KEGG   Trichechus manatus latirostris (Florida manatee): 101354431
Entry
101354431         CDS       T05135                                 
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2
  KO
K05853  P-type Ca2+ transporter type 2A [EC:7.2.2.10]
Organism
tmu  Trichechus manatus latirostris (Florida manatee)
Pathway
tmu04020  Calcium signaling pathway
tmu04022  cGMP-PKG signaling pathway
tmu04024  cAMP signaling pathway
tmu04148  Efferocytosis
tmu04260  Cardiac muscle contraction
tmu04261  Adrenergic signaling in cardiomyocytes
tmu04380  Osteoclast differentiation
tmu04919  Thyroid hormone signaling pathway
tmu04972  Pancreatic secretion
tmu05010  Alzheimer disease
tmu05017  Spinocerebellar ataxia
tmu05022  Pathways of neurodegeneration - multiple diseases
tmu05410  Hypertrophic cardiomyopathy
tmu05412  Arrhythmogenic right ventricular cardiomyopathy
tmu05414  Dilated cardiomyopathy
tmu05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:tmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    101354431
   04024 cAMP signaling pathway
    101354431
   04022 cGMP-PKG signaling pathway
    101354431
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    101354431
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    101354431
  09153 Circulatory system
   04260 Cardiac muscle contraction
    101354431
   04261 Adrenergic signaling in cardiomyocytes
    101354431
  09154 Digestive system
   04972 Pancreatic secretion
    101354431
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101354431
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101354431
   05017 Spinocerebellar ataxia
    101354431
   05022 Pathways of neurodegeneration - multiple diseases
    101354431
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    101354431
   05412 Arrhythmogenic right ventricular cardiomyopathy
    101354431
   05414 Dilated cardiomyopathy
    101354431
   05415 Diabetic cardiomyopathy
    101354431
Enzymes [BR:tmu01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.10  P-type Ca2+ transporter
     101354431
SSDB
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Cation_ATPase_N Hydrolase Hydrolase_3 HAD
Other DBs
NCBI-GeneID: 101354431
NCBI-ProteinID: XP_004379145
UniProt: A0A2Y9DRZ8
LinkDB
Position
Unknown
AA seq 1042 aa
MENAHTKTVEEVLSHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDRVEGDSCSLHEFTITGSTYAPIGEVHKDDKPVRCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPITPGV
KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMNLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQEEDVTSKAFTGREFDEL
SPPAQRDACLTARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKDDNPDFDGVDCAVFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNLTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPAARPCSLSACTDGISWPFVL
LVVPLVVWVYSTDTNFTDMFWS
NT seq 3129 nt   +upstreamnt  +downstreamnt
atggagaacgcgcacacaaagacggtggaggaggtgctgagccacttcggcgtcaacgag
agcacggggctgagcctggaacaggtcaagaagctcaaggagagatggggctccaacgag
ttaccggctgaagaaggaaaaaccttgctagaacttgtgattgagcagtttgaagactta
ctagttagaattttattgctggcagcatgtatatcttttgttttggcttggtttgaagaa
ggtgaagaaacaattacagcctttgtagaaccctttgtaattttacttatattagtagcc
aatgcaattgtgggtgtatggcaggaaagaaatgctgaaaatgcaattgaagcccttaag
gagtacgagcctgaaatgggcaaagtgtatagacaggatagaaagagtgtacagcggatt
aaagctaaagacatagttcctggtgatattgtagagattgctgttggtgacaaagttcca
gctgatataagactaacttctatcaaatctacaactctaagagtagaccagtcaattctc
acaggcgaatcggtctctgtcatcaagcacaccgaccccgtccctgacccacgggctgtc
aaccaagataagaagaacatgctgttttctggcacaaacattgcagctggaaaagccatg
ggagtggtggtggcaactggagttaacactgagattggcaagatccgggatgagatggtg
gcaacggagcaggagagaacgcccctccagcagaaactggatgagtttggagaacagctg
tcaaaagtcatctccctcatttgcatcgcagtctggatcataaacattgggcatttcaat
gatcccgttcacggaggctcctggatcagaggtgctatctactactttaaaattgcagtg
gccctggctgttgcagccattcccgaaggtctgcccgctgtcatcaccacctgcctggcc
cttggaacgcgcagaatggcaaagaaaaatgccattgttcgaagccttccctcggtggaa
acccttggttgtacttctgttatctgctcggacaagactggtacacttacaacgaaccag
atgtcggtctgccggatgttcattctggacagagttgaaggagatagttgttctcttcat
gagtttaccataactggctcaacatacgcacctataggagaagtgcataaagatgataaa
ccagtgagatgtcatcaatatgatggtcttgtagaattagcaactatttgtgctctttgt
aatgactctgctttggattacaatgaggcgaagggcgtgtatgaaaaagttggagaagct
acagagactgcactcacatgtctggtagagaagatgaacgtattcgatacggaattgaag
ggtctgtctaaaatagaacgtgcgaacgcctgcaactcggtcattaaacagttgatgaaa
aaagaatttaccctagagttttcacgcgatagaaaatctatgtcggtttattgtacaccg
aacaaaccgagccgaacatcaatgagcaagatgtttgtgaagggcgctcccgagggtgta
attgacaggtgtacccacattcgagttggaagcacaaaggttcccataacccctggggtc
aagcagaagatcatgtctgtcattcgggagtggggcagtggcagcgacaccctgcgctgc
ctggctctggccactcacgacaacccgctgaggagagaagagatgaacctggaggactct
gccaacttcatcaaatacgagaccaatctgaccttcgttggctgtgtgggcatgctggac
cccccgagaattgaggtggcctcgtcagtgaagctgtgcaggcaggcaggcatccgtgtc
atcatgatcacaggggataacaagggcaccgctgtggccatctgtcgccgaatcggcatc
tttgggcaggaagaggatgtgacatcgaaggccttcacaggccgggagtttgacgagctc
agtcccccggcacagagggatgcctgcttgactgcccgctgctttgctcgcgtggagccc
tcccacaagtcgaaaatcgtagagtttcttcagtcttttgatgagattacagctatgaca
ggggacggtgtgaacgatgctcccgctctgaagaagtctgagatcggcatcgccatgggc
tctggcactgccgtggccaagaccgcctccgagatggtcttggccgacgacaacttctcc
accatcgtggctgctgttgaggagggacgggcaatctacaacaacatgaagcagttcatc
cgctacctcatctcgtccaacgtcggcgaggtcgtctgtattttcctgacagcagccctg
ggttttcctgaggctttaattcctgtccagctgctctgggtcaacctggtgacagacggc
ctacccgccaccgccctgggcttcaaccctcctgacctggacatcatggataagccgccc
cggaaccccaaagagccgctgatcagtgggtggctctttttccgttacctcgcgattggc
tgttatgttggtgccgctaccgtgggtgctgctgcatggtggtttatcgctgctgacggc
ggtccacgggtttccttctaccagctgagtcacttcctacagtgtaaagacgacaaccct
gacttcgacggagtggattgtgcagtctttgaatccccatacccgatgacaatggcgctt
tctgttctcgtaaccatagagatgtgtaacgccctcaacagcttgtctgaaaaccagtcc
ttgctgaggatgcccccctgggagaacatctggctcgtgggctctatctgcctgtccatg
tccctccacttcctcatcctctacgtggagcccctgcctcttatcttccagatcacaccg
ctgaacttgacccagtggctgatggtgctgaaaatctccctgcctgtgatcctcatggac
gagaccctcaagttcgtggcccgcaactacctggagcctggtaaagagtgtgtgcagccg
gcggcgcggccgtgctcgctctcggcgtgcaccgacggcatctcctggccctttgtgctg
ctcgttgtgccgctggtggtctgggtctatagcacagacactaacttcaccgacatgttc
tggtcttga

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