLVELSDDAA
LPEVARNVALSQFGTTTQAYELVVDEERIDLCKLQEAWEGALEPVFPYRAPGEKVERVSF
DLTAQGATRPTPVLHVAHPRVVIPVFPGTNCEYDTARAFERVGAEPHVLVINNLTPTSVA
ESTHELARLIGQSQIVMLPGGFSGGDEPDGSAKFITAFFRAPEITEAVRDLLQSRDGLML
GICNGFQALVKLGLVPSGDIRPMDETCPTLTFNTIGRHQSRLVRTRVASNLSPWLSRCEV
GDVHNVAISHGEGRFVASPELVARLAARGQIATQYVDENGQPGMALDVNPNGSVLAIEAV
TSPDGRVLGKMGHSERSGRGLYQNVPGNSYQPLIEGGVDYFTA
NT seq
3732 nt
NT seq
+upstream
nt +downstream
nt
atggtctctcgcatctacgtggagaagaagcccggattcgatggagaggccaggacgctc
gagcgcgagctcacggggctccttggcatcagcgccctcaccaacgtgcgcatcatcaat
cgctatgacgttgagggcatctcttccgagctcttcgagacctgcgtgcccacggtcttc
tcagagccgcagaccgacgacgtcagcccccagattcccgaggtcgtaggcgccacggtc
tttgccgtggagtttctccccggccagttcgaccagcgcgccgactccgcgagcgagtgc
atccagctcataagccagggagagcggcccctcgtacgctccgccagggtctacgtgctc
gagggccccctgagcgaggccgacgtcgcgtccgtcaagcgctacgtgatcaaccccgtc
gaggcccgcgaagcctcgctcgagccgcgcgccaccctgtccgcgcgccatcttgagccc
gagccggtggagaccctcgacgccttctccgcgctcgatgcggccgccctggccgccttc
atcgagaggcgcgggctggccatggacctcgccgacctccagttctgccagacgtacttt
gccggcgagcaccgcgaccccacgatcaccgagatcaagatgatcgacacctactggtcc
gaccactgccgccacaccacctttggcacggcgctcgagcacgtccagttcgacgaccag
gtcgtggctgccgcgttcgaccgctacctgcagatgcgccacgagctcggccgcgaccac
aagcccgtctgcctcatggacatgggcacgatcggcgccaagtggctcgcccacaccggg
cagctcaccggcctcgacgagtccgaggagataaacgcctgcaccgtcaaggtcacggtg
gacgtagatggacgcgacgaggactggctcttcctcttcaagaacgagacccacaaccac
ccgacggagatcgagcccttcggcggcgcggcaacctgcatcggcggggccatccgcgac
ccgctctcggggcgctcctacgtctaccaggccatgcgcgtgaccggcgcggccgacccc
acgctccccgtgtctcagacgctcccaggcaagctcccgcagcgcaagctcgtgaccacc
gccgcaaccggctactcaagctacggcaaccagatcggcctggcaaccgggcaggtcgcg
gagctctaccaccccggctacgtggctaagcgcatggagatcggcgccgtcgtagccgcc
acgccggcctcgcacgtgcgccgcgagcgccccgcccccggcgacgtgatcgtgcttctc
ggcgggcgcaccggccgcgacggcatcggcggcgccacgggctcatccaaggcccacaag
gtcgagtccctcgagaaggacggcgccgaggtccagaagggcaacgcccccgtcgagcgc
aagctccagcgcctctttcgccgcgaggatgcctgccgcctcatcaagcgctgcaacgac
ttcggcgcgggcggcgtaagcgtggccatcggcgagctggccgacggcctggacatcgac
ctcgacctcgtccccaagaagtacgaggacctggacggcaccgagctcgccatctccgag
agccaggagcgcatggccgtggccctggcccccgcagacgtcgacgagtttctgggctac
gcccgcgaggagaacctcgaggccaccgcggtggccaccgtcacggccgcgccgcgcctg
cgcatgagctggaacggcgccacgatcgtggacgtgagccgggagttcctggcctccaat
ggggcccccaagtccacctccgtgcacgtgagcgcaccccgggagttctcgcgcacctgg
gtgggcgacacggtcgcacagaagatgcgctccttggtctgcgacctcaacgtggcctcc
cacaagggactctccgagcgcttcgactccaccatcggcgctgccacggtcctcatgccc
ttcggcgggcgcacgcagctcacgcctaccatggccatggtcgccaagctccccgtggac
ggcgagaccaccacctgctccggcatggcctggggcttcaacccctacctcatgagcgcc
aacccgtacacgggcgcctacctgagcgtcgtcgaatccgtctgccgcatggtggcaacc
ggctttgctcacgaggacctctacctcacgttccaggagtacttcgagaagcttcgcgac
gacccctatcgctggggtaagcccaccgcagcccttctcggcgccctcatggcccaggtc
gacctgggcatcggcgccatcggcggcaaggactccatgtccggcagcttcgaggacctc
gacgtgcctcccaccctcgtctcgtttgccacggggctcgcgcgcgtggaccgcatggtc
tcccccgagttcaagggcacgggccatcgcgtgctggtcgtggtgcccgactacgccgca
gacggcctcacgcccgactccgatgcgcttctggccacgttctcgctggtcgaggacatg
atcgcgcgcggcgatgcgctgagcgtctccacggtcggctacggcggggccgccgaggcc
gtgttcaagatgtgtgtgggcaacctcctgggcctggaggtggctcctgcctttggcgcg
caggccctcttctgtccctcctacggcagctttctcgtggagctctccgacgacgccgcg
ctgcccgaggtcgcccgcaacgtcgcgctctcccaatttggcaccacgacccaggcctac
gagctcgtggtcgacgaggagcgcatcgacctttgtaagctgcaggaggcctgggagggc
gccctggagccggtcttcccgtaccgagcgcctggcgagaaggtcgagcgcgtctcgttt
gacctcacggcgcagggggccacgcgtcccacgcccgtccttcacgtggcgcatccgcgc
gtggtgatcccggtcttccccggcaccaactgtgaatacgacaccgcccgagccttcgag
cgcgtcggtgccgagccccacgtgctcgtgatcaacaacctcacgcccacgagcgtcgcc
gagagcacccatgagctcgcgcgcctgatcggccagagccagatcgtcatgctccccggg
ggcttctccggcggagacgagcccgacggctccgccaagttcatcaccgcgttcttccgc
gcccccgagatcaccgaggccgtgcgcgacctcctgcagagccgcgacggcctcatgctg
ggcatctgcaacggcttccaggcgctcgtcaagctcggcctggtcccctctggcgacatc
cgcccgatggacgagacctgccccacgctgacgtttaacaccatcggccgccaccagagc
cgtctggtgcgcacccgcgtggcctcgaacctctcgccctggctctctcgctgcgaggtc
ggtgacgtccacaacgtggcgatatcccacggcgagggtcgcttcgtggcatctcctgag
ctcgtggcaaggctcgccgccagggggcagatcgccacgcagtacgtggacgaaaacggc
cagcccggcatggcgctcgacgtcaaccccaatggctcggtcctggccatcgaggccgtc
acgagccccgacgggcgcgtgctcggcaagatgggccacagcgagcgcagcggacgcggg
ctctaccagaacgtgcccggcaactcctaccagcccctcatcgagggcggcgtggactac
ttcacggcgtag
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