Thermoanaerobacter mathranii: Tmath_1610
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Entry
Tmath_1610 CDS
T01250
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
tmt
Thermoanaerobacter mathranii
Pathway
tmt00290
Valine, leucine and isoleucine biosynthesis
tmt00620
Pyruvate metabolism
tmt01100
Metabolic pathways
tmt01110
Biosynthesis of secondary metabolites
tmt01210
2-Oxocarboxylic acid metabolism
tmt01230
Biosynthesis of amino acids
Module
tmt_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
tmt00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Tmath_1610
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Tmath_1610
Enzymes [BR:
tmt01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Tmath_1610
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
ComA
AAA_lid_5
Motif
Other DBs
NCBI-ProteinID:
ADH61317
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All DBs
Position
complement(1596154..1597716)
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AA seq
520 aa
AA seq
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MKNLRIYDTTLRDGVQGQGISFTVEDKLKIVKALDEFGVAYIEAGNPGSNPKDIEFFERV
KNIKLKNAKLIAFGSTRRANTTTEEDANVISLLNADTEVVTIFGKSWDFQVIEILKTTLE
ENLKMIYDTVKFFKDKGKSVIFDAEHFFDGYKQNPEYALKTLEVALEAGADSVCLCDTKG
GAFPMEVYEITKTVVDKFNTEVGIHCHNDNGMAVADSIMAVEAGAIQVQGTINGYGERCG
NANLCTLVPNLQLLMGYKCVPDENLKQLTHLARFVSEIANVTHDERAPFVGKNAFAHKAG
MHADAVNKNTYSYELIDPSLVGNSRTFLISEVAGRGAVLNAINEIDPTIKKNSPETKLIL
DRLKEMEYLGYQYENAGGSLELLIRKVLGRYKPAFNLKEFKVIVNEPSVNSVNSFAIIKV
EVDGVEEIAAADGDGPVHALDNAVRRVLERFYPQIKEMRLTDYKVRVLDSNSATAAKVRV
IIESTDGKDSWSTIGVSTDIIEASWRALVDSIEYKLNKEN
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
gtgaagaacctacgcatatacgatacaacattaagagacggagttcaaggacaaggtata
tcttttactgtggaagataaattaaaaatagttaaagcgcttgatgagtttggtgtggcc
tatattgaggcaggtaaccctgggtctaatcctaaagatattgaattttttgaaagagtt
aagaatattaaattaaaaaatgctaaattaattgcttttggtagtacaagaagagcaaat
acaactaccgaagaagatgctaatgtaatttcactcttaaatgctgacacagaggtagta
actatctttggcaagtcatgggattttcaagttatagaaattttgaaaaccactttagaa
gaaaacttaaaaatgatttatgatacagtaaagttttttaaagacaaaggtaagtcagtt
atatttgatgcagagcatttttttgatggttacaaacaaaatccagagtatgctttaaag
acattagaagtagcattagaggcgggagcagacagtgtatgcttgtgcgatacaaaaggc
ggagcttttcctatggaggtttatgaaataacaaaaactgttgtggataaatttaataca
gaagtagggatacactgccataatgataacggaatggctgttgcagattccataatggca
gttgaggcaggggcaatacaagtacaaggtacaataaacggttatggtgaaagatgtggc
aatgcgaatttatgtaccttggtaccgaatttgcaattacttatgggatataaatgtgtg
cctgatgaaaatctaaaacaattgactcatttagcgaggtttgtaagtgaaattgcaaat
gttactcacgatgaaagagcaccttttgtgggaaaaaacgcatttgcccataaagctgga
atgcatgctgatgctgtaaataaaaatacttactcttatgaactgattgacccgtcttta
gtgggaaatagcagaacctttttaatttctgaagttgctggaagaggagcagttttaaat
gctataaacgagatagacccaaccatcaaaaaaaattcacctgagacaaaattaattctt
gataggctaaaagaaatggagtatttggggtatcaatatgaaaatgcaggaggctcatta
gaacttttgataagaaaagtccttggaagatacaagccagcctttaatttaaaagaattt
aaagttattgtaaatgaaccttctgtcaatagtgttaattcttttgcaattataaaggtg
gaagtagatggagtggaagaaatagccgctgcggatggagacggaccagtgcatgccctt
gataatgctgtaagaagggttttggagagattttatccacagataaaagagatgaggttg
acagactataaagtgagggttttggattctaattctgcgactgctgctaaagtgagggtt
ataattgagtctacagacggaaaagattcttggagcacgattggagtttctacagatatt
attgaagctagttggagggcacttgttgattcaatagaatataaactaaataaggagaat
tga
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