Trichechus manatus latirostris (Florida manatee): 101349482
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Entry
101349482 CDS
T05135
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
tmu
Trichechus manatus latirostris (Florida manatee)
Pathway
tmu00270
Cysteine and methionine metabolism
tmu00480
Glutathione metabolism
tmu01100
Metabolic pathways
tmu01240
Biosynthesis of cofactors
tmu04216
Ferroptosis
Module
tmu_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
tmu00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
101349482
09106 Metabolism of other amino acids
00480 Glutathione metabolism
101349482
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
101349482
Enzymes [BR:
tmu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
101349482
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Paralog
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
101349482
NCBI-ProteinID:
XP_004386871
UniProt:
A0A2Y9E467
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All DBs
Position
Unknown
AA seq
637 aa
AA seq
DB search
MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKKVQLVLSGEEVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSLLEENQAVCTITSFPRLGCPGFTLPEYKPNPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIEAFPEDDEAARASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSECGEKYNDINLTIDKEIYEQLLQ
EGIDRLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
QGMFYFRKDICKGGNAMVDGYGKAQNSAELAPEEYTLMSIDTIINGKEGVFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFITNHPDYKQDSVITDKINYS
LILKCNQIANELCECPELLGSSFRKVKYSRSKTDSSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccaaggctcgccactgagctgggaggagaccaagcgccacgctgac
cacgtgcggcggcacgggatcctccagttcttgcacatctaccatgctgtcaaggaccgg
cacaaggacgtgctcaagtggggcgacgaggtggaatacatgttggtctcttttgatcat
gaaaataaaaaagtccagttggtcctgtctggagaggaagttcttgaaactctgcaagaa
aagggggaaaggacaaacccaaaccatcctaccctttggagaccggagtacgggagttac
atgatcgaggggacacctggacagccatacggaggaacgatgtccgagttcaacacagtt
gaggacaacatgagaaaacgtcggaaggaggctacttctctgttagaagaaaatcaggct
gtttgcactataacttcatttcctagattaggctgtcctgggttcacactgcctgagtat
aaacccaacccggtggaaggaggagcttccaagtccctcttctttccagatgaagcaatt
aacaagcatccccgcttcagtaccctaacaagaaatatccgacataggagaggagaaaaa
gttgtcatcaatgtaccaatatttaaggacaagaatacaccatctccatttatcgaagca
tttcctgaggatgatgaggcagcaagggcttctaagcccgatcatatttacatggatgcc
atgggatttgggatgggcaattgctgtcttcaggtgacattccaagcctgcagcatatct
gaagccagatacctgtatgatcagttggctacaatctgtccaattgttatggctttgagt
gctgcgtctccattttaccgaggctatgtgtcagacattgattgtcgctggggagtgatt
tctgcatctgtagatgatagaactcgggaggagagaggactggagccacttaagaacaat
aactataggatcagtaaatcccgttatgattcaatagacagttacttatctgagtgtggt
gagaaatacaatgatatcaacttgacaatagataaagaaatctacgaacaacttttgcag
gaaggcattgaccgtctcctggcccagcatgttgctcatctctttattagagacccactg
actctgtttgaggagaaaatacatcttgatgatgccaatgagtctgatcattttgagaat
attcagtccacaaattggcagacgatgagatttaagccccctcctccaaactcagatatc
ggatggagagtagaatttcggcccatggaggttcagttaacagactttgagaactctgca
tatgtggtgtttgtggtactccttaccagagtgatcctttcatacaagttggattttctc
attccactctcaaaggtggatgaaaacatgaaagtggcacagaaacgagatgctgtcctg
cagggaatgttttatttcaggaaagacatttgcaaaggtggcaatgctatggtggacggg
tatggcaaggcccagaacagcgctgagcttgcccccgaggagtacactttaatgagcata
gacaccatcatcaacgggaaggaaggtgtgtttcctgggctgatcccaattctgaactct
taccttgaaaatatggaagtggatgtggacaccagatgtagtattctaaactacctaaag
ctcattaagaagagagcatctggagaactaatgacagttgccagatggatgagggaattt
atcacaaaccatcctgactacaagcaagacagtgtcataactgataaaataaactatagc
cttattttgaagtgtaaccaaattgcaaatgaattatgtgagtgcccagagttacttgga
tcttcatttaggaaagtaaaatatagcagaagtaaaactgactcttccaactag
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