Thermaerobacter marianensis: Tmar_1430
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Entry
Tmar_1430 CDS
T01388
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
tmr
Thermaerobacter marianensis
Pathway
tmr00290
Valine, leucine and isoleucine biosynthesis
tmr00620
Pyruvate metabolism
tmr01100
Metabolic pathways
tmr01110
Biosynthesis of secondary metabolites
tmr01210
2-Oxocarboxylic acid metabolism
tmr01230
Biosynthesis of amino acids
Module
tmr_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
tmr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Tmar_1430
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Tmar_1430
Enzymes [BR:
tmr01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Tmar_1430
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
ADU51543
UniProt:
E6SMQ1
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All DBs
Position
1713789..1715678
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AA seq
629 aa
AA seq
DB search
MGDGTAVRPPHRPDGGPAGDAQRLDGQARRAAAGAPGGPTGPAGRPAGEAGAGSTPLDVV
LYDTTLRDGTQRAGIHLTLADKVRLARRLDAFGIPYVEGGWPGSNPKDAAFFRVLQDQPL
ERARLVAFTSTRRPGHAAHHDPVLAAALAAATPAVCVVGKAWDRHVTVALGTTLAENLAM
VRETVAFLKEHGREVIFDAEHFFDGFAANPDYALAVLAAAEEAGADWLVLCDTNGGTLPG
AIAQAVRAAAACTRVPLGIHCHDDAGLGVANSLAAVEAGCRMVQGTVNGYGERCGNANLL
TIAANLELKMGRRCLPPGALAGLTALSRFTSEVANLPHREEAPYVGANAFAHKAGIHVSA
LLKEPALYEHVDPARVGNGRRVLVSELSGRANLRYVLGSDLDEPALARLLARVKELEHQG
YQFEGAEGTLALLAWEARRAADSSGPAASGSTLPRSAGDPPEAPFVLESYRVTAAHEPGA
GSRVEATIKVRVGGRVVHTAAEGNGPVNALDAALRKALSEVYPDVQQVRLVDYKVRVLEG
DAGTGARVRVLVECTDGRRRWGTVGVSTNILEASWHALADGLRYYLLGLHASGLNAAAAA
AGASGEARPDADAAGGPGPARTAASRVVG
NT seq
1890 nt
NT seq
+upstream
nt +downstream
nt
atgggcgacggaaccgctgtccgtcccccgcaccgccccgatggtggacccgctggcgac
gcccaacggctcgatggccaagcccgccgcgccgccgccggcgcccctggcgggccgacc
ggccccgccggccgacccgccggcgaggccggagcaggctcgaccccgctggacgtggtg
ctctacgacaccaccctgcgcgacggcacccagcgcgccgggatccacctgaccctggcc
gacaaggtgcgcctggcgcgccggctcgacgccttcggcatcccctacgtggagggcggc
tggcccgggtcgaacccgaaggatgccgcgttcttccgggtcctgcaggaccagcccctg
gagcgggcccggctcgtcgccttcaccagcacccgccgccccggccacgcggcccaccac
gacccggtcctggccgcggcgctggccgccgccacccccgccgtgtgcgtggtcggcaag
gcgtgggaccggcacgtcaccgtcgccctgggcaccaccctggcggaaaacctggccatg
gtgcgggagacggtggcctttctcaaggagcacggccgggaggtgatcttcgacgccgag
cacttcttcgacgggttcgccgccaacccggactacgccctggccgtgctggcggcggcg
gaggaggccggcgccgactggctcgtcctctgcgacaccaacggggggaccctgccgggc
gccattgcccaggcggtgcgggccgcagccgcgtgcacccgggtccccctgggcatccac
tgccacgacgacgcgggcctcggcgtcgccaactccctggctgccgtggaagccggctgc
cggatggtccagggcacggtgaacggctacggcgagcggtgcggcaacgccaacctgctg
accatcgccgccaacctggagctcaagatgggccgccgctgcctgccgcccggcgccctg
gccggcctcaccgccctgagccgcttcaccagcgaggtggccaacctgccccaccgggag
gaagccccttacgtgggcgccaacgccttcgcccacaaggccggcatccacgtctccgcc
ctgctcaaggaacccgccctctacgagcacgtggaccccgcacgggtgggcaacgggcgc
cgggtgctggtctccgagctcagcggccgtgccaacctccgctacgtgctgggttccgat
ctggacgaaccggccctggcccggctcctggcgcgggtcaaggagctggagcaccagggg
taccagttcgaaggggccgagggcaccctggccctgctggcctgggaagcgaggcgggcc
gcggactcttccggccccgccgcttccggctccacccttccccgctcggcgggggatccg
ccggaggcccccttcgtcctggaatcctaccgggtcaccgccgcccacgagcccggcgcc
ggttcccgggtcgaggccaccatcaaggtgcgggtcggcggccgggtcgtccacaccgcg
gccgagggcaacgggcccgtcaacgccctggacgccgccctgcggaaggcgctgtcggag
gtctacccggacgtccagcaggtccggctggtggactacaaggtgcgggtcctggagggc
gacgccggcaccggcgcccgcgtgcgggtgctggtggagtgcaccgacggccggcggcgg
tggggcaccgtgggcgtgtccaccaacatcttggaggcgtcgtggcacgccctggccgac
ggcctccgctattatctcttggggttgcatgcgtcggggttgaacgcggccgccgcagcg
gccggcgcctccggcgaagctcggcccgatgcggacgccgccggcgggcccggcccggcc
cgcactgccgcgtcccgggtggtcgggtag
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