Thiothrix lacustris: RCF98_12810
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Entry
RCF98_12810 CDS
T09396
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
tlc
Thiothrix lacustris
Pathway
tlc00230
Purine metabolism
tlc01100
Metabolic pathways
tlc01110
Biosynthesis of secondary metabolites
Module
tlc_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
tlc00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
RCF98_12810 (purL)
Enzymes [BR:
tlc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
RCF98_12810 (purL)
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GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
WML89849
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Position
2605555..2609445
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AA seq
1296 aa
AA seq
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MLIFPGSVALSEFRRNKLLNALQAAVPAVSGVQAEYLHFVRTSREPSADELARLQALLTY
EETQGSHDFSGTLFLVTPRAGTISPWSSKASDIAHNCGLTMVERVERGVAYDVQTTASLT
TAERGAIAALLHDRMTEMVLADTQDAIVLFSEAEPAPLRYVDISDDAAAALAKANTDWGL
ALSPDEIDYLAENYAELQRNPTDVELMMFAQANSEHCRHKIFNADWIIDGKEQPKSLFAM
IRNTHAHAPEGILSAYHDNASVIEGPLATRFLTDVKTGEYHYTNEPVHILMKVETHNHPT
AISPFAGAATGSGGEIRDEGATGNGSKPKAGLSGFSVSNLRIPGYEQPWEHDFGKPGRIV
SALDIMLEGPIGAAAFNNEFGRPNITGYFRTFEMQAPGAKGTELRGYHKPIMIAGGMGNI
RENNINKNPLPEGTPIIVLGGPAMLIGLGGGAASSMASGTSAENLDFASVQRGNPEMQRR
CQEVIDRCVALGNENPILSIHDVGAGGISNAIPEIVNDAGRGGRFELRAVPNAELGMAPM
EIWSNEAQERYVLAIAEDRLDTFRALCDRERAVYAVVGSATIEQQLLVGDSLFDNNPVNL
PMNVLLGKPPKMLRDVHHQTFHKPEIDLSGIELPEAIERVLRLPTVASKAFLITIGDRSV
TGMVTRDQMVGAWQVPVADVAVTSSDYSTNFGEAMAMGERTPIALVNPAASGRMAIGEAL
TNIAAADIADIRNIRLSANWMAAAGYPGEDAALFDTVKAVGEELCPRLGLAIPVGKDSLS
MKTVWQQDGEDREMAAPLSLIVTAFSPVQDIRKTLTPALRTDVGDTDLILVDLGKGRNRL
AASALMQVYGQVGHHAPDVDNPDALKAFFDTVQDLRAENLIQAYHDRADGGLLATLAEMS
FAGHVGVTACIGQISGQLLPALFNEELGAVLQIRHCDTDSVLEAFREAGLAHCTHVIGEL
NDSDELVLTFANKEVYRAPRATLQKVWAETSYRMQALRDNADCAAQEFERLDDVQDPGLP
FTPTFDPDEDVAAPYIRTGVRPAVAVLREQGVNGQVEMAAAFDRAGFKAVDVHMTDIISG
RVSLKDFKGLVACGGFSYGDVLGAGGGWAKTILMNPQASDEFAAFFARQDSFGLGVCNGC
QMFSQLRGMIPGAAHWPRFYRNRSEQFEARYSAVEVLESPSLFLKGMAGSKMPITVAHGE
GRAVFDTATAEGMLAEGLVGLRYVDNRGNATEHYPENPNGSPLGITGVTTADGRFTIMMP
HPERLFRAVQHSWKPDEMGEDGAWLRMFRNARVWVG
NT seq
3891 nt
NT seq
+upstream
nt +downstream
nt
atgctgatcttccccggtagcgttgccctttccgaattccgccgcaacaagctgttaaat
gcgctgcaagcggctgtgcctgcggtctctggtgtacaagccgaatacctccatttcgtg
cgcacctcgcgtgagccgagtgctgacgaactcgcccgtttgcaggcattgctgacctat
gaagaaacgcaaggcagccacgatttcagcggaacgctgttcctcgtcaccccgcgtgcc
gggacgatttccccttggtcaagcaaggccagcgacatcgcccacaactgcggcctgacg
atggtggaacgggtagagcgcggtgtcgcctacgacgtacaaaccaccgcgtcactcacc
accgccgagcgtggcgcaatcgctgcgctgttgcacgaccgcatgaccgaaatggtgctg
gcagacacgcaagatgcgattgtcctgttcagcgaagccgagcctgcgccattgcgctac
gtcgacatttcggacgacgcagcggcggcactcgccaaagccaacactgactggggtctg
gcactttccccggatgaaatcgactacctcgcggaaaattacgccgaactccagcgcaac
cccaccgacgtagaattgatgatgttcgcgcaagccaattccgaacattgccgccataaa
atcttcaacgccgattggattatcgacggtaaagaacagcccaaatcgctgtttgccatg
atccgcaacacccacgcgcacgcgcccgaaggcatcctctccgcctaccatgacaacgcc
tccgtcatcgaaggcccgttggcaacgcgctttttgaccgacgtaaaaaccggcgaatac
cactacaccaacgaacctgttcacatcctgatgaaggtggaaacccacaaccaccccacc
gcgatttccccgttcgcaggcgcggcgacaggttcgggcggcgaaatccgcgacgaaggc
gccactggcaacggctccaagcccaaagcaggtttgagcggcttctcggtgtccaacctg
cgcattcccggctatgaacagccgtgggaacacgatttcggtaaaccggggcgcatcgtt
tccgcgctcgacatcatgctcgaagggcccattggcgcagcagcgttcaataacgaattc
ggccgccccaatatcaccggctacttccgcacctttgaaatgcaagcgcccggcgcgaag
ggcacggaactgcgcggctaccacaagcccattatgattgcgggcggcatgggcaatatc
cgcgaaaacaacatcaacaaaaacccgctgccggaaggcacgccgatcatcgtcctcggt
ggccccgcgatgctgattggtctgggtggcggcgcggcttcctcaatggcgagcggcacc
agtgcggaaaatctcgacttcgcttccgtgcagcgtggcaaccctgaaatgcaacgccgt
tgccaagaagtcatcgaccgctgcgtggcgctgggcaatgaaaacccgatcctctcgatt
cacgacgtgggcgcaggcggtatttccaacgccattcccgaaatcgtcaacgatgccgga
cgtggcggacgctttgaactccgcgccgttcccaacgctgaactcggcatggcaccaatg
gaaatctggagcaacgaagcgcaagaacgctacgtactcgccattgccgaagaccgcctc
gacacgttccgcgccttgtgtgaccgcgaacgtgccgtgtacgcggtggtcggtagcgca
acgattgaacaacaattgctggttggcgattccctgtttgacaacaatccggtgaatttg
ccgatgaacgtgctgctcggcaaaccgccgaaaatgctgcgcgatgtgcatcaccagacc
ttccacaaaccggaaatagacctgagtggcattgaacttcctgaggcgattgagcgcgtg
ttgcgcttgccgacggtagcctccaaagccttcctcatcaccattggcgaccgctcggtc
acgggcatggtcacacgcgaccagatggtcggtgcatggcaagtgccagtggcggatgtg
gcggtaacgtccagcgattacagcacaaatttcggcgaagccatggcgatgggtgaacgc
accccgattgcgctggtgaacccggcagcctccgggcgcatggcgattggtgaagcgctt
accaatattgcggcggcggatattgctgacattcgcaatattcgtctgtcggccaactgg
atggcggcggcgggctaccccggcgaagatgccgcgctgtttgacaccgtgaaagcggtc
ggcgaagagctgtgcccacgtttaggtttggcgattccggtcggcaaagattccttgtca
atgaaaacggtctggcagcaggacggcgaagatcgcgaaatggctgcccctttgtcactg
atcgtgaccgcattttccccggtgcaggacatccgcaagaccctgaccccagcgttgcgc
actgacgtgggtgacactgacctgattctggttgacctcggtaaaggccgcaaccgcttg
gcagcttctgcgctcatgcaagtgtacgggcaagtcgggcatcacgcgccggatgtggat
aaccccgatgcgctcaaagccttcttcgacaccgtgcaggatttgcgtgctgaaaacctg
attcaggcatatcacgaccgtgcggatggcggtttgctggcaacgttggcagaaatgagt
ttcgccgggcatgtgggcgtgacggcttgcattgggcagatcagtgggcagctattgcca
gcgttgttcaatgaagaactcggtgcggtgctgcaaattcgtcattgtgatacggattct
gtgttggaagccttccgcgaagccggtttggcgcattgcacccacgtgattggcgaactc
aacgacagcgacgaactggtgctgacctttgccaacaaggaagtctatcgcgccccgcgt
gcgaccttgcagaaagtttgggcagaaaccagctaccggatgcaggcgttgcgtgacaat
gccgattgcgccgcgcaagagtttgagcgtttggatgatgtgcaagatcccggtctgccg
tttaccccgaccttcgacccggatgaggatgtggcagcgccgtatatccgaaccggcgtg
cgccctgcggtggcagtgctgcgcgaacagggcgtgaacggtcaggtggaaatggcggca
gcgttcgaccgtgccggtttcaaggcggttgacgtacacatgaccgacattatcagcggg
cgcgttagcctgaaagatttcaaaggcttggtggcgtgtggcggcttctcttacggcgac
gtgttgggagcaggcggcggttgggcgaaaaccatcctgatgaacccgcaagccagcgat
gaatttgcagccttttttgcgcggcaagattctttcgggctgggcgtgtgcaatggctgc
cagatgttctcgcaattgcgcggcatgatccccggtgcggcgcattggccacgtttctac
cgcaaccgttccgaacagttcgaggcgcgttattcagcggtcgaggtgttggagtcgccg
tcattgttcctgaaaggtatggcaggctcgaagatgccgattacggtggcgcatggcgaa
ggccgggcagtgtttgatactgcgacggctgaaggtatgttggcggaagggctggtgggc
ttgcgttacgtggataatcgcggcaatgccaccgagcattacccggaaaacccgaacggt
tcgccgttggggattacgggcgttaccaccgctgatgggcgcttcaccatcatgatgccg
cacccagaacgcttgttccgcgccgtgcagcactcgtggaaaccggatgagatgggggaa
gatggcgcgtggttgcggatgttccgtaatgcgcgggtttgggtggggtag
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