Trichechus manatus latirostris (Florida manatee): 101347136
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Entry
101347136 CDS
T05135
Name
(RefSeq) hypoxia-inducible factor 1-alpha isoform X1
KO
K08268
hypoxia-inducible factor 1 alpha
Organism
tmu
Trichechus manatus latirostris (Florida manatee)
Pathway
tmu04066
HIF-1 signaling pathway
tmu04137
Mitophagy - animal
tmu04140
Autophagy - animal
tmu04148
Efferocytosis
tmu04659
Th17 cell differentiation
tmu04919
Thyroid hormone signaling pathway
tmu05167
Kaposi sarcoma-associated herpesvirus infection
tmu05200
Pathways in cancer
tmu05205
Proteoglycans in cancer
tmu05208
Chemical carcinogenesis - reactive oxygen species
tmu05211
Renal cell carcinoma
tmu05230
Central carbon metabolism in cancer
tmu05231
Choline metabolism in cancer
tmu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
tmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
101347136
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101347136
04137 Mitophagy - animal
101347136
04148 Efferocytosis
101347136
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
101347136
09152 Endocrine system
04919 Thyroid hormone signaling pathway
101347136
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101347136
05205 Proteoglycans in cancer
101347136
05208 Chemical carcinogenesis - reactive oxygen species
101347136
05230 Central carbon metabolism in cancer
101347136
05231 Choline metabolism in cancer
101347136
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101347136
09162 Cancer: specific types
05211 Renal cell carcinoma
101347136
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
101347136
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
tmu03000
]
101347136
Transcription factors [BR:
tmu03000
]
Eukaryotic type
Basic helix-loop-helix (bHLH)
Factors with PAS domain
101347136
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
bHLH_HIF1A
PAS_3
PAS_11
HIF-1a_CTAD
PAS
HIF-1
PAS_9
PAS_4
HLH
DDRGK
Motif
Other DBs
NCBI-GeneID:
101347136
NCBI-ProteinID:
XP_004370983
UniProt:
A0A2Y9DAX9
LinkDB
All DBs
Position
Unknown
AA seq
823 aa
AA seq
DB search
MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVM
RLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYM
GLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGPVKKGKEQNTQRSFFLRMKCTLTSRGR
TMNIKSATWKVLHCTGHIHVYDTNSNQSQCGYKKPPMTCLVLICEPIPHPSNIEVPLDSK
TFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQV
TTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECV
LKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGGNDTET
DDQQLEEVPLYNDVMLPSSSEKLQNINLAMSPLPASETPKPLRSSADPALNQEVALKLEP
NPESLELSFTMPQIQDQPASPSDGSTRQSSPEPNSPSEYCFDVDSDMVNEFKLELVEKLF
AEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSASPQSASTISVFQ
QTQMQEPAVIANTSTATTDELKTVTKDGMEDIKILIASPSPTHVLKETTSATTSPYSDTQ
SRTASPSRAGKGVIEQTEKSHPRSPNLLSVTLSQRTTVPEEELNPKILALQNAQRKRKME
HDGSLSQAVGIGTLLQQPDDRATTTSLSWKRVKGCKSSEQNGMEQKTIILIPSDLACRLL
GQSMDESGLPQLTSYDCEVNAPVQGSRNLLQGEELLRALDQVN
NT seq
2472 nt
NT seq
+upstream
nt +downstream
nt
atggagggcgccggcggcgcgaacgacaagaaaaagattagttctgaacgccgaaaagaa
aagtctcgagatgcagccagatctcggcgaagtaaagagtcggaagttttttatgagctt
gctcatcagttgcctcttccccataatgtcagctcgcatcttgataaagcctctgttatg
aggcttaccattagctacttgcgtgtgaggaaacttctagatgctggtgatttggatatt
gaagatgaaatgaaggcacagatgaattgcttttatctgaaagccctagatggttttgtt
atggttctcacagatgatggtgacatgatttacatttctgataatgtgaacaaatacatg
ggattaactcagtttgaactaactggacacagtgtgtttgattttactcatccatgtgac
catgaggaaatgagagaaatgcttacccacagaaatggccctgtgaaaaagggtaaagag
caaaacacacaacgaagcttttttctcagaatgaagtgtaccctaactagccgggggaga
actatgaacataaagtctgcaacatggaaggtacttcattgcacaggccatattcatgta
tacgatactaacagtaaccagtctcagtgcgggtataagaaaccacctatgacatgtttg
gtgctgatatgtgaacctattcctcatccatcaaatattgaagttcctttagatagcaag
acttttctcagtcgtcatagcctggacatgaaattttcttattgtgatgaaagaattact
gaattgatgggatatgagccagaagaacttttgggtcgctcaatttatgaatattatcac
gctttggactcggatcatctgaccaaaactcatcatgatatgtttactaaaggacaagtc
accacaggacagtacaggatgcttgccaaaagaggtggatatgtctgggttgaaactcaa
gcaaccgttatatacaacactaagaattctcaaccacaatgtattgtatgtgtaaattat
gttgtgagtggtataattcagcacgacttgattttctcccttcaacaaacagaatgtgtc
ctcaaacctgttgagtcttcagatatgaaaatgactcagctattcaccaaagttgaatca
gaagatacaagtagtctctttgataaacttaagaaggaacctgatgctttaactttgctg
gccccagctgctggagacacaatcatatctttagattttggtggcaatgacacagaaact
gatgaccagcaacttgaggaagttcccttgtataatgatgtaatgctcccctcatccagt
gaaaaattacagaatataaatttggcaatgtctccattacctgcctctgaaactccaaag
ccacttcgaagtagtgctgaccctgcactcaatcaagaagttgcattaaaattagaacca
aatccagagtcgctggaactttcttttaccatgccccagattcaggatcagccagccagc
ccttctgatggaagcactagacaaagttcaccagagcctaatagccccagtgaatattgt
tttgatgtggacagtgatatggttaatgaattcaagttggaattggtagagaaacttttc
gctgaagacacggaagcaaagaatccattttccactcaggacactgatttagacttggag
atgttagccccctacatcccaatggatgatgacttccagttacgttcattcgatcagtta
tcaccattagaaagcagctctgcaagccctcaaagtgcaagcacaatttcagtattccag
cagactcaaatgcaggaacctgctgttatcgccaacacttccactgccaccactgatgaa
ttaaaaacagtgacaaaagacggtatggaagacattaaaatattgattgcatctccatct
cctacccacgtacttaaagaaactactagtgccacaacatcaccatatagtgatacacaa
agtcggacagcctcaccaagcagagcaggaaaaggagtcatagaacagacagaaaaatct
catccaagaagccctaacctgttatctgtcactttgagtcaaagaactactgttcctgag
gaagagctaaatccaaagatactagctttgcagaatgctcagagaaagcgaaaaatggaa
catgatggttcgctttctcaagcagtaggaattggaacattattacaacagccagatgat
cgtgcaactactacatcactttcttggaaacgtgtaaaaggatgcaaatctagtgaacag
aatggaatggagcaaaagacaattattttaataccctcagatttagcatgtagactgctg
gggcaatcaatggatgagagtggattaccacagttgaccagttatgattgtgaagttaat
gctcctgtacaaggcagcagaaacctactgcagggtgaagaattactcagagctttggat
caagttaactga
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