Pseudothermotoga lettingae: Tlet_1784
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Entry
Tlet_1784 CDS
T00618
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tle
Pseudothermotoga lettingae
Pathway
tle00300
Lysine biosynthesis
tle00550
Peptidoglycan biosynthesis
tle01100
Metabolic pathways
tle01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tle00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Tlet_1784
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Tlet_1784
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Tlet_1784
Enzymes [BR:
tle01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Tlet_1784
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
PF1197-like_C
RPN6_C_helix
DUF2281
Motif
Other DBs
NCBI-ProteinID:
ABV34338
UniProt:
A8F854
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All DBs
Position
1854259..1855527
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AA seq
422 aa
AA seq
DB search
MFENSRFVVDSRQVTPGCVFVAIKGEKTDGHFYANEAINKGAAYVVAEKKLQHIPEEKLI
TVNDTIEFLLSNAREKLKKHNPVVIGITGSNGKTTTKELLYQLLGKDRAFRNPGNLNTEI
GLPLSILNEYNAEKFAILEMAMNKFGDIARLCQIAMPHVAILLNVGTAHRGIAGNQEMIL
RGKLQLIENMQKNGTAIVLYDKKLLDRISLKPMVTFGYKKGDYQLVDYCYIDFSTKAFYK
TPREQLIFNLKSIWNAGQLTNISAVLAALDILGIDCNKNILENFTPVAGRFRVMNCNGIY
VVDDTYNASIESFETAVETIKKLGKRSFAVVGSIKEQGKYSIETHRKLGEILEKLDGVVV
YNVDNEIEIMNCSKKIFASNSATEISDFLKRILIPGDVVLFKASRSVQIEKVLQIYTEEI
RC
NT seq
1269 nt
NT seq
+upstream
nt +downstream
nt
gtgtttgagaattctcgttttgtcgttgattcaaggcaagttacccccggatgtgttttc
gtagccattaaaggtgaaaaaactgatggacacttttacgccaatgaagcaattaacaaa
ggtgctgcttatgtcgttgctgaaaaaaaactacaacatattccagaagaaaaattgata
actgtcaatgacacaattgagtttttgctcagcaatgccagagaaaaattaaaaaaacat
aatccagttgtgataggtataacaggttcaaacggaaaaaccaccacgaaagaactcctc
tatcagctcttgggaaaagacagggcttttcgtaatccaggaaatttgaacacggagatc
ggtttgccactatcgattctcaatgaatacaatgcggagaaattcgctattttagaaatg
gctatgaataaatttggagatattgcaagattatgccaaatagccatgcctcacgtggca
attttgctgaatgttggaacagcacatcgtggaatagcaggaaatcaggaaatgatattg
agaggaaaactccaattaatcgagaatatgcaaaaaaatggaacagccatagttttgtat
gataaaaaactgctggatagaatttcattgaaacctatggtaacttttggctataaaaaa
ggagattatcaacttgtcgattattgctatattgatttctcaacgaaagccttctacaaa
accccaagagagcagctaattttcaacctcaaatcaatctggaatgccggtcagctaaca
aatatatcagcagttttagccgcactggacattcttggaatagactgtaataaaaacatc
ctggaaaactttacgcctgtggctggaagattcagggtaatgaattgcaatggaatttat
gtggtggatgacacttataatgcaagcatagagtcgtttgaaacagccgttgaaacaata
aagaagcttggtaaaagatcatttgctgtagttggttcaattaaagaacagggaaaatac
tcaattgaaacacacaggaaacttggcgagattctcgaaaaattagatggtgttgtggtt
tacaatgtcgataatgagatagaaatcatgaactgttcaaaaaaaatttttgcaagcaac
agcgcaacagaaatctctgattttttgaaaagaatcctgatacccggcgatgtagtttta
ttcaaagcatcaaggtcagttcaaatagagaaagttttgcaaatatatacggaggagatt
agatgttga
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