Thermotoga maritima MSB8: TM0259
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Entry
TM0259 CDS
T00022
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
tma
Thermotoga maritima MSB8
Pathway
tma00470
D-Amino acid metabolism
tma00550
Peptidoglycan biosynthesis
tma01100
Metabolic pathways
tma01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tma00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
TM0259
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TM0259
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TM0259
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
tma01011
]
TM0259
Enzymes [BR:
tma01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
TM0259
Peptidoglycan biosynthesis and degradation proteins [BR:
tma01011
]
Precursor biosynthesis
Amino acid ligase
TM0259
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp_3
ATP-grasp_4
ATP-grasp
CPSase_L_D2
RimK
ATP-grasp_LDMS
GARS_A
Motif
Other DBs
NCBI-ProteinID:
AAD35347
UniProt:
P46805
LinkDB
All DBs
Position
268747..269658
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AA seq
303 aa
AA seq
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MRVALLMGGVSREREISLRSGERVKKALEKLGYEHTVFDVREDFLKKVDQLKSFDVVFNV
LHGTFGEDGTLQAILDFLGIRYTGSDAFSSMICFDKLVTYRFLKGTVEIPDFVEIKEFMK
TSPLGYPCVVKPRREGSSIGVFVCESDEEFQHALKEDLPRYGSVIVQKYIPGREMTVSIL
ETEKGFEILPVLELRPKRRFYDYVAKYTKGETEFILPAPLNPSEERLVKEMALKAFVEAG
CRGFGRVDGIFSDGRFYFLEINTVPGLTETSDLPASAKAGGIEFEELVEIILKSAFLKEG
VRV
NT seq
912 nt
NT seq
+upstream
nt +downstream
nt
gtgagagtggctctcctgatgggaggagtgtcgagggaaagggaaatctctctgagaagc
ggagaaagggtaaaaaaggctcttgaaaaactcgggtatgaacacaccgtttttgacgtt
agagaagattttctcaagaaagtggatcagttgaaaagttttgatgtggtcttcaacgtt
ctccatggaactttcggtgaggatggaacgcttcaggcaattctggattttttggggatc
agatacaccgggtccgatgcgttttcaagcatgatatgttttgataaactcgtgacttac
aggtttttaaagggcaccgtcgagatacctgattttgtggagatcaaggaattcatgaaa
acttctccccttgggtatccctgtgtggtaaaaccgaggagagagggttcaagcatagga
gtgttcgtttgtgaatcggatgaagagtttcaacacgcgctcaaggaagatttaccacga
tatgggagtgtgattgttcaaaagtacatccccggcagggaaatgactgtgtctatttta
gaaacggaaaagggcttcgaaattcttcccgttcttgagttgcgaccaaagcgtcgtttc
tacgattacgttgcgaagtacacgaaaggtgaaacggagttcattcttcctgctcctttg
aatccttcagaagaacgccttgtcaaggaaatggctctcaaagcgtttgtagaagctggt
tgcagaggttttgggagggtggatggtattttcagcgatggcaggttctactttctggaa
atcaacacggtaccgggtctaacggaaaccagtgatctcccagcgagcgcgaaagcggga
ggaatcgagttcgaggaactcgttgagatcatcttaaagagcgcttttttgaaagaaggg
gtgagagtatga
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