Thermoanaerobacter italicus: Thit_1620
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Entry
Thit_1620 CDS
T01178
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
tit
Thermoanaerobacter italicus
Pathway
tit00290
Valine, leucine and isoleucine biosynthesis
tit00620
Pyruvate metabolism
tit01100
Metabolic pathways
tit01110
Biosynthesis of secondary metabolites
tit01210
2-Oxocarboxylic acid metabolism
tit01230
Biosynthesis of amino acids
Module
tit_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
tit00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Thit_1620
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Thit_1620
Enzymes [BR:
tit01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Thit_1620
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
ComA
Motif
Other DBs
NCBI-ProteinID:
ADD02871
UniProt:
D3T3R9
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All DBs
Position
complement(1631536..1633098)
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AA seq
520 aa
AA seq
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MKNLRIYDTTLRDGVQGQGISFTVEDKLKIVKALDEFGVAYIEAGNPGSNPKDIEFFERV
KNIKLKNAKLIAFGSTRRANTTTEEDANVISLLNADTEVVTIFGKSWDFQVIEILKTTLE
ENLKMIYDTIKFFKDKGKSVIFDAEHFFDGYKQNPEYALKTLEVALEAGADSVCLCDTKG
GAFPMEVYEITKTVVDKFNTEVGIHCHNDNGMAVADSIMAVHAGAIQVQGTINGYGERCG
NANLCTLIPNLQLLMGYKCVPDENLKQLTHLARFVSEIANVTHDERAPFVGKNAFAHKAG
MHADAVNKNTYSYELIDPSLVGNSRTFLISEVAGRGAVLNAINEIDPTIKKNSPETKLIL
DRLKEMEYLGYQYENAGGSLELLIRKVLGRYKPAFNLKEFKVIVNEPSVNSVNSFAIIKV
EVDGVEEIAAADGDGPVHALDNAVRRVLERFYPQIKEMRLTDYKVRVLDSNSATAAKVRV
IIESTDGKDSWSTIGVSTDIIEASWRALVDSIEYKLNKEN
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
gtgaagaacctacgtatatacgatacaacattaagagacggagttcaaggacaaggtata
tcttttactgtggaagataaattaaaaatagttaaagcgcttgatgagtttggggtagcc
tatattgaggcaggtaatcctgggtctaatcctaaggatattgagttttttgaaagagtt
aaaaatattaaattaaaaaatgctaaattaatcgcttttggtagcacaagaagagcaaat
acaactaccgaagaggatgctaatgtgatttcacttttaaatgctgacacagaggtagta
actatctttggcaagtcatgggattttcaagttatagaaattttgaaaaccactttagaa
gaaaacttaaaaatgatttatgatacaataaagttttttaaagacaaaggtaagtcagtt
atatttgatgcagagcatttttttgatggttacaaacaaaatccagagtatgctttaaag
acattagaagtagcattagaggcgggcgcagacagtgtatgcttgtgcgatacaaaaggc
ggagcttttcctatggaggtttatgaaataacaaaaactgttgtggataaatttaataca
gaagtagggatacactgtcataatgataacggaatggctgttgcagattccataatggca
gtacatgcaggtgcaatacaagtacaaggtacaataaacggttatggtgaaagatgtggt
aatgcgaatttatgtaccttgataccgaatttgcaattacttatgggatataaatgtgtg
cctgatgaaaatctaaaacaattgactcatttagcaaggtttgtaagtgaaattgcaaat
gtcactcacgatgaaagagcaccttttgtgggaaaaaacgcatttgcccataaagctgga
atgcatgctgatgctgtaaataaaaatacttactcttatgaactgattgacccgtcttta
gtgggaaatagcagaacctttttaatttctgaagttgctggaagaggagcagttttaaat
gctataaacgagatagacccaaccatcaaaaaaaattcacctgagacaaaattaattctt
gataggctaaaagaaatggagtatttggggtatcaatatgaaaatgcaggaggctcatta
gaacttttgataagaaaagtccttggaagatacaagccagcctttaatttaaaagaattt
aaagttattgtaaatgaaccttctgtcaatagtgttaattcttttgcaattataaaggtg
gaagtagatggagtggaagaaatagccgctgcggatggagacggaccagtgcatgccctt
gataatgctgtaagaagggttttggagagattttatccacagataaaagagatgaggttg
acagactataaagtgagggttttggattctaattctgcaactgctgctaaagtgagggtt
ataattgagtctacagacggaaaagattcttggagcacgattggggtttctacagatatt
attgaagctagttggagggcacttgttgattcaatagaatataaactaaataaggagaat
tga
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