Thermosipho melanesiensis: Tmel_0708
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Entry
Tmel_0708 CDS
T00550
Name
(GenBank) uroporphyrin-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
tme
Thermosipho melanesiensis
Pathway
tme00860
Porphyrin metabolism
tme01100
Metabolic pathways
tme01110
Biosynthesis of secondary metabolites
tme01120
Microbial metabolism in diverse environments
tme01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
tme00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Tmel_0708
Enzymes [BR:
tme01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
Tmel_0708
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Tmel_0708
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Gene cluster
GFIT
Motif
Pfam:
TP_methylase
HEM4
Motif
Other DBs
NCBI-ProteinID:
ABR30572
UniProt:
A6LKX1
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Position
744906..746300
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AA seq
464 aa
AA seq
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MGIVYLVGAGPGDLKLVTVKGLEIIKNADTIVYDRLINKKLLSLAKKGAKLIYVGKKAGR
HYKTQEEINKILEEEAKNVEIVVRLKGGDPILFGRGAEEFEYLKSKNIEVKIIPGITSAI
AVPTYAGIPITHREVSSSVHIYTGHKEIDLRKNRGTSIFLMAGKNLNNLKKQLMKTYGKD
TPCAIISNGTYNTQKTIRTTISNLPKNIPSPSLLIIGSVVNKNINWFENQKLFGKKILIT
REYSSEFDLLEEQGAIVYCIPTFKIIPKYENIKDFMKKIDNYKSIVFTSKNGVIFFFETL
KMIKMDVRKIKADIAVVGEKTSKLLENYGIYPTLVGKTAKDIYDKITLPCATLTSNISTV
PTHIYKITAYENIPILKNKTKLQKIINDKVDYVVFTSPSSFHYFRNMVTLTSEIICAIGA
TTKSEIEKRGYKVHITPKKATFEELSKEIILWEGKHEKTKKIEK
NT seq
1395 nt
NT seq
+upstream
nt +downstream
nt
atgggaatagtttaccttgtaggtgctggaccaggtgacttaaagttagttactgtaaaa
ggtctagaaataattaaaaatgctgacacaatcgtctacgatagattgataaataaaaaa
ctactctctcttgcgaaaaaaggagcaaaacttatatacgttggaaaaaaggcaggaaga
cactataaaacacaagaagagataaacaaaatattagaagaagaggcaaagaatgttgaa
atagtcgtaagactaaaaggaggagatcccatactctttggtaggggagcagaagaattc
gaatatttaaaaagcaaaaacatagaagtaaaaataattccaggaattacatctgcaata
gctgtaccaacctatgcaggtatcccaataactcacagggaggtttcttcaagtgtccat
atatataccgggcacaaagaaatagacttaagaaaaaaccgtggaacatctatttttcta
atggcagggaaaaatcttaataatttaaaaaaacaattaatgaaaacatatggcaaagac
acgccatgtgcaattatttcaaatggtacgtataacacacaaaaaacaataagaaccaca
atttcaaatctaccaaaaaacattccatcaccttctctcttgataattggcagtgttgta
aataaaaacataaattggtttgaaaatcaaaaactatttggaaaaaagatactcataacc
agagaatatagtagtgaatttgacttattagaagaacaaggtgctattgtttactgtatt
cctacgtttaagataataccaaagtatgaaaatataaaggatttcatgaaaaaaatagat
aattacaaaagcattgttttcacaagcaaaaatggagtaattttcttttttgaaacgtta
aagatgataaaaatggatgtacgcaaaataaaagcagatatagcagtagtgggagaaaaa
acctcaaaattattggaaaattatggtatatatccaactttagttggaaaaacagcaaag
gatatatacgacaaaataactcttccctgtgcaacgttaacctcaaatatttcaactgtt
cctacacacatatataaaataactgcatacgaaaatataccaattttgaaaaacaaaact
aaacttcaaaaaataataaatgataaagtagattacgtggtatttaccagcccttcttca
ttccactatttcagaaacatggtcactttaacttctgaaattatttgtgctataggagcc
acaacaaaaagcgagatagaaaaacgcggatacaaagtacacataacacctaaaaaagca
acatttgaggaactttcaaaagaaataatactttgggagggaaaacatgaaaagactaag
aagattgagaaataa
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