KEGG   Thiomicrorhabdus lithotrophica: NR989_09340
Entry
NR989_09340       CDS       T09486                                 
Symbol
purH
Name
(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
tlh  Thiomicrorhabdus lithotrophica
Pathway
tlh00230  Purine metabolism
tlh00670  One carbon pool by folate
tlh01100  Metabolic pathways
tlh01110  Biosynthesis of secondary metabolites
Module
tlh_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:tlh00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    NR989_09340 (purH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    NR989_09340 (purH)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:tlh04147]
    NR989_09340 (purH)
Enzymes [BR:tlh01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     NR989_09340 (purH)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     NR989_09340 (purH)
Exosome [BR:tlh04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   NR989_09340 (purH)
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS
Other DBs
NCBI-ProteinID: WEJ62210
LinkDB
Position
1981993..1983555
AA seq 520 aa
MKPVRRALISVSDKTGILEFAESLTAMNVAILSTGGTYKVLSEAGLPVTEVSEYTGFPEM
MDGRVKTLHPKIHGGLLGRRGTDDAIMAEHGIDAIDMVVVNLYPFEATVANPDCKLEDAV
ENIDIGGPTMLRSAAKNHKDVAVVTDPADYGRILEEMQSNDGQLAHATRFDLAIKTFEQT
SRYDGAISNYFGKMFSSDEADNFPRTYNTQFVKKQTMRYGENPHQNAAFYTERNPSEASI
STATQLQGKELSFNNIADTDAALELVKTFSETACVIVKHANPCGVSIGATQFEAYDRAYK
TDPTSAFGGIIAFNTELDAKTAQAIVDRQFVEVIIAPTVSAEAVAIVEAKKNVRLLACGE
LGAQQTAHDFKRVTGGLLVQDRDLGMVEEADLKVVTKKAPTAEQMKDLMFAWKVAKFVKS
NAIVYVKDGMTIGVGAGQMSRVYSAKIAGIKAADEGLEVPGSVMASDAFFPFRDGIDAAA
EAGITAVIHPGGSMRDQEVIDAADEHGIAMVFTGMRHFKH
NT seq 1563 nt   +upstreamnt  +downstreamnt
atgaaaccagtacgtcgcgccctaatcagcgtttctgataagacaggcattttagaattt
gctgaatcgttaactgcaatgaacgttgctattctgtctacaggcggaacttataaagtt
ctttctgaagcaggtcttcctgttactgaagtttcagaatatacaggttttccagagatg
atggacggccgtgtaaaaacccttcatcctaaaattcacggtggactactaggacgcaga
ggaaccgatgatgccatcatggcagagcacggtattgatgcaattgatatggttgtagtt
aacctttatccttttgaagcaacggttgctaacccagactgcaagcttgaagatgctgtt
gaaaacatcgatatcggtggaccaaccatgcttcgttcagccgcaaaaaaccataaagat
gttgctgtggtaacagacccagcagattacggtcgtattcttgaagaaatgcaatcaaac
gatgggcaacttgcacacgcaacacgctttgatttagcgattaaaacattcgaacaaact
tcacgctacgacggcgctatctcaaactacttcggcaagatgtttagctctgacgaagca
gacaacttccctcgcacgtacaacacgcagtttgttaaaaagcagacgatgcgatacggt
gaaaaccctcatcagaatgccgcattctatacagagcgtaatccttctgaagcgtcaatt
tcaacagctactcagcttcaaggtaaagaactttctttcaacaacattgctgacactgat
gcagcattagagttagttaagaccttctctgaaacagcttgtgtcattgttaaacacgca
aacccttgtggcgtatcaatcggtgcgactcaatttgaagcttatgaccgagcttataaa
acagatccaacttctgcttttggtggcatcattgcattcaacactgagctagatgctaaa
acagctcaagcaattgttgatcgtcagtttgttgaagtcattattgctccaactgtttca
gctgaagcggttgccattgtagaagcgaagaaaaacgtacgtttattagcatgtggtgaa
ttaggtgcacaacaaacggcgcatgactttaagcgtgtaacaggtggcctacttgttcaa
gaccgtgacctgggcatggtagaggaagcagatcttaaagtcgtgactaaaaaagcccca
actgcagaacagatgaaagatctcatgtttgcatggaaagtggcaaagtttgttaaatct
aacgcgattgtttacgttaaagacggtatgacaatcggtgtaggtgcaggtcaaatgagt
cgtgtttactctgcaaaaattgcagggattaaagcagccgatgaaggattagaagtgcca
ggttccgttatggcatcggatgcattcttcccattccgtgacggtattgatgcggcagct
gaagcaggcattactgcggtaatccatcctggtggttcaatgcgcgatcaagaagtgatt
gatgcagcagatgagcatgggatagcaatggtgttcacaggaatgagacacttcaaacac
taa

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