| Entry |
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| Name |
(RefSeq) multidrug resistance-associated protein 1
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| KO |
| K05665 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] |
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| Organism |
tmu Trichechus manatus latirostris (Florida manatee)
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| Pathway |
| tmu04977 | Vitamin digestion and absorption |
| tmu04981 | Folate transport and metabolism |
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| Brite |
KEGG Orthology (KO) [BR:tmu00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
101342579
09132 Signal transduction
04071 Sphingolipid signaling pathway
101342579
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
101342579
04981 Folate transport and metabolism
101342579
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
101342579
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101342579
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:tmu02000]
101342579
Enzymes [BR:tmu01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.3 ABC-type glutathione-S-conjugate transporter
101342579
Transporters [BR:tmu02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
101342579
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1493 aa
MWAPCFYLCACFPFYFLHLSRHDQGYIQMTHLNKAKTALGFVLWIVCWADLFYSFWERSR
GVFLAPVLLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALLCAAAILRSRIM
AALKEDAQVDVFRDVTFYIYFSLVLVQLVLSCFSDRSPLFSETVNDPNPCPESSASFLSR
ITFWWITGMMIRGYRQPLEGTDLWSLNKEDTSEQVVPVLVKNWKKECAKSRKQPVKIVYS
SKDLAKPKGGSKVDVNEEAEALIIKSPQKERDPSLFKVLYKTFGPYFLMSFLFKALHDLM
MFAGPEILKLLIRFVNDKKAPDWQGYFYTALLFISACLQTLVLHQYFHICFVSGMRIKTA
VIGAIYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLTTYINMVWSAPLQVVLALYLL
WLNLGPSVLAGVAVMILMVPVNAVMAMKTKTYQVAHMKSKDSRIKLMNEILNGIKVLKLY
AWELAFKDKVLAIRKEELKVLKKSAYLAAVGTFTWVCTPFLVALCTFAVYVTVDKNNILD
AQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSQEELEPSSIERQPVKDG
GGSNSITVRNATFTWARSDPPTLSGITFSVPEGALVAVVGQVGCGKSSLLSALLAEMDKV
EGHVAIKGSVAYVPQQAWIQNDSLRGNILFGRPLQERYYKAVIKACALLPDLEILPSGDR
TEIGEKGVNLSGGQKQRVSLARAMYCNSDIYLFDDPLSAVDANVGKHIFENVVGPKGMLK
NKTRILVTHSISYLPQVDFIIVMSDGKISEMGSYQELLARDGAFAEFLRTYASVEQEQDA
EDEGLMGSSGPGKEAKLMENGMLVTDTTGKQLQRQLSNSSSYSGDTHKHHNSTAELQKPG
TQKEATWKLMEADKAQTGQVKLSVYWNYMKAIGLFISFLSVFLFLCNHVASLASNYWLSL
WTDDPIVNGTQVHTKVRLSVYGALGISQGIFVFGYSMTVSIGGILASRRLHLDLLHNVLR
APMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFNVIGACVVILLATPIAAIV
ILPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFSETLLGVSVIRAFEEQERFIRQS
DLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSL
QVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQTEEMAPPSSWPQVGRVEFRDY
SLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGLFRITESAGGQIIIDGVDI
AQIGLHSLRFRITIIPQDPVLFSGPLRMNLDPFNQYSDEEVWTSLELAHLKSFVSALPDK
LNHECSEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFDD
CTVLIIAHRLNTIMDCTRVIVLDRGEIREYGPPSDLLQQRGLFYSMAKDAGLV |
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| NT seq |
4482 nt +upstreamnt +downstreamnt
atgtgggcgccttgtttttacctctgtgcctgcttccccttctacttcctccatctctcc
cgacatgaccagggctacattcagatgacacatctcaacaaagccaaaactgccttgggg
tttgtgctgtggattgtctgctgggcagacctcttctactctttctgggaaagaagtcgg
ggtgtgttcctggccccagtgcttctggtcagtccaaccctcttgggcattaccatgctg
cttgctaccttcttaattcagcttgagagaagaaagggagtccagtcctcagggatcatg
ctcactttttggcttgtagccctactgtgtgctgctgccatcttgagatcccgaatcatg
gctgccttaaaagaggatgctcaagttgacgtgtttcgcgatgtcactttctacatttac
ttttccctcgtgctggttcagcttgtgttgtcctgtttctcagaccgctcgcccctgttc
tctgaaactgtcaacgaccctaacccttgcccggagtccagcgcctccttcctttctagg
atcaccttctggtggatcacagggatgatgatccggggctaccgccagccgctggaaggc
acagacctctggtccctaaacaaggaagacacttcagagcaagttgtgcctgttttggtg
aagaactggaagaaggaatgtgccaagtctagaaagcagccggtgaagatcgtgtactcc
tccaaggacctggccaagccaaaagggggctccaaggtggatgtgaacgaggaggcggag
gctttgatcatcaagtccccccagaaggagcgggacccatccctgttcaaggtgttatac
aagaccttcggaccctacttcctcatgagcttcttatttaaggcgctccatgacctgatg
atgtttgccggtccggaaatcttaaagctgctcatcagatttgtcaatgacaagaaggcc
ccggactggcagggctacttctacacagcacttctcttcatcagcgcctgcctccagacc
cttgtgctgcaccagtacttccatatctgctttgtcagtggcatgaggatcaagaccgcc
gtcattggggccatctaccggaaggccctggtgatcacaaattcagccagaaagtcctcc
acggttggggagattgtcaacctcatgtctgtggatgcccagcggttcatggacttgacc
acgtacattaacatggtctggtcagcccctctgcaagtcgtccttgctctctacctcctg
tggctgaacttgggcccatctgtcctggccggggtggctgtaatgatcctcatggttccc
gtcaacgctgtgatggcaatgaagaccaagacctatcaggtggctcacatgaagagcaaa
gacagtcggattaagctgatgaatgaaattctgaatgggatcaaggtactaaagctttac
gcctgggagctggctttcaaggataaggtgttggccatcaggaaggaagagctgaaagtg
ctgaagaagtctgcttacctggcagctgtggggaccttcacctgggtctgcacacctttc
ctggtggccctgtgtacatttgccgtctacgtgactgtcgacaagaacaacatcctggac
gcccagaaagccttcgtgtccttggccttgttcaacatcctgcggttccccctgaacatt
ctccccatggtcatcagcagcatcgtgcaggcgagtgtctccctgaaacgcctcaggatc
ttcctctcccaggaggagctggagcccagcagcatcgaacggcagcctgtcaaagatggt
gggggctcgaacagcatcaccgtgaggaacgcaaccttcacctgggccaggagcgacccg
cccacgctgagtggcattaccttctccgttccggaaggtgccttggtggccgtggtgggc
caggtgggctgtggaaagtcgtctctgctctcagcactgttggccgagatggacaaagtg
gaggggcacgtggctatcaagggctcagtggcctacgtcccccagcaggcctggatccag
aatgattccctccgaggaaatatcctcttcggacgcccgttgcaggagcggtattacaag
gccgtgatcaaggcctgtgccttgctcccagacctggagatcctgccctctggggaccgg
acagagattggtgagaagggcgtgaacctgtctgggggccagaagcaacgcgtgagcctg
gcccgggccatgtactgcaactcggacatctacctctttgacgaccccctctcggcggtg
gatgccaacgtcggaaagcacatatttgaaaatgtagtgggccccaaggggatgctgaag
aacaagacgcggatcctggtcacacacagcatcagctacctgccacaggtggatttcatc
atcgtcatgagtgacggcaagatctccgagatgggctcctaccaggagctgctggcccgg
gacggggccttcgccgagttcctgcgcacctatgccagtgtggagcaggagcaggacgca
gaggacgaggggttaatgggcagcagtggtccagggaaggaggcgaagctgatggagaac
ggaatgctggtgacggacaccacggggaagcagctgcagagacagctcagcaattcctcc
tcctacagcggggacacgcacaaacaccacaacagcaccgcggagctgcagaaacctggg
acacagaaggaggccacctggaagctgatggaggcagacaaggctcagacagggcaggtc
aagctctccgtgtactggaactacatgaaggccattggactcttcatctcctttctgagc
gtcttcctcttcttgtgtaaccacgttgcctccctggcttctaactactggctcagtctc
tggactgatgaccccattgtcaacgggacccaggtgcacaccaaagtccggctgagcgtc
tacggagccctgggcatttcccaaggtatctttgtgtttggctactccatgacagtgtcc
atcgggggcatcttggcctcccgccgcctgcacctggatctgctgcacaatgtcctccgg
gcacctatgagtttcttcgagcggacgcccagtgggaacctggtgaaccgcttctccaag
gagttggacacggtggactcaatgatcccgcaggttatcaagatgttcatgggctccctg
ttcaatgtcattggcgcctgcgtcgtcatcctgctggccacgcccattgccgccattgtc
atcctgcccctgggcctcatctacttcttcgtccagaggttctacgtggcctcctcccgg
cagctgaagcgccttgagtcggtcagccgctccccagtatactcccacttcagcgagacc
ctgttgggggtcagcgtcatccgtgcctttgaggagcaggaacgcttcatccgccagagc
gacctgaaggtggacgagaaccagaaggcctactaccccagcatcgtggccaataggtgg
ctggctgtgcggctggagtgtgttggcaactgcattgtgctctttgcggccctgttcgca
gtgatctcccggcacagcctaagtgccggcttggtcggcctctctgtgtcttactcgttg
caggtgacgacatacctgaactggctggtgcggatgtcatccgagatggagaccaacata
gtggctgtggagcgactcaaggagtactcagaaactgagaaggaggctccctggcagacg
gaggagatggctccacccagcagctggccccaggtgggccgagtggaattccgggactac
agcctgcgttaccgagaggacctggacttagtgctcaagcacatcaacgtcaccatcgag
gggggagagaaggttggcatcgtggggcggacaggagccgggaagtcatccctgaccctg
ggcttgtttcggatcaccgagtcggccggaggacagatcattatcgacggcgtcgacatt
gcccagatcggcctgcacagcctgcgcttcaggatcaccatcatcccccaggaccccgtt
ttgttttcgggccccctccgcatgaacctggacccgttcaaccagtactcggacgaagag
gtctggacgtcactggagctggctcacctgaagagcttcgtgtcagcccttccagataag
ctgaaccacgagtgctcggaaggtggggagaacctgagtgttgggcagcgccagcttgtg
tgcctggcccgggccctgctgaggaagacgaagatcctggtgttggacgaggccacggcg
gctgtggacctggaaacagacgacctcattcagtccaccatccggacccagtttgacgac
tgcactgtcctcatcattgctcaccggctcaacaccatcatggactgcacaagggtgatc
gtcctggacagaggggagatccgagagtatggccccccctctgacctcttgcagcagcga
ggcctgttctacagcatggccaaagatgctggcttggtgtga |
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