Thermocaproicibacter melissae: NOG13_04335
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Entry
NOG13_04335 CDS
T09029
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tmel
Thermocaproicibacter melissae
Pathway
tmel00300
Lysine biosynthesis
tmel00550
Peptidoglycan biosynthesis
tmel01100
Metabolic pathways
tmel01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tmel00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NOG13_04335
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NOG13_04335
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NOG13_04335
Enzymes [BR:
tmel01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NOG13_04335
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
WBY64924
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Position
complement(866599..867963)
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AA seq
454 aa
AA seq
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MKMTAGEIATACGGQILTGSPETLVTSVTTDSRQVKQGTLFVPIVGEKIDAHQFIGKALE
AGASAVLTQEHQTAQGPGVWIAVDDTRAALQKIAAEWRKRFNGSVVGITGSVGKTTTKEM
TALALSAGMKVMKTEGNQNSQIGLPLTMFRLSPEYDAAVIEMGMSEFGEMSRLAAVASPD
YAVLTNIGLSHIGNLGSQENIRKEKLHITDRFHEKSVLFLNGDDPLLAELRGKLPFRTVY
FGTQPWCDFRAESVRIGAEASDFRYFTPDGRSGSIHLPVPGIHCVLDALAGLAVADQLGV
SLKKAAQALSTYQPLAMRMQIRRASKGYTVIDDSYNSSPDAAKSSLSVLAGFHSGKRVAV
LADMLELGDFSRQGHFSVGEYAANEDIEVLVTVGEEAKEIAEGALSVNPKMQCHVCKTNA
EALDVLSSVLEPGDTVLVKGSRGMKTDEIVKQLL
NT seq
1365 nt
NT seq
+upstream
nt +downstream
nt
atgaaaatgacagcgggggagattgcaaccgcatgcggcggacaaattctcacaggcagt
ccggaaactttggtgacttcggtaacgactgacagcaggcaagtgaagcagggaacgctt
tttgtgccgattgtcggggagaaaattgacgcgcatcagtttatcggcaaggcattggag
gcaggtgcgtcggctgtattgacgcaggagcaccagacagcgcaaggccccggtgtgtgg
atagcagttgatgacactcgggcggcgctgcagaaaatagcggccgagtggagaaaaagg
ttcaatgggtcagtcgtcgggataacaggcagcgtcggcaagacgacgacgaaagaaatg
acagctcttgcgctttcagcgggtatgaaagtcatgaaaaccgaaggcaaccagaacagt
cagattggccttccgctgacgatgttccgcctttcgccggaatatgatgcggcagtgatt
gagatgggcatgagtgagtttggcgaaatgagccgccttgctgccgttgcttctccggac
tatgcagtgttgaccaatattggtctttcacacatcggcaatctcggttcacaggagaat
atccgaaaagaaaagctccacattacagaccggtttcatgaaaaatcggttcttttccta
aacggcgatgacccgcttctcgctgagctgcgcgggaaactgccgttccgtaccgtgtat
ttcggaactcagccgtggtgcgatttccgagccgagtcggtccgtattggcgcggaagct
tccgatttccgttattttacacccgatgggcgaagcggaagcatacatcttcctgtaccg
ggaatacactgtgtgcttgatgcactcgcaggcctagcggtggcagatcagctgggcgtt
tcgctaaagaaagcggcacaggcactttcaacctatcagccgcttgccatgagaatgcag
attcgtcgtgcttccaagggctatacggtcatagatgactcctacaattcaagccccgac
gccgcaaaaagcagcctcagcgttttggcaggattccacagcggcaagcgtgtagccgtg
cttgcggatatgctggaactgggtgacttttcaaggcagggccatttcagtgtgggagaa
tatgcagcaaacgaagacatcgaggtgcttgttaccgtaggagaagaggcaaaagagata
gccgagggtgcactctcggtcaatccaaaaatgcaatgccatgtctgcaaaacaaatgca
gaggctttggatgttctttcttccgttttagaaccgggggataccgtccttgtgaagggc
tcccgcggaatgaagacggatgaaatcgtcaaacagcttctttga
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