KEGG   Trichechus manatus latirostris (Florida manatee): 101343535
Entry
101343535         CDS       T05135                                 
Name
(RefSeq) ribosomal protein S6 kinase beta-2 isoform X1
  KO
K04688  ribosomal protein S6 kinase beta [EC:2.7.11.1]
Organism
tmu  Trichechus manatus latirostris (Florida manatee)
Pathway
tmu01521  EGFR tyrosine kinase inhibitor resistance
tmu01522  Endocrine resistance
tmu04012  ErbB signaling pathway
tmu04066  HIF-1 signaling pathway
tmu04140  Autophagy - animal
tmu04150  mTOR signaling pathway
tmu04151  PI3K-Akt signaling pathway
tmu04152  AMPK signaling pathway
tmu04211  Longevity regulating pathway
tmu04213  Longevity regulating pathway - multiple species
tmu04350  TGF-beta signaling pathway
tmu04371  Apelin signaling pathway
tmu04666  Fc gamma R-mediated phagocytosis
tmu04714  Thermogenesis
tmu04910  Insulin signaling pathway
tmu04931  Insulin resistance
tmu05163  Human cytomegalovirus infection
tmu05165  Human papillomavirus infection
tmu05170  Human immunodeficiency virus 1 infection
tmu05200  Pathways in cancer
tmu05205  Proteoglycans in cancer
tmu05207  Chemical carcinogenesis - receptor activation
tmu05210  Colorectal cancer
tmu05212  Pancreatic cancer
tmu05221  Acute myeloid leukemia
tmu05224  Breast cancer
tmu05225  Hepatocellular carcinoma
tmu05226  Gastric cancer
tmu05231  Choline metabolism in cancer
tmu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:tmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    101343535
   04350 TGF-beta signaling pathway
    101343535
   04371 Apelin signaling pathway
    101343535
   04066 HIF-1 signaling pathway
    101343535
   04151 PI3K-Akt signaling pathway
    101343535
   04152 AMPK signaling pathway
    101343535
   04150 mTOR signaling pathway
    101343535
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101343535
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    101343535
  09152 Endocrine system
   04910 Insulin signaling pathway
    101343535
  09149 Aging
   04211 Longevity regulating pathway
    101343535
   04213 Longevity regulating pathway - multiple species
    101343535
  09159 Environmental adaptation
   04714 Thermogenesis
    101343535
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101343535
   05205 Proteoglycans in cancer
    101343535
   05207 Chemical carcinogenesis - receptor activation
    101343535
   05231 Choline metabolism in cancer
    101343535
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101343535
  09162 Cancer: specific types
   05210 Colorectal cancer
    101343535
   05212 Pancreatic cancer
    101343535
   05225 Hepatocellular carcinoma
    101343535
   05226 Gastric cancer
    101343535
   05221 Acute myeloid leukemia
    101343535
   05224 Breast cancer
    101343535
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101343535
   05163 Human cytomegalovirus infection
    101343535
   05165 Human papillomavirus infection
    101343535
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    101343535
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101343535
   01522 Endocrine resistance
    101343535
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tmu01001]
    101343535
Enzymes [BR:tmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     101343535
Protein kinases [BR:tmu01001]
 Serine/threonine kinases: AGC group
  RSK family [OT]
   101343535
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 Seadorna_VP7
Other DBs
NCBI-GeneID: 101343535
NCBI-ProteinID: XP_004383713
UniProt: A0A2Y9DYE6
LinkDB
Position
Unknown
AA seq 482 aa
MAAVFDLDLETEEGSEGEGEPELSPADVCPLAELRSAGLEPVGHYEEVELTETSVNLGPE
RIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVCNAKDTAHTRAER
NILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITL
ALGHLHSQGIIYRDLKPENIMLNSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEI
LVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIVKGKLVLPPYLTPDARDLV
KKFLKRNPSQRIGGGPGDGADVQRHPFFRHINWDDLLARRVDPPFRPCLQSEEDVSQFDT
RFTRQTPVDSPDDSALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRT
PISPLKFSPFEGFRPSPGPSEPMEPILPPLLPPPPPSSTAPLPIRPPSGTKKSKRGRGRP
GR
NT seq 1449 nt   +upstreamnt  +downstreamnt
atggcagccgtgttcgacctggacctggagacggaggagggcagcgagggcgagggcgag
ccagagctcagccctgcggacgtgtgtccccttgccgagttgaggtcggctggcctggag
cctgtgggacactatgaggaggtggagctgaccgagaccagtgtcaacctcggccccgag
cgcattgggccccactgctttgaactgctgcgtgtactgggcaaggggggctatggcaag
gtgttccaggtgcgaaaggtgcaaggtaccaacttgggcaaaatatatgccatgaaagtc
ctgaggaaggccaaaattgtgtgcaacgccaaggacacagcgcacacacgggcggagcgg
aacattctagagtctgtgaagcaccccttcattgtggaactggcctatgccttccagact
ggtggcaagctctacctcatcctggagtgcctcagtggcggcgagctcttcacgcatctg
gagcgagaaggcatcttcctggaggacacagcctgcttctacctggcagagatcactctg
gcccttggccacctgcactcccaaggcatcatctaccgggacctcaaacctgagaacatc
atgctcaacagccagggtcacatcaagctgacggactttgggctctgcaaggagtccatt
cacgagggtgccgtcacccacaccttctgcggcaccatcgagtacatggcccctgagatt
ctggtgcgcagtggccacaaccgggcggtggactggtggagcctgggggccctgatgtac
gacatgctcactggatcgccaccctttaccgcagagaaccggaagaaaaccatggacaag
atcgtcaaggggaagctggtgctgcccccctacctcaccccggatgcccgggacctcgtc
aaaaagtttctgaagcggaatcccagccaacggattgggggtggcccaggggacggcgct
gatgtgcagaggcaccccttcttccggcacatcaactgggacgatctcctagcccgccgc
gtggatccccccttcaggccctgtctgcagtcggaggaggacgtgagccagtttgacacc
cgcttcacgcggcagacgccagtggacagtcccgacgactcggcccttagtgagagtgcc
aaccaggctttcctgggcttcacgtacgtggcaccctccgtcctggacagcattaaggag
ggcttctccttccagcccaagctgcgctcccccaggcgcctcaacagcagcccccggacc
cctatcagccccctgaagttctccccttttgaggggttccggcccagccctggcccatcg
gagcccatggagcccattctacctccactcctgccaccaccgccaccctcgagcactgcc
cctctccctatccgtcccccctcagggaccaagaagtccaagaggggccgtgggcgccct
gggcgctag

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