Trichechus manatus latirostris (Florida manatee): 101342002
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Entry
101342002 CDS
T05135
Name
(RefSeq) DNA topoisomerase 2-alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
tmu
Trichechus manatus latirostris (Florida manatee)
Pathway
tmu01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
tmu00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
101342002
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
tmu03032
]
101342002
03036 Chromosome and associated proteins [BR:
tmu03036
]
101342002
Enzymes [BR:
tmu01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
101342002
DNA replication proteins [BR:
tmu03032
]
Eukaryotic type
DNA Topoisomerases
101342002
Chromosome and associated proteins [BR:
tmu03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
101342002
Centrosome formation proteins
Centriole proteins
101342002
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
101342002
NCBI-ProteinID:
XP_004378132
UniProt:
A0A2Y9DP98
LinkDB
All DBs
Position
Unknown
AA seq
1533 aa
AA seq
DB search
MEVSPLQPVNENMQINKIKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDIGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASKEYKKKFKQTWMDNMGKAGEMELKPFSGEDYTCITFQPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNTLPVKGFRSYVDMYLKDKVDETGNPLKVIHEQVNHRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQVKNFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQ
IQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTDCTLILTEGDSAKTLAVSGLGVVGRDK
YGIFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDEDSLKTLRYGRIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD
RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTAYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFKGTIE
ELASNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR
DFFELRLKYYGLRKEWLLGMLDAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDNEKETEKRDSVTDSGPTFNYLLDMPLWYLTKEK
KDELCKLRNEKEQELETLKRKSPSDLWREDLAAFIEELEIVEAKEKQDEQVGLPGKGGKG
KGKKAQMAEVLPSPSGRRVIPRVTIEMKAEAEKKIKRKIKSENTEGSPQEGSAEPESLKQ
RLEKKQKREPGNKTKKQTNLPFKPVKKGKKRNPWSDSESDMSDNESNFDLPPRETEPRRA
AKSKFTIDLDSEEDFSDFDEKAQDEDFVPSDVSPPKSKTSPKYTNKKLKPQKSAKSVMDI
DADDAKDNVLPSSSSPTADLPAETEIINPVSKKNVTVKKTAAKSQSSTSTTGTKKRAAPK
GTKKDSGLNSDVSQKKPGPAKSKNPRKRKPSTSDDSDSNFEKMISKAVTTKKSKGESDDF
QLDLDSAVAPRAKSVRAKKPIRYLEESDEDDLF
NT seq
4602 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcaccattgcagcccgtaaatgaaaatatgcaaatcaacaaaataaagaaa
aatgaagatgctaagaaaagactgtctatcgaaagaatctaccaaaagaaaacgcaattg
gaacatattttgctccgcccagacacctacattggctctgtggaattggtgacccagcaa
atgtgggtttacgatgaagatattggcattaactatagggaagttacttttgttcctggt
ttatacaaaatctttgatgagattctagtcaatgctgcggacaacaagcaaagggaccca
aaaatgtcctgtatcagagtcacaattgacccggaaaacaatttaattagtatatggaat
aacggaaaaggtattcctgttgttgaacacaaagttgagaaggtgtatgtcccagccctc
atctttggacagctgctaacttctagtaactatgatgatgatgaaaagaaagtaacaggt
ggtcgaaatggctatggagccaaactgtgtaacatattcagtaccaaattcactgtggaa
acagccagtaaagaatacaagaaaaaattcaaacagacatggatggataacatggggaaa
gctggcgagatggaactcaagccttttagtggagaagattatacatgtatcaccttccag
cctgatttgtctaagtttaaaatgcaaagcttggacaaagatattgttgcactgatggtt
aggagagcgtatgatattgctggatccactaaggatgtcaaagtctttcttaatggaaat
acactgccagtaaaaggattccgtagctatgtggacatgtatttgaaggataaggtagat
gaaactggcaacccattgaaagttatccatgaacaagtaaaccataggtgggaagtgtgc
ttaacgatgagtgaaaaaggttttcagcaaattagcttcgtcaacagcattgctacttcc
aagggaggcagacatgttgattatgtagctgaccagatagtgactaaacttgttgatgtt
gtgaagaagaagaacaagggtggtgttgccgtaaaagcacatcaggtgaaaaatcacatg
tggatttttgtgaatgccttgattgaaaacccaacctttgactctcagacaaaggaaaac
atgactttacaggtcaagaactttggatcaacatgccaattaagtgaaaaattcatcaaa
gctgcaattggctgtggtattgtagaaagcatactaaactgggtgaagtttaaggcccaa
atccagttaaacaagaagtgttcagctgtaaaacataacagaattaagggaattcccaaa
cttgatgatgccaatgatgcagggggccgaaactccactgattgtacgcttatcctgact
gagggagactcagctaaaactttggctgtttcaggccttggtgtggttggaagagacaaa
tatgggatttttcctcttagaggaaaaatactcaatgttcgagaagcttctcataaacag
ataatggaaaatgccgaaattaacaatatcattaagattgtgggtcttcagtacaagaaa
agctatgacgatgaagattcattgaagactcttcgttatgggaggataatgattatgaca
gatcaggaccaagacggttcccatatcaaaggcttgttgattaattttatccatcacaac
tggccttctcttctaagacatcgttttctggaagaatttatcacccccatcgtaaaggta
tctaaaaataagcaagaaatggcattctacagccttcctgaatttgaagaatggaaaagt
tctactccaaatcataaaaaatggaaagtcaagtattacaaaggtttgggcaccagcaca
tcaaaagaagctaaagaatactttgcagatatgaaaagacatcggattcaattcaaatat
tctggtcctgaagatgatgctgcaatcagcctggcctttagcaaaaaacagatagatgat
cgaaaggaatggttaactcattttatggaggatagaagacaacgaaagttgcttggactt
ccagaggattacttgtacgggcagactaccgcatatctaacctacaatgacttcataaac
aaggaacttatcctgttctcaaattctgataatgagagatctatcccatctatggtggat
ggtttgaaaccaggtcagagaaaggttttgtttacttgtttcaaacggaatgacaagcga
gaggtgaaggttgcccagttagctgggtcagtggctgagatgtcctcttatcatcatggt
gagatgtcattgatgatgaccattatcaatttggctcagaattttgtgggcagcaataat
ctgaacctcttgcagcctattggtcagtttggtaccaggctacatggtggcaaggactct
gctagtcctcgatacatcttcacaatgctcagccctttggctcggttgttatttccacca
aaagatgatcacacattaaagttcttatatgatgacaaccaacgcgttgagcctgaatgg
tacattcctattatacccatggtcctgataaacggtgctgaaggaatcggtactgggtgg
tcctgcaaaatccccaactttgatgttcgtgaagttgtgaataacatcaggcgactgatg
gatggagaagaacccttgccaatgcttccaagttacaagaacttcaagggtactattgaa
gaactggcttctaatcaatatgtaattagtggtgaagtggctattcttaattccacaacc
attgaaatctcagagcttcccatcagaacatggacccagacatataaagaacaggttcta
gagcccatgttgaatggcactgagaagacgcctcctctcataacagactatagggaatat
catacagataccactgtgaagtttgttgtgaagatgactgaagaaaaactagcagaggca
gagagagttggattacacaaagtattcaagctccagactagtctcacatgcaactctatg
gtgctttttgaccatgtaggctgtttaaagaaatatgatacagtgttggatattctaagg
gacttctttgaactcaggcttaaatattatggattacgaaaagaatggcttctaggaatg
cttgatgctgaatctgctaaactgaacaatcaagctcgctttattttagagaaaatagat
ggcaaaataatcattgaaaataaacctaagaaagaattaattaaagttctgattcagcgg
ggatatgattcggatcctgtaaaagcctggaaagaagctcagcaaaaggttccagatgaa
gaagaaaatgaagagagtgacaatgaaaaggaaactgaaaagagggactctgtaacagat
tctggaccaaccttcaattaccttcttgatatgcccctttggtatctaaccaaggagaag
aaggatgaactgtgcaaactaagaaatgaaaaagaacaagagctggaaacattgaagaga
aagagtccatcagatttgtggagagaagatctggctgcttttattgaagaactggagatt
gttgaagccaaggaaaaacaagatgaacaagtagggcttcctgggaaaggggggaaagga
aaggggaaaaaagcacaaatggccgaagttttgccttctccatctggcagaagagtcatc
ccccgagtgaccatagagatgaaagcagaggcagaaaagaaaattaaaaggaaaattaag
agtgaaaatactgaaggcagtcctcaagagggcagtgcggaaccagagagcctaaaacaa
agattagaaaagaaacagaaaagagaaccaggtaacaagacaaagaaacaaactaacttg
ccatttaaaccagtcaaaaaaggaaagaagagaaatccttggtctgattcggaatcagat
atgagtgataacgaaagtaactttgatctccctccacgagaaacagagccccggagagca
gcaaaatccaaattcacaattgatttggattcagaggaagatttctcagattttgatgaa
aaagctcaagatgaagattttgttccatcagatgttagtccacctaagtccaaaacttcc
ccaaaatatactaacaaaaaactgaagccacagaaaagtgccaaatcagtaatggacatt
gatgctgatgatgctaaggacaatgtactaccttcttcaagctctcctactgctgattta
ccagctgaaactgaaattataaacccagtttctaaaaagaatgtgacagtgaagaagacg
gcagcaaaaagtcagtcttccacctccactacaggcaccaaaaaaagggctgcaccaaaa
ggaaccaaaaaggattcaggcttgaattctgacgtctctcagaaaaagcctggtcctgcc
aaatccaaaaatccccgcaaaaggaagccatccacttctgatgattctgactctaatttt
gagaaaatgatttctaaagcagtgacaaccaagaaatccaagggagagagtgatgacttc
cagctggatttagactcagctgtggctcctcgggcaaaatctgtacgggctaagaaacct
ataagatacctggaagaatctgatgaagatgatctgttttga
DBGET
integrated database retrieval system
