KEGG   Thermococcus kodakarensis: TK1736
Entry
TK1736            CDS       T00226                                 
Name
(GenBank) ribonucleoside-diphosphate reductase
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
tko  Thermococcus kodakarensis
Pathway
tko00230  Purine metabolism
tko00240  Pyrimidine metabolism
tko01100  Metabolic pathways
tko01232  Nucleotide metabolism
Brite
KEGG Orthology (KO) [BR:tko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    TK1736
   00240 Pyrimidine metabolism
    TK1736
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:tko03400]
    TK1736
Enzymes [BR:tko01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     TK1736
DNA repair and recombination proteins [BR:tko03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    TK1736
SSDB
Motif
Pfam: Ribonuc_red_lgC Endonuc_subdom Intein_splicing Stirrup LAGLIDADG_3 ATP-cone Ribonuc_red_lgN Hom_end LAGLIDADG_WhiA PT-HINT
Other DBs
NCBI-ProteinID: BAD85925
UniProt: Q5JJ43
LinkDB
Position
1530735..1535975
AA seq 1746 aa
MPVEKVMKRDGRIVPFDKERIRWAIQRAMLEVGVRDEKLLNRVVRRVVRRVNELYDGQIP
NIENIQDIVELELMRAGLFDVAKAYILYRKKKAEIREEKKKILNKDKLDEIDKRFSLNAL
RVLASRYLIKNEKGEIIESPRELFERVAILAVIPDILYDERVFDKNGGHEQDVSAIERYR
ENLDEYDGKFSIGRFRLNKWHFERLLNLYRELAEKGQMKLPIDEVLKMLENGAFDNYEDE
IEEYFRLMTGQYFMPNTPALINSGRPLGMLSACFVVPIEDDMESIMKAAHDVAMIQKAGG
GCIDGNAKIIFENDGEEHIMTMAEMYERYKDLGEFYDPEYNRWGINVEEVPVYVKSFDPS
TKEITKGKVKVIWKYELGEDVPKYEIKTNKGTRVLTSPWHPFFVITQDLKIVEKRADELR
EGDMLVGGMPSDDDYEFLLDYWLAGFIAGDGSIDKYRSHVKGHEYVYDRLRIYDYTTETL
GIINDHLEKTFGKRYSLQRDRNIHYIDIKAKGITSHYIELLRGITNGIPQPILKEGRNAV
LSFITGLFDAEGHVNSKPGVELGMVNRKLIEDITYYLNSLGIKARMRKKPRKDGVDYVMH
VEEYSSLLRFYELIGKNLQNSEKRIKLEELLSKHNGGSFGLTLSFEDFKAWSSKYGVEFK
TNGSQTLAIIKNEKVSLGQWHRRGRVSKAVLVKMLRKLYDTTKSEDVKRMLHLIEGLEVV
KEINVTNEPKTFYDLTVERYQNYLAGENGMVFVHNTGLNFSKLRPEGDLVGTTTGAASGP
VSFMHLIDAVSDVIKQGGVRRGANMGILEVWHPDIEKFIHAKEKNTGTNVLSNFNISVGL
WEDFWEALKEGKRYPLINPRTGEKVKEIDPKSLFEELAYMAWAKADPGVVFFDVINRRNV
LEPAKGEKIRATNPCVVGDTRVLTPEGYIKAEELFSLAKERGKKEAVAVEGIAEEGEPYA
YSVEVLLPGEEEVKYETVHGKALAIADPVAVPAYVWKVGKKKVARVRTKQGYEITATLDH
RLMTSEGWKEVGELKPGDEILLPRFEIEEDFGSESIGEDLAFVLGWFIGDGYLNVNDKRA
WFYFNAEKEEDIAWKIREILAKHFGIKAEPHRYGNQIKLGVRGEAYRWLESIMGSNEKRV
PEIIYRLKPREIAAFLRGLFSADGYVDNDNAVRLTSKDRGLLRDVQDLLLLFGILSKIYE
RPYSSEFKYTTKDGEERTYRAEGYYELVIANYSRKLFAEKIGFEGYKMEKLSLQKTKIDE
PVVTVESVEVLGEEIVYDFTVPEHHSYISNGFMSHNCGEEPLYEYESCNLASINLAKFVK
YDDEGKPYFDWDEYAYVIQKVAKYLDNAIDVNKFPLPEIDRNTKLTRRIGVGMMGLADAL
FKLGIPYNSKEGFDFMRKATEYLTFYAYKRSVEAAKERGPFPLYEKTRYKDGELPVEGFY
HREIWNLPWDELVEEIKKYGVRNGMVTTCPPTGSVSMIADTSSGIEPIFALVYKKSVTVG
EFYYVDPVFEAELKKRGLWSDEILKKISDNYGSVQGLEEIPEDMQRVFVTAMDIHWLDHI
LAQANIQLWLTDSASKTINMPNDATVEDVKAAYLLAYKLGCKGVTVYRDGSLSVQVYSVE
GEKKKRVPAKPSDYAVEKLKTIVEAEPWLSRFINVEAILNGTNGKEKSAQAGGLTFSVSH
VSAVKPAHEHSHHAKRPDIPEEKIRELLGVAYCPVCYEKDGELVELRMESGCATCPRCGW
SKCVIS
NT seq 5241 nt   +upstreamnt  +downstreamnt
atgcctgttgaaaaagtgatgaaacgagacggtagaattgtgccctttgataaggagcgt
ataaggtgggctatacagagggcaatgcttgaagtcggcgtcagggatgagaagcttctc
aacagggttgtcaggcgcgttgtgaggagggtaaacgagctctatgacggccagattccg
aacatagagaacatacaggacatagtcgagcttgagctcatgcgcgctggtctttttgat
gtggcaaaggcctacatcctctaccgcaagaagaaggccgaaatccgtgaagaaaagaag
aagatactcaacaaggacaagctggatgagattgacaagcgcttttccctcaacgcactc
cgtgttctcgcttcccgctacctgataaagaacgagaagggagagataatcgagagcccg
agggagcttttcgagagggttgcaatccttgcagtcatcccagacatcctctacgacgag
agggtctttgacaaaaacggcggacacgaacaagacgttagtgccattgaaagataccgc
gaaaacctcgatgagtacgacggaaagttctcgataggcaggttcaggctcaacaagtgg
cactttgagcggctcctcaacctctaccgcgagctggccgagaagggccagatgaagctc
cccatagacgaagtcctgaagatgctcgagaacggcgcttttgacaattacgaggacgag
atagaggagtacttcaggctgatgaccgggcagtacttcatgccaaacacaccagccctc
atcaactcaggaaggccccttggaatgctctcggcctgcttcgtcgtcccgattgaagac
gatatggagagcatcatgaaagcggcccacgacgtggcgatgatacagaaggccggaggg
ggatgtatagacggaaacgccaaaataatctttgaaaacgacggcgaagaacacatcatg
acgatggccgagatgtacgagaggtacaaagacctcggcgagttctatgacccggagtac
aaccgctgggggataaacgtcgaagaagttccagtatacgtgaaatcctttgacccatca
acaaaggagatcaccaaaggaaaggtgaaagtcatttggaagtacgagctcggcgaggat
gttcctaagtacgagataaaaactaacaagggtacaagagttctaacgtcgccatggcat
ccgttctttgttatcacacaggacctcaagattgttgagaagagggccgatgaactcaga
gaaggggatatgctagttggcggaatgccaagtgatgatgactatgagttccttttggat
tactggctcgcgggattcatagcaggggacgggagcatagacaaataccgctctcacgtc
aaaggccacgagtacgtttatgacaggctaaggatatacgactacacaacagaaacactc
gggataatcaatgatcatcttgaaaaaacctttggaaagaggtacagccttcagagggac
agaaacatccattacattgacataaaagcaaaggggataacatcccactatatagagctt
ctgagaggtattacaaatgggattccacaaccgatactcaaagaaggcagaaatgcagta
ttatcgttcataaccggcctctttgacgccgaaggacacgttaacagcaaacctggtgtt
gaacttggaatggtgaacaggaagctgatagaggacatcacatactacctcaattccctt
gggataaaagccaggatgcggaagaagccgagaaaggacggcgttgattacgtcatgcat
gttgaggagtactcctcactcctcaggttctacgaactcataggaaagaaccttcagaac
tctgagaagagaataaagcttgaggaacttctcagcaaacataatggtggatcatttggt
cttacactcagctttgaagattttaaggcatggagctcaaagtacggcgttgagttcaag
acaaacggcagtcagacattggctataataaagaacgaaaaggtatctcttggtcagtgg
cacaggagaggacgcgtttccaaggccgttctagtgaagatgctgaggaaactctacgac
actacaaagagcgaggacgtcaaaaggatgctccacctcattgaaggcctcgaagtcgtt
aaggagatcaacgtcacgaacgagccaaagaccttctacgaccttacggttgagaggtac
cagaattatctcgctggagaaaacgggatggtctttgtccacaataccggcctcaacttc
tcgaagctccgtcccgagggagaccttgtcgggaccaccactggagcggcgagcggtcca
gtctcgttcatgcacctcattgatgccgtcagcgacgtcataaagcaggggggagtgaga
agaggggccaacatgggcatcctcgaggtctggcacccagacatagagaagttcatccac
gcaaaggagaagaacacgggaaccaacgtcctcagcaacttcaacataagcgttggatta
tgggaggacttctgggaggccctcaaagagggcaagcgctacccgctcatcaacccgcgc
accggtgaaaaggtcaaggagatcgaccccaagagcctgtttgaagagctggcctatatg
gcctgggccaaggccgacccgggtgttgtcttcttcgacgtcatcaacaggaggaacgtc
ctggagcctgcaaagggtgaaaaaatccgcgccaccaacccgtgtgtcgtcggggacacg
agggttctcacgcctgaaggatacatcaaggcagaggaactgttcagcctcgcgaaggag
aggggtaagaaggaggccgttgcagtagagggaatagcggaggagggagagccctacgcc
tactcagtggaggttctcctgcccggtgaggaggaagtcaagtacgagaccgtccatgga
aaggccctcgcaatagcagaccccgtggccgtcccggcctacgtctggaaggtcggaaag
aagaaggtcgcaagggtcagaacaaagcagggctacgagataacggcgacactcgaccac
aggcttatgacttccgagggctggaaagaagttggagagctgaagccgggagacgagatc
ctccttccacgctttgaaatagaggaggacttcggaagcgagagcataggagaagacctc
gccttcgtcctcggatggttcataggggacggctacctcaacgttaacgacaagagggct
tggttctacttcaacgcagagaaagaggaagatatcgcgtggaaaatcagggagatatta
gcgaagcacttcggcattaaagccgagccccaccgctacggcaaccagataaagctcggc
gtgaggggagaagcctacaggtggcttgagagcatcatgggaagcaatgagaagagagta
ccagagataatctacaggctcaagccgagggaaatagcggcgttcctcaggggactcttc
agtgccgacggctacgttgacaacgacaatgcggtaaggcttacatcgaaggacaggggg
ctcctcagggatgttcaggaccttctcctgctctttggaatactctccaagatatacgag
agaccttattcaagcgagttcaagtacacgaccaaggatggagaggagagaacctacagg
gcggagggctactacgagctcgtcatagctaactacagcaggaagctcttcgccgagaag
ataggcttcgagggctacaagatggagaagctgagccttcagaaaaccaagatcgacgag
cctgtggtcaccgtcgagagtgttgaagtccttggcgaggaaatcgtctacgacttcaca
gttccagagcatcacagctacataagcaacggcttcatgagccacaactgtggggaagag
ccgctctacgagtacgaatcctgtaatctggcctccataaatctcgcaaagttcgtaaag
tacgacgacgaaggcaagccgtacttcgactgggacgagtacgcctacgtcattcagaaa
gtcgcaaagtatctcgacaacgccatcgatgtcaacaagttcccgctcccggagatagac
aggaacaccaagctcacgaggaggatcggagttggcatgatgggccttgccgatgcgctc
ttcaagctcggcattccctacaacagcaaagagggcttcgacttcatgaggaaggccacc
gagtacctgaccttctacgcctacaagaggagcgttgaagcggcaaaagaacgcggtccg
ttcccgctctacgagaagaccaggtataaggacggagaactgcccgtcgagggcttctac
cacagggagatatggaacctgccctgggacgaactcgttgaggagattaaaaagtacggc
gtgaggaacggaatggtgaccacctgcccgccgaccggaagcgtcagcatgatagccgac
acctccagcggaatcgagcctatattcgccctcgtctacaagaagagcgtcaccgttgga
gagttctactacgttgaccccgtgtttgaagcagagctcaagaagcgcgggctctggagt
gatgagatactcaagaagataagcgacaactacggttcagttcaaggccttgaggaaatt
ccagaggacatgcagagggtctttgtaacggccatggacatccactggctcgaccacatt
ctagctcaagccaacatccagctctggctgactgattccgccagcaagacgataaacatg
ccgaacgatgccaccgtcgaggacgtgaaagctgcctacctgctcgcctacaagctcggc
tgtaagggcgtaaccgtctaccgcgacggctcgctgtcggttcaggtctacagcgtcgag
ggtgaaaagaagaagagggttcccgcgaagccgagcgactacgccgtcgagaagctgaag
acgatagtagaggccgagccgtggctatcgcgcttcatcaacgtcgaggccatccttaac
gggacgaacggaaaggagaagagcgcccaggctggagggctgacattctcggtttcccac
gtctccgccgtaaaacccgcccacgagcactcgcaccacgccaagaggccggatatccca
gaggagaagataagggagctcctcggagttgcctactgcccggtctgctacgagaaggac
ggcgagctcgttgagctcaggatggagagcggctgcgcaacctgcccgcgctgcggctgg
agcaagtgcgtcataagctga

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