Thermotoga maritima MSB8: THEMA_08105
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Entry
THEMA_08105 CDS
T02976
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
tmi
Thermotoga maritima MSB8
Pathway
tmi00230
Purine metabolism
tmi01100
Metabolic pathways
tmi01110
Biosynthesis of secondary metabolites
Module
tmi_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
tmi00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
THEMA_08105
Enzymes [BR:
tmi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
THEMA_08105
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Gene cluster
GFIT
Motif
Pfam:
PurL_C
AIRS
AIRS_C
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AHD18849
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Position
complement(1542950..1544755)
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AA seq
601 aa
AA seq
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MRYLNILKEKLGREPTFVELQAFSVMWSEHCGYSHTKKYIRRLPKTGFEGNAGVVNLDDY
YSVAFKIESHNHPSAIEPYNGAATGVGGIIRDVLAMGARPTAIFDSLHMSRIIDGIIEGI
ADYGNSIGVPTVGGELRISSLYAHNPLVNVLAAGVVRNDMLVDSKASRPGQVIVIFGGAT
GRDGIHGASFASEDLTGDKATKLSIQVGDPFAEKMLIEAFLEMVEEGLVEGAQDLGAGGV
LSATSELVAKGNLGAIVHLDRVPLREPDMEPWEILISESQERMAVVTSPQKASRILEIAR
KHLLFGDVVAEVIEEPVYRVMYRNDLVMEVPVQLLANAPEEDIVEYTPGKIPEFKRVEFE
EVNAREVFEQYDHMVGTDTVVPPGFGAAVMRIKRDGGYSLVTHSRADLALQDTYWGTLIA
VLESVRKTLSVGAEPLAITNCVNYGDPDVDPVGLSAMMTALKNACEFSGVPVASGNASLY
NTYQGKPIPPTLVVGMLGKVNPQKVAKPKPSKVFAVGWNDFELEREKELWRAIRKLSEEG
AFILSSSQLLTRTHVETFREYGLKIEVKLPEVRPAHQMVLVFSERTPVVDVPVKEIGTLS
R
NT seq
1806 nt
NT seq
+upstream
nt +downstream
nt
ttgagatatctgaacattctcaaggagaagcttggaagagaacccaccttcgtcgagctt
caggctttttcagtcatgtggagcgaacactgtggatactcccacacgaagaaatacata
agaagattaccgaaaacgggttttgagggaaacgcgggtgtggtgaacctggatgattac
tattccgttgctttcaagatagagagccacaatcacccgagtgcgatagaaccttacaac
ggtgcagcaacgggtgtcggtggaatcatcagagacgtcctcgcgatgggagcccgccca
acggccatattcgattcactccacatgtcccgaatcatagacggtatcatagagggaata
gccgattacggtaattccataggcgttccaacggtcggtggagaactcaggatctcctca
ctatacgcgcacaaccccctcgtgaacgtgctcgcagcgggtgttgtgagaaacgacatg
ctggtcgattcgaaagcatcgagaccgggacaggtcatagtgatcttcggaggagccaca
ggaagggacggaatccacggggcgtctttcgcttcggaggatctcacgggtgataaggca
accaagctttcaattcaggttggtgacccgttcgctgaaaagatgctcatagaagcgttc
ctggagatggtggaagagggactcgtggaaggagctcaggatctgggagcgggcggtgtg
ctgtccgcaacttcggaactcgtagcgaaggggaatctcggagcgatcgttcatctggac
cgtgttcccctgagagaaccggatatggagccctgggaaatcctcataagcgaaagccaa
gaaagaatggcggtcgtcacatcacctcagaaggcgagccgcattctggaaatagccagg
aagcaccttcttttcggcgatgtcgttgccgaagtgatagaagaaccagtttacagggtg
atgtacagaaacgatctcgtcatggaagttcccgtccagctcctcgcaaacgccccagaa
gaggacatagtcgaatacacacccggaaagatcccagagttcaaaagggtggaattcgaa
gaggtgaacgcgagggaagtcttcgagcagtacgatcacatggtcggaacggataccgtg
gttccacccggattcggcgcggccgtgatgagaataaagagagacggggggtactccctc
gtcacacacagcagggcggatctggctcttcaggatacctactggggaaccctcatagcc
gtgctcgagagtgtgagaaagacgctcagcgttggtgcggaacccctcgctataacgaac
tgcgtgaactacggggatcccgatgttgatccggtgggactttcggccatgatgaccgct
ctcaagaacgcttgcgaattctccggtgttcccgttgcatcgggaaacgcttctctctac
aacacgtaccagggaaaacccattccacccaccctggttgtgggaatgttggggaaggtg
aacccgcagaaagtggcaaaaccgaagccttcgaaggtgttcgcggtgggatggaacgac
ttcgaactcgaaagggaaaaagaactctggagagccataagaaaactctcagaagaaggt
gctttcatcctctcttcgtcacagcttctgacgagaactcacgtggagactttcagagag
tacggcttgaagatcgaagtgaaactgccagaagtgaggccggcgcatcagatggtgctc
gtcttctctgagagaactcccgtagtcgatgttcctgtgaaggagatcggaacgctctcg
aggtga
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