Thermoanaerobacter mathranii: Tmath_1477
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Entry
Tmath_1477 CDS
T01250
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tmt
Thermoanaerobacter mathranii
Pathway
tmt00300
Lysine biosynthesis
tmt00550
Peptidoglycan biosynthesis
tmt01100
Metabolic pathways
tmt01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tmt00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Tmath_1477
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Tmath_1477
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Tmath_1477
Enzymes [BR:
tmt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Tmath_1477
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF2608
Chordopox_G2
Motif
Other DBs
NCBI-ProteinID:
ADH61188
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Position
complement(1470255..1471640)
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AA seq
461 aa
AA seq
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MMELLIAEIVRATEGKLIKGSLKDKVIGISTDSRKVKKDELFIPLKGEKYDGEDFVKDAM
TKGAKAVLTARLDNIEYLRDFPFNVIYVNDTLEALHKIASYYRKKFNIPFVAVTGSTGKT
TTKDMIAQILSKKYKVLKTEGNFNNEIGLPLTIFNLENTHQIAVVEMGMSGFGEIRRLKN
IVKPQVAVFTNIGVAHIEKLGSRENILKAKTELIEDFKEENVIVLNADDDMLSKIPLQYS
SKYYRYGIKNGEIKACNIEKGEKGIKYTLKYKNLEKEIKLSIPGIHNVYNSLAAICVGLE
FGVDVDDMAEVLKDFQPGKMRLNIIEKGDIKIIDDAYNANPDSMKAALNVLRDFPGKRKI
AVLGDMLELGEYSVEAHREIGKLVADSHIDILITSGNTSKYIAEESKVCGMKENNIFVCN
TNEEVKEILKDIIKEGDLILVKGSRGMKMEQIVQFLQERVN
NT seq
1386 nt
NT seq
+upstream
nt +downstream
nt
atgatggaacttttaatagctgaaattgtaagggccacagagggaaaattgataaaagga
agtttaaaggataaagtaataggaatttcgactgattcaagaaaagtcaaaaaagatgaa
ttatttattcctttgaaaggagaaaaatatgatggagaagattttgtaaaagatgcgatg
acaaaaggtgctaaagcagtcctcactgccaggttagataatatagagtatttaagagat
tttccatttaacgttatttacgtaaatgatactttagaggctttacataagatcgcttct
tactatagaaaaaaattcaatatcccatttgttgctgtgacaggtagcactgggaaaact
actacaaaagatatgattgcgcaaatattgtctaaaaagtataaagtgttgaaaacagaa
ggtaattttaataatgaaataggtttgccattgacgatttttaatttggagaatactcat
caaattgcggtagtggaaatgggaatgagtggttttggagaaattaggaggttaaagaat
attgtaaagccgcaagtggcagtatttacaaatataggagttgctcatattgaaaaatta
ggttcaagggaaaatatattaaaagcaaaaacggaattgattgaagattttaaagaggaa
aatgtgattgtattaaatgcagatgatgatatgctatcaaaaattcctctgcaatattca
agtaagtattacagatatggtataaaaaatggagaaattaaggcttgcaatatagaaaaa
ggagaaaaaggtataaaatatactttgaaatataaaaatttagagaaagaaataaaactc
tcaatacctggtattcataatgtgtacaattctcttgctgctatttgtgttggattagag
tttggggttgatgtagatgacatggcggaggttttaaaagattttcaaccaggtaaaatg
agacttaatataatagaaaaaggtgacataaaaattattgatgacgcatataatgccaat
ccagattctatgaaagcagctttaaatgtcttgagggattttcctggcaaaagaaaaata
gcggttttaggagacatgctagaattaggggagtattcagtagaagcccacagagaaata
ggaaaattggtggcagatagccatatagatattttgataacttctggtaatacgtcgaaa
tatattgcagaagaatccaaggtttgtggaatgaaagagaataatatttttgtttgtaat
actaacgaagaagttaaggaaatattgaaagatattatcaaagaaggagatttaatttta
gtgaaaggttcaagaggtatgaaaatggagcaaatagtacaatttttgcaggagagggta
aactaa
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