Tistrella mobilis: TMO_b0190
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Entry
TMO_b0190 CDS
T02128
Name
(GenBank) 2-oxoisovalerate dehydrogenase (alpha subunit)
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
tmo
Tistrella mobilis
Pathway
tmo00280
Valine, leucine and isoleucine degradation
tmo00640
Propanoate metabolism
tmo00785
Lipoic acid metabolism
tmo01100
Metabolic pathways
tmo01110
Biosynthesis of secondary metabolites
tmo01210
2-Oxocarboxylic acid metabolism
Module
tmo_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tmo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
TMO_b0190
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
TMO_b0190
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
TMO_b0190
Enzymes [BR:
tmo01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
TMO_b0190
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Motif
Pfam:
E1_dh
OxoDH_E1alpha_N
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
AFK56198
UniProt:
I3TTW0
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Position
pTM2:207731..208963
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AA seq
410 aa
AA seq
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MSTSEHLSLHVPEPAVRPGDTPDFSTVKIPKAGAVPRPEVDADPEQMRDLAFSIIRVLNR
NGEAVGPWAGALTDDELLDGLRHMMTLRAFDARMLIAQRQGKTSFYMQHLGEEAVSCAFR
KALVDGDMNFPTYRQAGLLIAGGYSMVDMMCQIYSNARDPLKGRQLPVMYSSREHGFFTI
SGNLATQFVQAVGWAMASAIRNDTKIAAAWIGDGSTAESDFHAALVFASTYKAPVVLNVV
NNQWAISTFQGIARGGSGTFAARGLGFGIPSLRVDGNDYLAVHAVAKWAAERARRNLGPT
LIEYVTYRVGAHSTSDDPSAYRPKAESTAWPLGDPVIRLKNHLITRGVWSEDRHKQTEAE
ILDTVIAAQKEAESHGTLHAGAKPSARDMFDGVFAEMPAHLRRQRQQAGV
NT seq
1233 nt
NT seq
+upstream
nt +downstream
nt
atgtccacatccgaacaccttagtctgcatgtacccgagccggcggtccggccgggcgac
acccccgacttctcgaccgtcaagattcccaaagccggggccgtgcccagacccgaggtc
gatgccgatccggagcagatgcgcgacctcgccttctcgatcatccgcgtgctgaaccgc
aatggcgaagccgtcggcccctgggccggcgcgcttaccgatgacgagctgctcgacggg
ctgcgccacatgatgacgctgcgcgccttcgatgcgcgcatgctcatcgcccagcgccag
ggcaagacctcgttctatatgcagcatctgggcgaggaggcggtcagctgcgccttccgc
aaggcgctggtcgacggcgacatgaacttccctacctatcgtcaagcggggctgctgatc
gccggcggctattcgatggtcgacatgatgtgtcagatctattcgaatgcccgcgacccg
ctgaagggccggcagctgccggtgatgtattcctcgcgcgagcacggtttcttcaccatc
tcgggcaacctcgccacccagttcgtgcaggcggtgggctgggcgatggcctcggccatc
cgcaacgacaccaagatcgccgcggcctggatcggcgacggctccaccgccgagagcgat
ttccacgccgccctggtcttcgcctccacctacaaggcgccggtggtgctgaacgtggtc
aacaatcagtgggccatttctaccttccagggcatcgcccgcggcggatcgggcactttc
gccgcgcgcggtctgggcttcggcatcccgtcgctgcgtgtcgacggcaacgactatctg
gcggtccacgccgtcgccaaatgggcggcggagcgggcgcggcgcaatctgggcccgacg
ctgatcgaatacgtcacctatcgtgtcggcgcgcattccacgtccgacgacccttcggcc
tatcgtcccaaggctgaaagcaccgcctggccgctgggcgatccggtgatccggctcaag
aaccatctgatcacccgcggcgtctggtcggaagaccgccacaagcagaccgaggccgaa
atcctggacacggtgatcgccgcccagaaggaagccgaaagccacggcacgctgcacgcg
ggcgccaagccttcggcccgcgacatgttcgacggcgtcttcgccgagatgccggcccat
ctgcgccggcagcgccagcaggcgggagtctga
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