Thiomicrospira microaerophila: JX580_04745
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Entry
JX580_04745 CDS
T08259
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
tmh
Thiomicrospira microaerophila
Pathway
tmh00230
Purine metabolism
tmh01100
Metabolic pathways
tmh01110
Biosynthesis of secondary metabolites
Module
tmh_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
tmh00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
JX580_04745 (purL)
Enzymes [BR:
tmh01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
JX580_04745 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
UQB43190
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Position
989897..993766
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AA seq
1289 aa
AA seq
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MHIIWGLPAHSDYRLNQLTQKLAQCGSVSSVRSQAVYFVESSEALSAETLSGLQQLLNGH
QDDLTPQQSASCVVTPRPGTISPWSSKATDIAKICGLKGIKRLEKGTAYFLKGVADEQLA
NFTPALYDRMTSVVWTDLSDIAALFEQHSPRELARVDILAGGREALVKANQGLGLALSDD
EIDYLVENFKQLKRNPTDAELMMFAQANSEHCRHKIFNADWVIDGETKDKSLFGMIRNTY
QNNPDGVLSAYSDNAAVLAGPDATRFFPDPKTAEYGYYNEPTHVQIKVETHNHPTAISPF
PGAATGAGGEIRDEGATGQGSKPKSGLTGFTVSNLNIPGFKQPWERDYGRPGRIVSPLDI
MIEGPLGAAGYNNEFGRPAINGYFRTYENPLLTHEGEEVRGYHKPIMLAGGLGNIRDMHV
KKQAIPVGAKLVVLGGPAMLIGLGGGAASSVDTGAGSEALDFASVQRDNPEMERRAQEVI
DRCTYLGKDTPIASIHDVGAGGLSNAFPELVNDAGRGGKFDLRKVPNDEPGMSPMEIWCN
ESQERYVIAIYPDKIEQFEAICKRERAIYAIVGEATAEQELVVNDTVFQANPVDLPLNVL
LGKPPKMQRDVVSRPLPQPGFETAVLELEEVTERLLKLPTIASKSFLITIGDRSITGMVT
RDQMVGPWQVPVADVGVTASDYQGYSGEAMAMGERPPVALVNPKASARLAIAEAITNIAA
AKIGQISDIKMSANWMAAAGHPGEDSALFDAVETVGMELCPALGISVPVGKDSMSMKTVW
QEGDQAKAVISPVSLNITAFAVVEDVRKTLTPQIRTDQGETQLALIDLGRKQNRVGASCL
AQVYNQVGEAPADLDDAQDLINFFNAIQRLNQAGLLLAYHDRADGGLLVTLMEMAFAGHC
GVDIDVTELGVEPIAALTAEELGVVIQVKTEDLLQVNQILADAGLADLVHWVGAPNSSDE
IVIKAQEKTLLKGARAHYQAWWSETSYRIQAMRDNEVCAEQEFEAIKDSAHTELVAKPSF
DINDNIAAPYIQSGVRPKVAILREQGVNGQQEMAAAFDRAGFSAVDVHMSDILEGRVTLQ
DFKGLVACGGFSYGDVLGAGRGWANSILFNAMARDQFEAYFNRDDTFSLGVCNGCQMMSN
LKSIIPGADHWPAFVRNRSEQFEARLSLVEVQESPSVLLAGMAGSRMPVAVAHGEGRVDF
GSASAEAAKGLIGLRYVNAQGVPTERYPFNPNGSEQGITGLTTEDGRVTIMMPHPERVFR
AVQHSWCPDDWTEDAPWLRLFRNARKWVG
NT seq
3870 nt
NT seq
+upstream
nt +downstream
nt
atgcacatcatttgggggcttccggctcattctgattatcgtttaaatcaattgacacaa
aaacttgcacaatgtggttctgtgtcatctgtacgttcacaagcggtttattttgttgaa
tcaagcgaagccttgagcgccgaaaccctaagtggtttgcagcaacttctcaatggacat
caagacgacttgacaccgcagcagtctgcaagctgtgtggttacgccgcgtccgggtacg
atttcgccctggtcatctaaagcgaccgatattgccaagatttgtggtttgaaaggtatt
aagcgtcttgaaaagggcacggcttattttctaaagggcgtggcggacgagcagctcgcc
aactttacgccagcactttatgatcgcatgacctcagtggtctggaccgacttgtctgac
attgctgcgctgtttgaacaacatagtccgcgtgaattggcgcgtgttgatattttagct
ggtggtcgtgaggctttggtcaaagcgaaccagggtttaggcttggcgttaagtgatgac
gaaattgattatttggttgaaaacttcaagcagcttaaacggaatccgaccgatgccgaa
ttgatgatgtttgcgcaagccaactcggaacattgtcgtcacaaaatttttaatgccgat
tgggtgattgatggtgaaaccaaggataaatcactgtttgggatgatccgcaacacctat
caaaacaatccagacggtgtattgtcggcctatagcgacaatgccgcggtgttggccggg
ccggatgcgacgcgctttttcccagacccgaaaaccgctgaatacggctattacaatgaa
ccgacccatgtgcaaattaaggttgaaacccataaccatccgaccgcgatttcgcctttc
ccgggggctgcgaccggtgcgggcggtgaaattcgtgacgaaggtgcgaccggacagggt
tctaagcccaagtcggggttaaccggttttaccgtatctaacttgaatattccagggttt
aaacagccttgggagcgtgattatgggcgtccgggtcgtattgtgtcaccgttggatatt
atgattgaagggccactgggtgcagcgggttataacaatgaatttggccgtccggcgatt
aatggctatttccgtacttatgaaaacccattgttgactcacgaaggcgaagaagtgcgc
ggttaccacaagcccattatgttggccggtggcttgggcaatattcgtgatatgcacgtt
aaaaaacaagctattccggtcggtgcaaagcttgtcgtgctgggcggcccggcgatgttg
attggcttgggtggcggtgccgcgtcgagtgtcgataccggtgccggttcggaagccttg
gattttgcctcggtgcagcgtgataatccggaaatggagcgtcgtgcgcaggaggtgatt
gaccgttgtacctatcttggcaaggatacaccgattgcgtcaattcatgatgtgggtgcc
ggtggcttgtcgaatgcctttccggaactggttaacgatgccgggcgcggcggtaaattt
gatttgcgtaaagtgccaaatgacgagccgggcatgtcaccgatggaaatctggtgtaac
gaatcgcaagagcgctatgtgatcgcgatctatcccgacaagattgaacaatttgaagcc
atttgtaaacgtgaacgcgctatttacgcgattgttggcgaggccaccgctgagcaagag
ttggtggtgaatgatacggttttccaagcaaatccggttgatttgccattgaatgtgtta
ctcggcaaaccgccaaaaatgcagcgtgatgtggtgagtcgtcctttgccgcaaccgggt
tttgaaactgcagtgcttgagctggaagaagtcaccgagcgtttgttaaagctgccgacc
attgccagtaagtcatttttaatcacgattggtgaccgcagtattaccggtatggtcacg
cgtgatcaaatggttgggccttggcaagtaccggtggcggatgtcggggttactgcatcg
gattaccaaggttatagcggtgaagccatggcgatgggggagcgcccgccagtggcgctc
gttaatccgaaagcgtctgcacgtttggcgattgccgaggcgattaccaatattgccgcc
gctaaaattggtcagatttcagatattaaaatgtcagctaactggatggccgccgccggt
catccgggtgaagactcggctttatttgatgcggttgaaaccgtgggaatggaactgtgt
ccggctttgggtatttcggtgccggtcggcaaagattccatgtcgatgaaaaccgtttgg
caagagggtgatcaggctaaagccgtgatttcaccggtatcgctaaacattaccgccttt
gcggtggtggaagacgtgcgcaaaaccttaacgccgcaaattcgcactgatcagggtgaa
acccaattagcattgattgatttggggcgcaagcaaaaccgcgttggcgcgagctgttta
gcgcaggtttataatcaagtgggcgaagccccggctgatttggacgatgcgcaagacttg
attaatttctttaacgccatccagcgccttaatcaagcaggcctgttgttggcctatcat
gaccgcgcagacggtggcttattggtcaccttgatggaaatggcgtttgccggtcattgc
ggtgtggatattgacgtcactgaactcggtgttgagccgattgcggccttaacggcagaa
gagttgggcgtggtcattcaggttaaaacggaagatttgttgcaggttaaccaaattttg
gctgatgcaggcctggcggacttggtgcattgggtgggggcgccaaatagttcggatgaa
attgtgattaaagcacaagaaaagacgctattaaaaggtgcgcgtgcgcattaccaggcc
tggtggtcggaaacctcttatcgtattcaagcgatgcgtgataatgaagtttgtgccgag
caggagtttgaggcgattaaagattcggcgcacactgaattggtggcgaagcccagcttt
gacattaatgacaatattgccgcgccttatattcagagcggcgtgcgcccaaaagtggcc
attttgcgtgagcagggcgttaacggccagcaggaaatggcggcggcgtttgatcgtgcc
ggcttcagtgcggtcgatgttcacatgagtgatattctggaaggacgcgttacgctacag
gattttaaaggcttggtcgcttgtggtggtttttcttatggtgacgtattgggtgccggg
cgtggttgggcaaactctatcctgtttaacgcgatggcgcgagatcaatttgaagcctat
tttaaccgtgatgataccttcagtttaggggtgtgtaacggttgtcagatgatgtcgaat
ctcaagtcgattattcctggtgcagaccattggccggcgtttgtacgcaatcgttcagag
caatttgaagcgcgtttatccttggttgaagtgcaggaatcgccatctgtattactggcc
ggtatggcgggcagccgtatgccggtggcggttgcgcatggcgaagggcgggttgatttt
ggtagtgcgtctgcagaggccgccaaaggcttgattggcttgcgttatgtcaatgcacaa
ggcgtaccgaccgagcgttatccgtttaacccgaacggctcagagcagggcatcaccggc
ttgaccaccgaggacgggcgggtcaccattatgatgccgcatcctgagcgggtattccgt
gcagtacagcactcgtggtgtccggatgactggacggaagatgcgccttggttacgctta
ttccgtaatgcgcgcaagtgggtgggctag
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