Thermaerobacter marianensis: Tmar_1776
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Entry
Tmar_1776 CDS
T01388
Name
(GenBank) 3-isopropylmalate dehydrogenase
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
tmr
Thermaerobacter marianensis
Pathway
tmr00290
Valine, leucine and isoleucine biosynthesis
tmr00660
C5-Branched dibasic acid metabolism
tmr01100
Metabolic pathways
tmr01110
Biosynthesis of secondary metabolites
tmr01210
2-Oxocarboxylic acid metabolism
tmr01230
Biosynthesis of amino acids
Module
tmr_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
tmr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
Tmar_1776
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Tmar_1776
Enzymes [BR:
tmr01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
Tmar_1776
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Gene cluster
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Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-ProteinID:
ADU51878
UniProt:
E6SHZ8
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Position
2125597..2127099
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AA seq
500 aa
AA seq
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MTYRIAVLPGDGIGPEVTREAVRVLEAVGAAAGIRFEFAEAPVGGAAVDATGDPFPPETE
QLCMAADAILLGAVGGPRWDREPVPRRPESGLLRLRKAVGAYANLRPVRVHPALAGRGPL
RPEVVGGGVDILIVRELTGGLYYGERGVQQEPFGERAYDTMVYTTPEIERIVRMAFQLAR
GRRRRVISVDKSNVLETSRLWRRVTEAVAEDFPDVELEHMLVDNAAMQLVRNPQRFDVLV
TENTFGDILSDLGAALAGSLGLLPSASLGLPGRPPLFEPVHGSAPDIAGRGIANPLGAIA
SAAMMLRHAFGLQREAQAVEEAIDDLLAAGPWTPDIAPPGAPVASTEDVGRAIARRVRER
LAPGPLEPLGPVAGRDGRGTQDGRGSQDGSGLAGDPVAAVWIAGEYGFRPLPPDEPAPPA
AAPAATGTVRAGDPATGASRDAMTPDALANGPTAAGGTAADTATGTNGTATRSESPVRTP
ARRGTGAGTTRRRARARKGA
NT seq
1503 nt
NT seq
+upstream
nt +downstream
nt
atgacgtaccgcatcgccgtcctgcccggggacggcatcggccccgaggtgacgcgggaa
gccgtgcgggtgctggaggcggtgggggcggcggccggcatccgcttcgagttcgccgag
gcgcccgtcggcggtgccgccgtcgatgccaccggcgaccccttcccgcccgagaccgag
cagctgtgcatggccgccgacgctatcctcctgggcgcggtgggaggcccccgctgggac
cgcgagccggttccccgccggccggagtcgggcctgctgcggctgcgcaaggccgtgggc
gcctacgccaacctgcggccggtgcgggttcatccggccctggcggggcgcggccccctg
cgcccggaggtggtgggcggcggcgttgacatcctgatcgtccgcgagctcaccggcggc
ctctactacggcgagcgcggcgtgcagcaggagcccttcggcgagcgggcctatgacacc
atggtctacaccacgcccgagatcgagcggatcgtgcgcatggctttccagctggcccgg
ggccggcggcggcgggtgatctccgtcgacaagagcaatgtgctggagacctcgcgcctc
tggcgccgggtgaccgaagccgtggcggaggacttccccgacgtggagctggagcacatg
ctggtggacaacgccgccatgcagctggtccgcaacccccagcgcttcgacgtgctggtg
accgagaacaccttcggcgacatcctgagcgatctgggcgcggccctggccggctccctg
gggctcctgccctcggccagcctggggctgccgggccggccgccgctgttcgagcccgtt
cacggctcggcgccggacatcgcgggccgggggatcgccaacccgctgggcgccatcgcc
tcggcggcgatgatgctccgtcacgccttcggcctccagcgggaggcccaggcggtcgag
gaggccatcgacgacctgctggccgcggggccgtggacgcccgacatcgcaccgcccggc
gccccggtggccagcacagaagacgtgggacgggccatcgcccggcgggtccgggagcgg
ctggcccccgggccgctggagccgctggggccggtggcggggcgggacggccggggcacg
caggacggccgcggctcccaggatggcagcgggctcgccggcgatccggtggcggcggtg
tggatcgccggcgaatacggcttccgaccgcttcctccggacgaaccggccccgccggcc
gcggcgcccgcggccaccggcacggtgcgcgccggtgaccctgcgaccggcgcatcccgc
gacgccatgaccccagacgccctggccaacggtccgaccgccgccggcgggaccgccgcc
gacacggccaccggcaccaacggcaccgcgacccggagcgagagtcctgtcaggacgcct
gcgcgccggggcaccggagcgggcaccacccgccgccgggcccgggctcggaagggagcg
tga
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