Thermoanaerobacter italicus: Thit_1486
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Entry
Thit_1486 CDS
T01178
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tit
Thermoanaerobacter italicus
Pathway
tit00300
Lysine biosynthesis
tit00550
Peptidoglycan biosynthesis
tit01100
Metabolic pathways
tit01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tit00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Thit_1486
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Thit_1486
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Thit_1486
Enzymes [BR:
tit01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Thit_1486
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Chordopox_G2
Motif
Other DBs
NCBI-ProteinID:
ADD02742
UniProt:
D3T3E0
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All DBs
Position
complement(1499268..1500653)
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AA seq
461 aa
AA seq
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MMELLIAEIVRATQGKLIKGSLKDKIIGISTDSRKVKKDELFIPLKGEKYDGEDFVKDAM
TKGAKAVLTARLDNIEYLKDFPFNIIYVNDTLEALHKIAYYYRKKFNIPFVAVTGSTGKT
TTKDMIAQILSKKYKVLKTEGNFNNEIGLPLTIFNLENTHQIAVVEMGMSGFGEIRRLKN
IVKPQVAVFTNIGVAHIEKLGSRENILKAKTELIEDFKEENVIVLNADDDMLLKILQQYS
SKYYRYGIKSGEIKACDIEKGEKGIEYTLKYKNLEKEIKLSIPGIHNVYNSLAAICVGLE
FGVDVDDMAEALKDFQPGKMRLNIIEKGDIKIIDDAYNANPDSMKAALNVLRDFPGKRKI
AVLGDMLELGEYAVEAHKEIGKLVADSHIDILITSGNTSKYIAEESKVCGMKENNIFVCN
TNEEVKEILKDIIKEGDLILVKGSRGMKMEQIVQFLQERVN
NT seq
1386 nt
NT seq
+upstream
nt +downstream
nt
atgatggaacttttaatagctgaaattgtaagggccacacagggaaaattgataaaagga
agtttaaaggataaaataataggaatttcgactgattcaagaaaagtcaaaaaagatgaa
ttatttattcctttgaaaggagaaaaatacgatggagaagattttgtaaaagatgcgatg
acaaaaggtgctaaagcagtcctcactgccaggttagataatatagagtatttaaaagat
tttccatttaacattatttacgtaaatgatactttagaggctttgcataagatagcttat
tactatagaaaaaaattcaatatcccatttgttgctgtgacaggtagcactgggaaaact
actacaaaagatatgattgcgcaaatattgtctaaaaagtataaagtgttgaaaacagaa
ggtaattttaataatgaaataggtttgccattgacaatttttaatttggagaatactcat
caaattgcggtagtggaaatgggaatgagtggttttggagaaattaggaggttaaagaat
attgtaaagccgcaagtggcagtttttacaaatataggagttgctcatattgaaaaatta
ggttcaagggaaaatatattaaaagcaaaaacggagttgattgaagattttaaagaggaa
aatgtgattgtattaaatgcagatgatgatatgctattaaaaattcttcagcagtattca
agtaagtattacagatatggtataaaaagtggagaaattaaagcttgcgatatagaaaaa
ggagaaaaaggtatagaatatactttaaaatataaaaatttagagaaagaaataaagctt
tcaatacctggtattcataatgtgtacaattctcttgctgctatttgtgttggattagag
tttggggttgatgtagatgacatggcggaggctttaaaagattttcaaccaggtaaaatg
agactcaatataatagaaaaaggtgacataaaaattattgatgacgcatataatgccaat
ccagattctatgaaagcagctttaaatgtcttgagggattttcctggcaaaagaaaaata
gcagttttaggagatatgctggaattaggtgagtatgcagtagaagcccacaaagaaata
ggaaaattggtggcagatagccatatagatattttgataacttctggtaatacgtcgaaa
tatattgcagaagaatccaaggtttgtggaatgaaagagaataatatttttgtttgtaat
actaacgaagaagttaaggaaatattgaaagatattatcaaagaaggagatttaatttta
gtgaaaggttcaagaggtatgaaaatggagcaaatagtacaatttttgcaggagagggta
aactaa
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