Tenacibaculum maritimum: MARIT_1352
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Entry
MARIT_1352 CDS
T05240
Symbol
thrA
Name
(GenBank) Bifunctional enzyme: aspartate kinase/homoserine dehydrogenase
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
tmar
Tenacibaculum maritimum
Pathway
tmar00260
Glycine, serine and threonine metabolism
tmar00261
Monobactam biosynthesis
tmar00270
Cysteine and methionine metabolism
tmar00300
Lysine biosynthesis
tmar01100
Metabolic pathways
tmar01110
Biosynthesis of secondary metabolites
tmar01120
Microbial metabolism in diverse environments
tmar01230
Biosynthesis of amino acids
Module
tmar_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
tmar_M00527
Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
tmar00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
MARIT_1352 (thrA)
00270 Cysteine and methionine metabolism
MARIT_1352 (thrA)
00300 Lysine biosynthesis
MARIT_1352 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
MARIT_1352 (thrA)
Enzymes [BR:
tmar01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
MARIT_1352 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
MARIT_1352 (thrA)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
ACT_7
NAD_binding_3
ACT
ELFV_dehydrog
TAFII28
Motif
Other DBs
NCBI-ProteinID:
SFZ81941
UniProt:
A0A2H1E9A0
LinkDB
All DBs
Position
complement(1433747..1436188)
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AA seq
813 aa
AA seq
DB search
MKVLKFGGSSVANSQNIQKVIQIISNASLHEKIIVVVSAFGKTTNKLIEASQKASQKDQG
YIALLKEVEELHMKVVKELIPIIEQSSVLSQAKRLFNHLETLLEGCYLLQEITPKTLATI
SGFGELLSSYIISEVAKNKLNACYKDSRELIITSNLYEKAKVNFHKTTNNCQGYFPQNKY
QVTILPGFIAATENGQTTTLGRGGSDYSAAIYAAALNASELQIWTDVSGMYTANPNLVKQ
AFPIPHISYQEAMELSHFGAKVIYPPTIQPVLEKQIPIIIKNTFDPDHEGTRIALKTATK
NPVKGISHIENITLLTLEGSGMVGVSGISKRLFETLSSENINVVLITQASSEHSICIGIY
DEDAQKATEHINKAFAFEIEQHKIAPIIIEKQLAIIALVGDNMKSHQGLSGQMFSALGKN
NVNIRAIAQGASEKNISAVINSVDAKKALNTLHEQFFEEKIKQLHLFVTGVGNVGERFLS
QINQQSTYLKKHLKLNIRVIGISNSKKMIFDENGIDLSTWKEALNKGESNSLTGFFSKIK
LLNLRNSVFVDNTANLQVSETYENYLSHNIGVVTCNKIACASKLENYKNLKRISRKYNAP
FLFETNVGAGLPIIDTLKNLIASGDRILKIQAVLSGSLNFVFNNFNETTTFHHVVSTAQK
EGYTEPDPKIDLSGIDVARKILILARESGFELELSDIQNDSFLPEKSLNTTTNHDFYNSL
TEFEPHFQKIYQEASHQNKRLKYVAEFINGKAKVGLQHIPPKHPFYNLEGSDNIVLFYTE
RYPVNPLIIKGAGAGADVTASGIFADVIRIGNN
NT seq
2442 nt
NT seq
+upstream
nt +downstream
nt
atgaaagtcttaaaattcggaggttcatcagtagccaatagtcaaaatattcaaaaagta
attcaaattataagcaatgcttctttacacgaaaaaataatagtagtagtctctgctttt
ggaaaaacaaccaataaattaatagaagcttctcaaaaagcttcccaaaaagaccaaggg
tacatcgctttactaaaagaggtggaagaacttcatatgaaagtcgttaaagagttgatt
cctatcattgaacagagtagcgtattaagccaagctaaaagattattcaatcatttagaa
actttattagaagggtgctatttactacaagaaataacgccaaagacattagctactatc
agtggttttggagaattactatcttcttatatcatttcagaagttgctaaaaacaaatta
aatgcttgttataaagatagtagagaacttatcattacctctaatttatatgaaaaagca
aaggtaaacttccataaaaccactaataattgccaaggatatttccctcaaaataaatac
caggtaaccattcttcctggttttattgctgctactgaaaacgggcaaacaactactcta
ggtcgcggaggatctgattattctgctgctatttacgcagctgctttgaatgcttctgaa
ttgcaaatttggacagacgttagcggaatgtacactgcaaatcctaatcttgtaaaacaa
gcattcccgattcctcatatatcttaccaagaagccatggagctatctcattttggagca
aaagtaatttatccacctactattcaacctgtattagaaaaacagattccaataattata
aaaaatacttttgatcctgatcatgaggggactcgtattgccttaaaaaccgctactaaa
aaccccgtaaaaggaataagccatatagaaaacatcactttactcactttagaaggaagt
ggtatggttggtgtttctggtatctcgaaacgcttatttgaaaccctatcttctgaaaat
atcaatgtggtattaattactcaagcttcttcagaacattcaatttgtattggtatttat
gatgaagatgctcaaaaagcgactgaacatattaacaaggcttttgcttttgaaatcgaa
cagcataaaatagctcctataatcatcgagaaacaattagccatcattgcattagttggt
gacaatatgaaaagtcatcaaggtttgagcgggcaaatgtttagcgctctcggcaaaaat
aacgtaaacatcagagcaattgctcagggcgcttctgaaaaaaacatttcagcagttatc
aatagcgtcgatgctaaaaaagcattaaatacattacatgagcaattctttgaggaaaaa
ataaaacaactacacctttttgtcacaggagtaggaaatgtaggagaacgatttctttct
caaatcaatcaacagtcaacttatttaaaaaaacatttaaagttaaacattagagttatt
ggaatttcaaattctaaaaaaatgatctttgatgaaaatggaattgatttaagtacttgg
aaggaagctttaaataaaggcgaatctaatagtttaacaggcttcttcagtaaaataaaa
cttcttaatttacgtaactctgtgtttgttgataatactgctaatcttcaagtttctgaa
acctacgaaaactatcttagccataatataggtgttgttacttgtaataaaatagcctgt
gcttctaagctggaaaactataaaaacctaaaaagaatttctaggaaatacaacgctcct
tttttgtttgaaacgaatgttggtgctgggttaccaattatagacacactaaaaaacctt
atcgcttcaggagatagaattcttaaaattcaagcagttttatcaggaagtttgaatttt
gtttttaataattttaatgaaactactacctttcatcatgtcgtttcaactgctcagaaa
gaaggatataccgagcctgatcctaaaattgatttaagtggtatagacgtagctcgtaaa
atattaatcttagcaagggaaagcggctttgagttagaactctcagatattcaaaatgat
tcatttcttcctgaaaaaagcctaaatacaacaacaaatcatgatttttataatagctta
actgaatttgaacctcattttcaaaaaatctatcaagaagctagccatcaaaataagcgc
ttaaaatatgttgctgaatttataaacggaaaagcaaaagtaggcctccagcacattccg
ccaaagcatcctttttacaatttggaaggaagcgataatattgtacttttctacaccgaa
agataccctgtaaatccgctcattataaagggagctggagctggagcagacgttactgct
tctggtatttttgcagatgtaattagaattggtaataattaa
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