Thermincola potens: TherJR_2164
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Entry
TherJR_2164 CDS
T01226
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tjr
Thermincola potens
Pathway
tjr00300
Lysine biosynthesis
tjr00550
Peptidoglycan biosynthesis
tjr01100
Metabolic pathways
tjr01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tjr00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
TherJR_2164
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TherJR_2164
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TherJR_2164
Enzymes [BR:
tjr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
TherJR_2164
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ADG83009
UniProt:
D5X9A5
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All DBs
Position
complement(2236598..2237974)
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AA seq
458 aa
AA seq
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MYKMTLGEIAGAIKARMVKGNVDRVYTQVCTDSRQIVPGSLFVALKGERFDAHDFVEQAL
QLGAHGVIVSRMQHDLPDGDILLVDDTLTALQQLARYNRKKFSGPVVAVTGSNGKTTTKD
MISALLETKYLVLKTLGNFNNEIGLPLTLLGLDESHGAVVVEMGMRGLGEIDFLARIACP
TAGVITNIGETHLERLGTVENIARAKTELLPHIPVGGYAVLNGDDPWQRKYAHLTRAKVI
FYGMDHSNHVYADNIKCNMGAGASFTVIRDKIAKVFHLPVPGRHNIYNALAAITVGLQEG
LSWEMCMEGLQNVVLSGMRLQIIDCNGLKIINDTYNANPASSKAAVRILAEMPCAGKKVA
VLGDMYELGQRTVQGHREVGETVQNLKIDILVTVGELALHIAEAAKAAGMDRKNIYVSRN
NNEALEILNNILKAGDLVLVKGSRGMKMEKIVEGITCA
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
atgtataaaatgacactcggagaaattgccggcgctatcaaggcacgcatggtaaaagga
aatgtggaccgcgtttatacgcaggtttgtaccgattcgcggcagatagttccgggcagc
ctttttgtggcattaaaaggggagcgttttgatgcccatgattttgtagagcaggctttg
cagcttggggcgcatggggtaattgtgagccggatgcagcatgaccttcccgacggtgat
atccttttggtcgatgatactctgacagctttgcaacaacttgcccggtataacagaaag
aagttctccgggccggttgtggccgtaacaggcagcaacggtaaaacgaccaccaaggat
atgatttctgctttgttggagacaaaatacctggttctgaaaacattgggtaattttaac
aacgaaattgggcttcccctgacccttttgggtttggacgagtctcatggcgccgtagtt
gtggaaatgggcatgcgtgggctcggggaaatagatttcctggcccggattgcctgtcct
accgccggagtaataacaaatatcggcgaaacccacctggagcgattgggtacagtggaa
aatattgcccgggcgaaaactgagctgctgccgcatattcctgtcggcgggtatgcagtt
ttgaacggtgacgacccctggcagcgaaagtatgcgcacctgacgagggcaaaagtaata
ttctatggtatggatcattccaatcacgtctatgccgacaacataaaatgtaacatgggc
gccggtgcgagtttcaccgtaatacgcgacaaaattgcaaaggttttccacctgccggta
cctggcaggcacaacatatataatgccctggcggccattaccgtcggtctgcaggaaggg
ctttcgtgggaaatgtgcatggaaggtttgcagaatgttgtgcttagcggtatgaggctg
cagattattgactgcaatggcttgaaaataatcaatgatacatataatgccaatcctgca
tcaagtaaagctgctgtccgcatacttgccgagatgccctgtgcagggaaaaaagttgcc
gttttaggggatatgtatgaattgggacaacggacagtacagggacaccgcgaagtagga
gaaactgtgcaaaatttaaaaattgatatcctggtaactgttggggaattagcactgcac
attgcagaagcggctaaagcggcgggtatggataggaaaaatatttatgtgagtagaaat
aacaatgaggcattggagattcttaataatatattgaaagccggcgacctggtattggta
aaaggttcgcggggaatgaaaatggaaaaaattgtggaaggaattacctgtgcctaa
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