Temperatibacter marinus: QGN29_08460
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Entry
QGN29_08460 CDS
T09370
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tmk
Temperatibacter marinus
Pathway
tmk00300
Lysine biosynthesis
tmk00550
Peptidoglycan biosynthesis
tmk01100
Metabolic pathways
tmk01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tmk00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
QGN29_08460 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
QGN29_08460 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
QGN29_08460 (murF)
Enzymes [BR:
tmk01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
QGN29_08460 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
AAA_16
Motif
Other DBs
NCBI-ProteinID:
WND01590
UniProt:
A0AA52EBB6
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Position
1900914..1902341
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AA seq
475 aa
AA seq
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MFDPVWTALEISQSLGMPVQDFKACTGVQIDSRSIVPGDLFVALSGCETDGHNFVSNAFE
SGAHAAIVSRLPSDLEQSDERLIFVEDTGVALNRLAHAARARASARCIAVTGSAGKTSVV
QALRAALARAGEAHSSIKSFNNHVGVPVSLARMHAQSEYGVFEVGMSAQGEIEPLAQLIK
PDVCIITTIGAAHLKAFEDREAIAREKASIFKGMSAGGTAIIGMQHAYSDLLCTLAKAHD
LKVIKVGFDDQCDVRPVKVYEQATCSCLSIGLADRLITFKVNQPGPEWILNAMMILTAVN
AVKGDIAEAALSLASLVPEKGRGRLHELMFENGTVTLQDDSYNANPLSMRAALGRFARLT
KETTQKSIAVLGDMAELGRNEEAEHLALVPYLKQTGFDLALTVGDYMPKASKEAGIETIS
CKNVAEISDVLQTKLSGNELIYVKGSNSTHLTRVVDDLIKLSRYEGHTTALGQGA
NT seq
1428 nt
NT seq
+upstream
nt +downstream
nt
atgtttgatcctgtttggacagctttggaaatatcacagtctctcggtatgcccgtgcag
gattttaaggcctgtactggggttcagattgatagccgatctatagtgccgggtgattta
tttgttgccctgtcagggtgtgaaacagatggacataattttgtttcaaatgcttttgaa
agtggcgcacatgcagccattgtgagtaggcttccaagtgatcttgaacaatcagacgag
cgtttaatctttgttgaagatacgggcgttgctttgaatagactggctcacgcagctcgc
gctcgagcgtcggctcgctgtattgctgtaacaggaagtgcaggaaaaacaagtgttgtg
caagctctgagagcagctctagcaagagctggagaggcgcattcaagtatcaaaagcttt
aataatcatgtgggtgtgcccgtgtcgcttgcccgtatgcatgctcagtcagagtacggg
gtttttgaagtcggtatgtcagcacaaggtgagattgaaccgctagctcagttaattaag
cccgatgtctgtattattaccacaattggtgcagcccatttaaaagcctttgaggatcgt
gaggcgattgcgcgtgagaaggcttctatttttaaagggatgtcagcaggcgggaccgca
atcataggtatgcagcatgcctacagcgaccttttatgcacgcttgcaaaagcgcatgat
ctgaaagttattaaggttgggtttgatgatcaatgcgatgtaaggcccgttaaagtatat
gagcaggcaacctgttcgtgcctctccataggtcttgcagatagactcattacctttaag
gttaatcaaccggggccagagtggatccttaatgcgatgatgatactcacagcagttaat
gctgtaaaaggggatattgctgaggctgcactttcgctggcttctcttgtacctgaaaag
ggcaggggtcgattgcatgaactgatgtttgaaaacggcacagtgaccctgcaagacgat
agctataatgctaaccctttatcaatgagggctgcacttggcaggtttgcccgtctcaca
aaggaaacgacgcaaaaatccatcgctgttcttggggatatggctgaacttggtcggaat
gaagaagcagaacatttggcccttgtcccctatttaaagcagacagggtttgatctggcg
ttaaccgttggggattatatgccaaaagcttcaaaagaggcaggaatagagacaattagc
tgtaaaaatgttgcagaaatatctgatgttttacaaaccaaattaagcgggaatgagcta
atttacgttaagggctcaaattcaacacatttaacaagagtagttgatgaccttattaaa
ctttctcgctatgaagggcacacaacagcgcttgggcaaggcgcttaa
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