Trichechus manatus latirostris (Florida manatee): 101352446
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Entry
101352446 CDS
T05135
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
tmu
Trichechus manatus latirostris (Florida manatee)
Pathway
tmu04140
Autophagy - animal
tmu04141
Protein processing in endoplasmic reticulum
tmu04210
Apoptosis
tmu04932
Non-alcoholic fatty liver disease
tmu05010
Alzheimer disease
tmu05012
Parkinson disease
tmu05014
Amyotrophic lateral sclerosis
tmu05016
Huntington disease
tmu05017
Spinocerebellar ataxia
tmu05022
Pathways of neurodegeneration - multiple diseases
tmu05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
tmu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
101352446
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101352446
09143 Cell growth and death
04210 Apoptosis
101352446
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
101352446
05012 Parkinson disease
101352446
05014 Amyotrophic lateral sclerosis
101352446
05016 Huntington disease
101352446
05017 Spinocerebellar ataxia
101352446
05022 Pathways of neurodegeneration - multiple diseases
101352446
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101352446
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101352446
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tmu01001
]
101352446
Enzymes [BR:
tmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101352446
Protein kinases [BR:
tmu01001
]
Serine/threonine kinases: Other
IRE family
101352446
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
101352446
NCBI-ProteinID:
XP_004374271
UniProt:
A0A2Y9DGQ0
LinkDB
All DBs
Position
Unknown
AA seq
976 aa
AA seq
DB search
MPVRRLLLLLLALVLPVSEIFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKED
PVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPDLVQASPCRSSDGILYMG
KKQDIWYVIDLLTGEKQQTLSSAFAESLCPSTSLLYLGRTEYTITMYDTKNRELRWNATY
FDYAASLPEDDMDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRK
VMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLMPTLYVGKYSTSLYASPSM
VHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKNKLNYLRNYW
LLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENAPTTVT
QDVEEKFTHAPAKPEAPVDSMLKDMATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQF
QKELEKIQLLQQQQLPFHPPVDPAQDAELLDTLGPYSESSGTSSPSTSPRASNHSLHSSG
SASKAGISPFPDQDDEDEETSMVLVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRI
LPECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHL
GLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVG
RHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQR
QANILLGAYSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWGLEKQLQF
FQDVSDRIEKESLDGLIVKQLEKGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLL
RAMRNKKHHYRELPTEVRETLGSLPDDFVRYFTSRFPHLLLHTYRALELCSHERLFQPYY
CHEPPEPQPLLPPDAL
NT seq
2931 nt
NT seq
+upstream
nt +downstream
nt
atgccggtccggcggctgctgctgctgctgctggcgctggtgctgcctgtctctgagatt
tttggaagtaccagcacagtgacacttcctgaaaccttgttatttgtgtcaaccttggat
ggaagtttgcatgctgtaagcaagcggacaggctcaatcaaatggactttaaaagaagat
ccagtcctgcaggttccaacccacgttgaagagcctgcattcctcccagatcccaatgat
ggcagcctgtatacactcgggggcaagaataatgaaggcctgacgaaacttccctttacc
atcccagatttggtgcaggcatctccatgccgaagttcagatggaattctctacatgggt
aaaaagcaggacatttggtatgttattgacctcctgaccggggagaagcagcagactttg
tcatcggccttcgcagaaagtctctgtccatccacctctcttctgtatcttgggcgaaca
gagtacaccatcaccatgtatgacaccaaaaaccgagagctccggtggaacgccacctac
tttgactatgcagcctcgctgcctgaggacgacatggactacaagatgtcccactttgtg
tccaatggcgacgggctggtggtgaccgtggacagtgaatctggggacgtgctatggatc
caaaactatgcctcgcctgtggtggccttttatgtttggcagcgggagggtctgaggaag
gtgatgcacatcaatgttgccgtggagaccctgcgctatctgaccttcatgtctggggag
gtgggacgcatcaccaagtggaagtacccgttccccaaggagacggaggccaagagcaag
ctgatgcccaccttgtatgttgggaaatactctaccagcctgtacgcctccccctccatg
gtacacgagggggtcgctgtcgtgccccgaggcagcactcttcctttgttggaaggcccc
cagaccgacggtgtcaccatcggggacaaaggggagtgtgtgatcacacccagcacggac
ctaaagtttgaccctggactcaaagggaagaacaagctgaattacctgaggaattactgg
cttctgataggacaccatgaaactccgctgtctgcatcgaccaagatgctggagaggttc
cccaacaatctgcccaaacatcgggaaaatgtgattcctgccgattctgagaaaaagagc
tttgaggaggtcatcaacctagttgaccagacttcggaaaatgcgcccaccacagtgact
caggatgtggaagagaagtttacacatgcccctgccaagcctgaggcccccgtggactcc
atgctcaaggacatggccaccatcatcctgagtaccttcctcctgattggctgggtggcc
ttcatcatcacctaccccctgagcatgcatcagcagcagcagctccagcaccagcagttc
cagaaggaactggagaaaatccagctcctgcagcagcagcagctgcctttccacccacct
gtggacccagcacaggatgcggagctcctggacacattaggcccgtactcggagagctcc
ggcaccagcagccccagcacgtcccccagagcctccaaccactcactgcactcgagcggc
tctgcctccaaggccggcatcagccccttcccggaccaggatgacgaggatgaggaaacc
agcatggtgttggttgggaaaatttcattttgtcccaaggacgtcctgggccacggagct
gagggcacaattgtgtatcgaggcatgttcgacaaccgcgacgtagctgtgaagaggatc
ctccccgagtgtttcagcttcgcagaccgcgaggtccagctgctgcgagagtcagacgag
caccccaacgtgatccggtacttctgcacggagagggacaggcagttccagtacatcgcc
atcgagctgtgcgcagccactctgcaggagtatgtggagcagaaggactttgcccacctc
ggcctggagcctatcaccttgctgcagcagaccacctcgggcctggctcaccttcactcc
ctcaacattgttcacagagacctgaaaccccacaacattctcctttccatgcccaacgcg
catggcaggatcaaggccatgatctctgactttggcctctgcaagaagctggcagtgggc
aggcacagcttcagccgccggtctggggtgcctggcacagaaggctggatcgctcctgag
atgctgagcgaagactgcaaggagaaccccacctacacagtggacatcttctctgcaggc
tgtgtcttttactatgtgatatctgaaggcagccacccttttggcaagtccctgcagcgg
caagcaaacatcctcctgggtgcctacagcctcgactgcttacacccagagaagcatgaa
gacgtcattgcgcgtgaattaatagagaaaatgatcgcgatggaccctcagaaacgcccc
tcggcgaagcacgtgctcaaacaccccttcttctggggcctggaaaagcagctccagttc
ttccaggacgtgagtgaccgaattgagaaggagtccctagatggcctgattgttaagcag
ttagagaaaggtggaagagctgtggtgaaaatggactggagggagaatatcaccgtccct
ctccagacagatctgcgtaaattcaggacctacaagggtggctctgtcagggatctcctc
cgagccatgagaaataagaagcaccactaccgggagctgcccacagaggtgcgtgagacg
ctgggctccctcccagatgacttcgtgcgctacttcacatcccgcttcccccacctcctc
ttacacacctaccgggccctggagctgtgtagccacgagagactcttccagccctactac
tgccacgagcccccagagccccagcccctgctgccacccgacgccctctga
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