Thioalkalivibrio sp. K90mix: TK90_2205
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Entry
TK90_2205 CDS
T01174
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tkm
Thioalkalivibrio sp. K90mix
Pathway
tkm00300
Lysine biosynthesis
tkm00550
Peptidoglycan biosynthesis
tkm01100
Metabolic pathways
tkm01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tkm00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
TK90_2205
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TK90_2205
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TK90_2205
Enzymes [BR:
tkm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
TK90_2205
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Lipase_GDSL_2
Motif
Other DBs
NCBI-ProteinID:
ADC72695
UniProt:
D3SD96
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Position
complement(2322111..2323484)
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AA seq
457 aa
AA seq
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MIRMTGQELADAVRGRLENGDGERVFEGVFTDTRQPLEGGLFVALRGPRFDAHEHVAADL
PAAVLLVERVLDVPHPQVVVADTGEALGRLAQHWRRRSRARVIALTGSNGKTTTKEMLRC
ILEGVGSVHATQGNLNNEIGVPLTLLAMPEDTDYAVIEMGANHAGEIGRMARWTEPMVAM
ITNAGRAHLEGFGSLEGVAHAKAEIFSGLPSQGGTAVINLDDPFADYWLSLNEHHHCQRF
SLEGGGEIEGVWQAPDRLRLTILGAGRDLRLASPGRHVAANAIAAAAAANAVGVAIDAIA
NGLAGWTPVQGRLQELWHVSGARLWDDTYNANPDSLRAGLEVLAAMPGRRILVLGAMGEL
GAETPVLHRETGALARAMGVDYCLALGEAARDSAEAFGEGGEWFADHDALRTRLEALLED
ETTVLIKGSRSQHMERIIEGLETAPSARGAANAVRAD
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
atgatccggatgaccggacaggaactggcggacgccgtgcgcggccgtctggaaaacggc
gacggcgagcgggtcttcgagggggtgttcaccgacacccggcaaccgctcgaaggaggg
ctgttcgtggcgctgcgcggcccgcgctttgatgcccacgagcatgtcgccgccgacctg
ccggccgctgtgctactggtggagcgcgtgctggatgtcccgcacccgcaggtggtcgtg
gccgataccggcgaggccctgggccggctggcccagcactggcgccgccgcagccgggcg
cgggtgatcgcgctgaccggctccaacggcaagaccaccaccaaagagatgctgcgctgc
atcctcgagggcgtgggctcggtgcatgccacccagggcaacctgaataacgagatcggc
gtgccgctgacgctgctggccatgcccgaggacaccgattacgcggtgatcgagatgggc
gccaaccatgccggcgagatcgggcgcatggcgcgctggaccgaaccgatggtcgccatg
atcaccaacgccgggcgggcccatctggagggctttggcagccttgagggggtggcccac
gcgaaggccgaaatcttctcggggctgccgtcccagggcggtacggcggtgatcaatctg
gacgacccgttcgccgactattggctgtcgctgaacgagcaccaccactgccagcgcttt
tccctggagggcggtggcgagatcgagggtgtgtggcaggcccccgaccgcctgcgtctg
acgatcctgggcgccggccgtgacctgcgtctggccagcccggggcgccatgtcgctgcc
aatgcgatcgccgcggccgccgcggcgaatgcggtgggtgtggcgatcgacgcgatcgcc
aacggtctggcgggctggacgccggtgcaggggcgtttgcaggagctctggcatgtcagc
ggtgcccgcctctgggacgacacctacaacgccaaccccgactcgctgcgcgcggggctc
gaggtgctggccgcgatgcccggccggcgcatcctcgtgctgggtgcgatgggggaactg
ggcgccgagaccccggtgctgcaccgtgagaccggggcgctggcccgcgcgatgggtgtg
gactactgcctggccctgggcgaggccgcgcgcgacagcgccgaggcgtttggcgagggc
ggcgagtggtttgccgaccatgacgccctgcggacgcgcctggaagcactgctggaggac
gagaccacggtcctgatcaagggctcgcgcagccagcacatggagcgaatcatcgaaggg
ctggagacggccccgtcggcgcggggggctgcgaatgctgtacgcgctgactga
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