Trichechus manatus latirostris (Florida manatee): 101349879
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Entry
101349879 CDS
T05135
Name
(RefSeq) fumarate hydratase, mitochondrial
KO
K01679
fumarate hydratase, class II [EC:
4.2.1.2
]
Organism
tmu
Trichechus manatus latirostris (Florida manatee)
Pathway
tmu00020
Citrate cycle (TCA cycle)
tmu00620
Pyruvate metabolism
tmu01100
Metabolic pathways
tmu01200
Carbon metabolism
tmu04934
Cushing syndrome
tmu05200
Pathways in cancer
tmu05211
Renal cell carcinoma
Module
tmu_M00009
Citrate cycle (TCA cycle, Krebs cycle)
tmu_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
tmu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
101349879
00620 Pyruvate metabolism
101349879
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101349879
09162 Cancer: specific types
05211 Renal cell carcinoma
101349879
09167 Endocrine and metabolic disease
04934 Cushing syndrome
101349879
Enzymes [BR:
tmu01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.2 fumarate hydratase
101349879
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Lyase_1
FumaraseC_C
Motif
Other DBs
NCBI-GeneID:
101349879
NCBI-ProteinID:
XP_004375908
UniProt:
A0A2Y9DKJ6
LinkDB
All DBs
Position
Unknown
AA seq
508 aa
AA seq
DB search
MNPAVRFFARRGRLVRPAASASAPGLGGAAVLPFRPSNAARMASQSSYRIEYDTFGELKV
PNDKYYGAQTVRSTMNFKIGGVTERMPAPVIKAFGILKHAAAEVNQDYGLDPKIANAIMK
AADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKKPVHPNDHVN
KSQSSNDTFPTAMHIAAATEVHEVLLPGLQKLHDALDAKSKEFAQIIKIGRTHTQDAVPL
TLGQEFSGYVQQVKYAMTRVKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTG
LPFVTAPNKFEALAAHDALVELSGAMNTAACSLMKIANDIRFLGSGPRSGLGELILPENE
PGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARL
LGDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHNNGSTL
KETAIELGYLTAEQFDEWVKPADMLGPK
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
atgaacccagcagtcagattcttcgcgcgccgcggtcgcctcgtgcggcctgcagcctca
gcctccgctcccggcctcggtggcgcggctgttctcccattccggccctcgaacgccgct
cgaatggcaagccaaagttcctatcggatagaatatgacacttttggtgaactcaaggtc
ccgaatgataagtattatggcgcccagacagtgagatctacaatgaactttaagattgga
ggtgtgacagaacgcatgccagccccagttattaaagcttttggcatcttaaagcatgca
gctgctgaagtaaaccaggattatggtcttgatccaaagattgctaatgcaataatgaag
gcagcagatgaggtagccgaaggtaaattaaatgatcattttcctctcgtggtatggcag
actggatcaggaacccagacaaatatgaatgtaaatgaagtcattagcaatagagcaatt
gaaatgttaggaggcgaacttggcagcaagaaacccgtccatcctaatgatcatgttaat
aaaagccagagctcaaacgatacttttcctactgcaatgcatattgctgctgcaacagaa
gttcatgaagtgctgttaccaggactacagaagctacatgatgctcttgatgcaaaatcc
aaagagtttgcccagatcatcaaaattgggcgtactcatacacaggatgctgttcctctt
actcttggacaggaatttagtggttatgttcaacaagtgaaatacgcaatgacaagagta
aaagctgccatgccaagaatctacgagctcgcagctggaggcactgctgtgggtactggt
ttaaatactagaattggctttgcagaaaaggttgctgcaaaagtggctgcactcacaggc
ttgcctttcgtcacagccccaaataaatttgaagctctggctgctcacgatgccttggtt
gaactcagtggagccatgaacactgccgcttgcagtctgatgaagatagcaaatgatatt
cgttttctgggttctggtcctcgatcaggtctgggagaactgatcttgcctgaaaatgaa
ccaggaagcagtatcatgccaggaaaggtgaaccccacccagtgtgaagcgatgaccatg
gttgccgcacaagtcatggggaatcacgttgctgttactgttggaggcagcaatggacat
tttgagttgaatgttttcaagccaatgatgattaaaaatgtgttacactcagcaaggcta
ctgggggatgcttccgtttccttcacagaaaactgcgtggtaggaatccaggccaacaca
gaaagaatcaacaagctaatgaatgagtctttaatgttggtgacggcacttaatccccat
atagggtatgacaaggcagcaaagattgctaagacagcacacaacaatggatcaacctta
aaggaaactgccattgaacttggctatctcacagcagagcagtttgatgagtgggtgaaa
cctgcagacatgctggggccaaagtag
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