KEGG   Thermotoga maritima MSB8: THEMA_08090
Entry
THEMA_08090       CDS       T02976                                 
Name
(GenBank) IMP cyclohydrolase
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
tmi  Thermotoga maritima MSB8
Pathway
tmi00230  Purine metabolism
tmi00670  One carbon pool by folate
tmi01100  Metabolic pathways
tmi01110  Biosynthesis of secondary metabolites
Module
tmi_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:tmi00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    THEMA_08090
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    THEMA_08090
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:tmi04147]
    THEMA_08090
Enzymes [BR:tmi01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     THEMA_08090
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     THEMA_08090
Exosome [BR:tmi04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   THEMA_08090
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS CoA_binding_2
Other DBs
NCBI-ProteinID: AHD18846
UniProt: Q9X0X6
Structure
LinkDB
Position
complement(1539733..1541091)
AA seq 452 aa
MKRILVSLYEKEKYLDILRELHEKGWEIWASSGTAKFLKSNGIEANDVSTITGFENLLGG
LVKTLHPEIFAGILGPEPRWDVVFVDLYPPPDIDIGGVALLRAAAKNWKKVKPAFDMETL
KLAIEIDDEETRKYLAGMTFAFTSVYDSIRANQFVEGISLAFKREDLQLRYGENPHEKAF
VYGKPAFEILHEGKTISFNNILDAENAWFMAKNLPRMGAVVVKHQSPCGAAIGEDKVEIV
KKAIEADDESSFGGILAVNFEMDEEVAKSLKKYLEVIVAPSFTQEAIEVLSKKKVRLLKP
GDYASWAGKMAFGSLVLSERKYPEGNFELVVGEPLSEKELEDLEFAYRVVEGAKSNAVLI
AKDGVTVGIGSGQPSRKRAAWIATVMAGEKAKGAVAASDAFFPFPDSLEILAQAGVKAVV
APLGSIRDEEVIEKARELGITFYKAPSRVFRH
NT seq 1359 nt   +upstreamnt  +downstreamnt
ttgaagaggatattggttagtctctacgagaaagaaaaatatctggatattctgagagaa
ctccacgaaaaaggctgggagatctgggcgagctccggcaccgccaagtttttgaaatca
aacggaatagaagcaaacgacgtgagcaccataacgggtttcgagaatctcctcggaggg
ctcgtgaagaccctccacccggagatattcgccggcatcctcggaccggaacccagatgg
gatgtggtctttgtggacctatatccacccccagacatcgacataggaggagtcgctctt
cttcgagcagctgccaaaaactggaaaaaggtgaaacccgctttcgacatggaaacactc
aaactcgcgattgagatagacgacgaagagacgagaaagtacctcgctggaatgaccttt
gcgttcaccagtgtgtacgattcgataagggccaaccagtttgtcgagggtatttctctc
gccttcaagagggaagatcttcagctgaggtacggagagaaccctcacgaaaaagcgttt
gtgtatggaaaaccagcttttgagattctgcacgaaggaaagacaatctcattcaacaac
atcttagacgcggaaaacgcgtggttcatggcgaagaacctgccgaggatgggtgcggtt
gtggtgaaacaccaatctccctgtggtgctgcgataggagaagacaaagtggaaatcgtg
aagaaggccatcgaggcggacgacgaatccagttttggagggatcctggccgtgaacttc
gaaatggacgaagaagttgcgaagtcattgaaaaagtacctcgaggtgatcgtggcacct
tccttcacacaggaagcgatcgaggttctctctaagaaaaaagtgcgtctcttgaagcct
ggggattacgcttcgtgggctggaaagatggcattcggttctctcgtcctgagtgaaaga
aagtaccccgaagggaattttgaactggtagttggagagcctctctcggaaaaagagctt
gaggatctggaattcgcttaccgtgttgtggaaggagcgaaatccaacgctgttctcata
gcaaaagacggtgtaactgtgggaatagggagcgggcagccttcgagaaagagagctgcc
tggatcgccaccgtgatggcaggagaaaaagcgaagggagcggttgcggcttccgatgcg
ttcttcccgttcccggactcgctcgaaatactcgctcaggctggtgtgaaagcggtggtc
gctcctctcggatccataagagacgaagaagtgatcgaaaaagccagagaacttggaatc
acgttctacaaagctccgagcagggttttcaggcactga

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