Trichechus manatus latirostris (Florida manatee): 101354872
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Entry
101354872 CDS
T05135
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
tmu
Trichechus manatus latirostris (Florida manatee)
Pathway
tmu00230
Purine metabolism
tmu00670
One carbon pool by folate
tmu01100
Metabolic pathways
tmu01523
Antifolate resistance
Module
tmu_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
tmu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
101354872
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
101354872
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101354872
Enzymes [BR:
tmu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
101354872
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
101354872
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
101354872
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
GARS_N
AIRS_C
GARS_C
AIRS
ATP-grasp
ATP-grasp_2
CPSase_L_D2
ATP-grasp_4
ATP-grasp_3
Dala_Dala_lig_C
Sacchrp_dh_NADP
RimK
ATP-grasp_5
Motif
Other DBs
NCBI-GeneID:
101354872
NCBI-ProteinID:
XP_004387030
UniProt:
A0A2Y9E4G0
LinkDB
All DBs
Position
Unknown
AA seq
1010 aa
AA seq
DB search
MAARVLVIGSGGREHTLAWKLAQSPHVKQVLVAPGNAGTACSEKISNAAVSVSNHAALAQ
FCKDEKIEFVVVGPEAPLAAGIVGNLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TAKWRAFTKPEEACSFIMSADFPALVVKASGLAAGKGVIVAKSKEEACRAVQDIMQDKAF
GAAGETIVVEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDVGPNTGGMGAYCPTP
QVSRDLLLRINNTILQRTVDGMQQEGTPYTGVLYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCTALPTWLEHGTAITVVMASKGYPGDYTKGVEITGFPEA
QALGLEVFHAGTALKDGRVVTNGGRVLTVTAIREDLPSALEEAKKGLAAIKFEGAVYRKD
IGRRALAFLQQPRGLTYKEAGVDIAAGDMLVKKIKPLARATSRPGCEVDLGGFAGLFDLK
AASFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLNLDTAEAVVAGIAEACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAVERDQKLP
HMDRIMEGDAVIGVASSGLHSNGFSLVRKIVEKSCLSYSSPAPEGCGDQTLGQLLLTPTR
IYSQTLLPVLRSGHVKAFAHITGGGLLENIPRVLPQGLGVDLDAWAWGIPRIFSWLQQEG
HLAEEEMARTFNCGIGAALVVPRDLTEQILRDIQQHKEEAWVIGSVVACPADSPRVKVRN
LMESMQINRSVLENSSLENHVSVQPPRARVAVLISGTGSNLQALIDSTREPHSSARVVVV
ISNKAAVAGLDKAETAGIPTRVINHKLYKSRVEFDNAVDQVLEEFSTDIVCLAGFMRILS
GPFVRKWNGRMLNIHPSLLPSFKGANAHEQALEAGVAVTGCTVHFVAEDVDAGQIILQEA
VPVKRGDSVATLSERVKTAEHKIFPAALQLVASGAVQLGENGKICWVKKE
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtgcttgtaattggcagtggaggaagggagcacactctggcctggaaa
cttgcgcagtctcctcatgtcaaacaagtgctggtcgccccaggaaacgcaggcactgct
tgctccgaaaagatttcaaatgccgccgtctcagtcagcaatcacgctgccctcgctcag
ttctgcaaagatgagaaaatagaattcgtggtggttggaccggaggcgcctctggctgct
ggaattgttggtaacctcacatctgcgggcgtgcgatgctttggccccacagcagaagca
gctcaactggagtccagcaaaaggtttgccaaagagtttatggatcgacatggaatccca
actgcaaagtggagagctttcaccaaacctgaagaagcctgcagcttcatcatgagcgcc
gacttccctgccttggtcgtgaaggccagtggtcttgccgccgggaaaggagtgattgtt
gccaagagcaaagaagaggcctgcagagctgtgcaggacatcatgcaggacaaagctttt
ggagcagctggagaaacaattgtcgttgaagagcttcttgaaggagaagaggtgtcttgt
ctgtgtttcactgatggaagaactgtggccccgatgcccccagcacaggaccataagcga
ttgctggaaggagatgtcggccccaacacagggggcatgggagcctattgtccgacacct
caggtttccagggatttgttactgagaattaacaataccattcttcagaggacagtggat
ggcatgcagcaggagggtacgccatacacaggtgttttgtacgctggtataatgctgacc
aaggacggccccaaagttctggagtttaattgtcgttttggtgacccagagtgccaagta
atcctcccacttcttaaaagcgacctttatgaggtgatccagtccaccttggatggcctg
ctctgcacagctctgcccacttggctggaacacggcaccgccatcactgtcgtcatggca
agtaaaggttatcctggagactacaccaagggtgtggagatcacagggtttcctgaggct
caggcgttagggctggaggtgttccatgcaggcactgccctgaaggacggtagagtggtg
actaacgggggtagagtcctcacagtaaccgccatccgggaagatctcccgtcagcgctt
gaagaggccaagaagggactggctgctataaagtttgagggagccgtttacaggaaggac
attggccgtcgtgccctagccttcctccagcagcccaggggtctgacttacaaggaagct
ggggtagatattgcagctggagatatgctggtcaagaaaattaagcctttagcaagagcc
acctccagaccaggctgtgaggttgatcttggaggttttgctggcctttttgatttgaaa
gcagccagtttcaaagatcctcttctggcctctggaacagatggcgttggaactaaactg
aagattgcccagctgtgcaataaacatgatactattggtcaagatctggtcgccatgtgt
gtaaatgatattctggcacaaggggcagagcctctcttcttcctggactacttttcctgt
ggaaaactcaaccttgatacagcagaagctgttgtcgctgggatcgcggaagcttgtgga
aaagctggatgtgctctccttggaggtgaaacagctgaaatgcctgacatgtaccctccc
ggagagtatgacctggccggatttgccgtcggtgccgtggagcgggatcagaaacttcct
cacatggacagaatcatggagggggatgcggttattggagtagcttcatctggcctccat
agcaatgggtttagcctcgtgaggaagattgtggagaaatcttgcctctcgtactcctcc
ccagcacctgagggctgtggtgaccaaacgctagggcagttacttctaactccaactaga
atctacagccagacactgttacccgtcctacgttcaggacacgtcaaggcttttgcgcat
atcactggaggagggttgctagaaaacatccccagagtccttcctcagggacttggggtg
gacctagatgcttgggcctgggggatccccaggatcttctcgtggttgcagcaggaaggg
caccttgctgaagaagagatggccagaacgtttaactgtgggattggggctgccctcgtg
gtccccagggatctgacggagcagattctgagggatattcagcagcacaaggaagaagcc
tgggtgattggcagtgtggttgcatgtcctgcggattccccgcgtgtgaaagtcaggaat
ctgatggaaagcatgcagataaacaggtcagtgttggagaacagctccctggaaaatcac
gtctctgtccaaccaccaagggcacgagtggctgtcctgatatctggaacaggctcgaac
ctccaagcactgattgacagtactcgggagccacacagctctgcacgcgttgttgttgtc
atctccaacaaagccgcagtggctggactggacaaagcagagacagctggtattcccacc
agagtaataaaccataaattatataaaagtcgtgtagaatttgacaatgcagtcgaccaa
gtccttgaagagttctccacagacatagtgtgtctcgcaggattcatgagaattttatct
ggcccttttgtcaggaaatggaatgggcgaatgctcaacatccacccgtccttgctgcct
tcttttaagggggcgaacgcccacgagcaagccctggaggccggtgtcgccgtcactggc
tgcactgtccacttcgtagccgaagacgtagatgcgggacaaattattttacaagaagct
gttccggtgaagaggggtgactccgtggcgactctgtctgaaagggtgaagacagcagaa
cataagatattccctgcggccctccagctggtggccagcggggcagtccagcttggagaa
aacggcaagatctgttgggtcaaaaaggagtga
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