KEGG   Thermotoga maritima MSB8: THEMA_03430
Entry
THEMA_03430       CDS       T02976                                 
Name
(GenBank) D-alanyl-alanine synthetase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
tmi  Thermotoga maritima MSB8
Pathway
tmi00470  D-Amino acid metabolism
tmi00550  Peptidoglycan biosynthesis
tmi01100  Metabolic pathways
tmi01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:tmi00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    THEMA_03430
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    THEMA_03430
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    THEMA_03430
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:tmi01011]
    THEMA_03430
Enzymes [BR:tmi01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     THEMA_03430
Peptidoglycan biosynthesis and degradation proteins [BR:tmi01011]
 Precursor biosynthesis
  Amino acid ligase
   THEMA_03430
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N ATP-grasp_3 ATP-grasp_4 ATP-grasp CPSase_L_D2 RimK GARS_A
Other DBs
NCBI-ProteinID: AHD17977
UniProt: P46805
LinkDB
Position
complement(675960..676871)
AA seq 303 aa
MRVALLMGGVSREREISLRSGERVKKALEKLGYEHTVFDVREDFLKKVDQLKSFDVVFNV
LHGTFGEDGTLQAILDFLGIRYTGSDAFSSMICFDKLVTYRFLKGTVEIPDFVEIKEFMK
TSPLGYPCVVKPRREGSSIGVFVCESDEEFQHALKEDLPRYGSVIVQKYIPGREMTVSIL
ETEKGFEILPVLELRPKRRFYDYVAKYTKGETEFILPAPLNPSEERLVKEMALKAFVEAG
CRGFGRVDGIFSDGRFYFLEINTVPGLTETSDLPASAKAGGIEFEELVEIILKSAFLKEG
VRV
NT seq 912 nt   +upstreamnt  +downstreamnt
gtgagagtggctctcctgatgggaggagtgtcgagggaaagggaaatctctctgagaagc
ggagaaagggtaaaaaaggctcttgaaaaactcgggtatgaacacaccgtttttgacgtt
agagaagattttctcaagaaagtggatcagttgaaaagttttgatgtggtcttcaacgtt
ctccatggaactttcggtgaggatggaacgcttcaggcaattctggattttttggggatc
agatacaccgggtccgatgcgttttcaagcatgatatgttttgataaactcgtgacttac
aggtttttaaagggcaccgtcgagatacctgattttgtggagatcaaggaattcatgaaa
acttctccccttgggtatccctgtgtggtaaaaccgaggagagagggttcaagcatagga
gtgttcgtttgtgaatcggatgaagagtttcaacacgcgctcaaggaagatttaccacga
tatgggagtgtgattgttcaaaagtacatccccggcagggaaatgactgtgtctatttta
gaaacggaaaagggcttcgaaattcttcccgttcttgagttgcgaccaaagcgtcgtttc
tacgattacgttgcgaagtacacgaaaggtgaaacggagttcattcttcctgctcctttg
aatccttcagaagaacgccttgtcaaggaaatggctctcaaagcgtttgtagaagctggt
tgcagaggttttgggagggtggatggtattttcagcgatggcaggttctactttctggaa
atcaacacggtaccgggtctaacggaaaccagtgatctcccagcgagcgcgaaagcggga
ggaatcgagttcgaggaactcgttgagatcatcttaaagagcgcttttttgaaagaaggg
gtgagagtatga

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