Trichechus manatus latirostris (Florida manatee): 101356953
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Entry
101356953 CDS
T05135
Name
(RefSeq) nitric oxide synthase, endothelial isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
tmu
Trichechus manatus latirostris (Florida manatee)
Pathway
tmu00220
Arginine biosynthesis
tmu00330
Arginine and proline metabolism
tmu01100
Metabolic pathways
tmu04020
Calcium signaling pathway
tmu04022
cGMP-PKG signaling pathway
tmu04066
HIF-1 signaling pathway
tmu04071
Sphingolipid signaling pathway
tmu04151
PI3K-Akt signaling pathway
tmu04370
VEGF signaling pathway
tmu04371
Apelin signaling pathway
tmu04611
Platelet activation
tmu04915
Estrogen signaling pathway
tmu04921
Oxytocin signaling pathway
tmu04926
Relaxin signaling pathway
tmu04931
Insulin resistance
tmu04933
AGE-RAGE signaling pathway in diabetic complications
tmu05415
Diabetic cardiomyopathy
tmu05417
Lipid and atherosclerosis
tmu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
tmu00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
101356953
00330 Arginine and proline metabolism
101356953
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
101356953
04371 Apelin signaling pathway
101356953
04066 HIF-1 signaling pathway
101356953
04020 Calcium signaling pathway
101356953
04071 Sphingolipid signaling pathway
101356953
04022 cGMP-PKG signaling pathway
101356953
04151 PI3K-Akt signaling pathway
101356953
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101356953
09152 Endocrine system
04915 Estrogen signaling pathway
101356953
04921 Oxytocin signaling pathway
101356953
04926 Relaxin signaling pathway
101356953
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101356953
05418 Fluid shear stress and atherosclerosis
101356953
05415 Diabetic cardiomyopathy
101356953
09167 Endocrine and metabolic disease
04931 Insulin resistance
101356953
04933 AGE-RAGE signaling pathway in diabetic complications
101356953
Enzymes [BR:
tmu01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
101356953
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
101356953
NCBI-ProteinID:
XP_004372791
UniProt:
A0A2Y9DDV9
LinkDB
All DBs
Position
Unknown
AA seq
1208 aa
AA seq
DB search
MGNLKSVGQEPRPPCGLGLGLGLGLCSKQGPASPASEPSRAPAPVPPPAPDHSRPPLAPN
SPLPARPPEGPKFPRVKNWEVGTITYDTLSAQAQQDGPCTPRHCLGSLVFPRKLQSQTSR
GPAPPERLLKQARDFIHQYYSSIKRSGSQAHEQRLQEVEAEVVATGTYQLRESELVFGAK
QAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYGTNRGNLRSAITVFPQRV
PGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQA
PDEPPEVFPLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFTAAPFSG
WYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKV
TIVDHHAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFHY
QPDPWKGSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYA
QQLGRLFRKAFDPRVLCMDEYDVVSLEHETLVVVVTSTFGNGDPPENGESFAAALMEMTS
PYNSSPRPEQHKSYKMRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSR
AYPHFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGED
AKAAARDIFSPKRSWKRQRYRLSPQAKGLQLLPGLIHVHRRKMFQATVLSVENLQSSKST
RATILVRLDIGGQQGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPPPTEPIAVEQLEKG
SPGGPPPGWVRDPRLPPCTLRQALTYFLDITSPPSPQLLRLLSTLAEEPSEQQELETLSQ
DPRRYEEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSASPGEIHL
TVAVLAYRTQDGLGPLHYGVCSTWLSQLKVGDPVPCFIRGAPSFRLPPDPSLPCILVGPG
TGIAPFRGFWQERLHDIESKGLQPAPMTLVFGCRCSQLDHLYREEVQDAQQRGVFDRVLT
AFSREPDSPKTYVQDLLRTELAAEVHRVLCLERGHMFVCGDVTMATSVLQTVQRILAAEG
DMELDEAGDFIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWAFDP
PGANTPGP
NT seq
3627 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagtgtgggccaggagcctaggcctccctgcgggctggggctgggg
ctgggcctcgggctatgcagcaagcagggcccagcctccccagcctcggagcccagccgg
gcaccagcaccagtgcccccacctgcgcccgaccacagccgccctcccctggctcccaac
agccccctaccagcccggcccccagaaggacccaagttccctcgtgtgaagaactgggaa
gtggggaccatcacctatgataccctgagtgcccaggcacagcaggacggaccctgcacc
ccaagacactgcctgggctcccttgtatttccacggaaactacagagccagacatcccgg
ggccctgcaccccctgagaggcttctgaaacaggcccgggacttcatccaccagtactac
agctccatcaagaggagcggctcccaggcccatgagcagcgtcttcaggaggtagaagcc
gaggtggtggccacaggcacctaccagcttcgggagagcgagctggtgttcggggctaag
caggcctggcgcaatgctccccgatgcgtcggccgcatccagtgggggaagctgcaggta
tttgatgcccgggactgcagctctgcgcaggagatgttcacctacatctgcaaccacatc
aagtatggcaccaataggggtaaccttcgctctgccatcaccgtgttcccccaacgtgtc
cctggccgcggtgatttccggatctggaacagccagctggtgcgttatgctggctacagg
cagcaggatggctccgtgcgtggggaccctgccaacgtggagatcactgagctctgcatc
cagcacggctggaccccaggaaatggccgatttgatgtgctgcccctgctgctccaggcc
ccagatgagcccccggaggtcttccctttgccccctgaactggtccttgaggtgcccctg
gagcaccccacgctggagtggtttgcagccctgggcctgcgttggtatgccctcccagcg
gtgtccaacatgctgctggaaatcgggggcctggagttcactgcggctcctttcagcggc
tggtacatgagcactgagattggcactcggaacctgtgtgatccccaccgctacaacatt
ctagaggatgtggccgtctgcatggacctagacacacggaccacctcgtccctgtggaaa
gacaaggcagctgtggaaattaacttggctgtgctgcacagttaccagctggccaaagtg
accattgtggaccaccacgctgccacagcctccttcatgaagcacctggagaatgagcag
aaggcgaggggagggtgccctgccgactgggcctggatcgtgccccccatctctggcagc
ctcacacctgtcttccatcaagagatggtcaactatttcctgtcccccgccttccactac
cagccagatccctggaagggaagtgcagccaagggcacaggtatcaccaggaagaagacc
tttaaggaagtggccaatgcagtcaagatctctgcctcgctcatgggcactgtgatggca
aagcgagtgaaggcgacaatcctgtatggctctgagactggccgggcccagagctacgca
cagcagctggggaggctcttccggaaggctttcgatccccgggtcctgtgcatggatgag
tatgatgtggtgtcccttgagcacgagacactggtggttgtggtgaccagcacatttggg
aacggtgatccacccgagaacggcgagagctttgcagccgccctgatggaaatgaccagc
ccctacaacagctcccctcgacccgaacagcacaagagctacaaaatgcgcttcaacagt
gtctcttgctcagaccccctggtctcctcctggcggcggaaaaggaaggagtctagtaac
acagacagtgcgggggcgctgggcaccctcaggttctgtgtgttcgggctgggctcccgg
gcatatccccacttctgcgccttcgcgcgcgcagtggacacgcggctggaggagctgggc
ggagagcggctgctgcagctgggccagggggatgagctgtgcggccaggaggaagccttc
cgtggctgggcccaggccgccttccaggccgcctgtgagactttctgtgtgggagaagac
gccaaggctgctgcccgggatatattcagtcccaaacggagctggaagcgccagagatac
cggctgagtccccaggccaagggcctccagctgctgccaggcctgatccacgtgcacagg
cggaaaatgttccaagctactgtcctctcagtggaaaacctgcaaagcagcaagtccacc
cgggccaccatcctggtgcgcctagacattggagggcagcaggggctgcagtatcagcca
ggggaccacattggggtctgcccgcccaaccggcctggcctggtggaggcgctgctgagc
cgcgtggaagacccgccgccgcccaccgagcccattgcagtggagcagctggagaagggc
agccctggtggcccgccccccggctgggtacgggaccccaggctgcccccatgcacactg
cgccaggctctgacctacttcctggacatcacatccccacccagccctcaactccttcga
ctgctcagcaccctcgctgaagagcccagtgaacagcaggagctggaaaccctcagccag
gacccccggcgctacgaggagtggaagtggttccgttgccccacgcttctggaagtgctg
gagcagtttccgtcggtagcactgccggcccccctgctcctcacccagctgcctctgctc
cagccacggtactactccgtcagctcagcacccagtgcctccccaggagagatccacctc
acagtagctgtgctggcataccggacccaggatggcctgggcccactgcactatggtgtc
tgctccacgtggctgagccagctcaaggttggagaccctgtgccctgcttcatcagaggt
gctccctccttccggctgccgcctgatcccagcttgccctgcatcctcgtgggacctggc
acgggcattgcccccttccggggattctggcaggagaggctgcacgacattgaaagcaaa
gggctgcagcccgcccccatgaccttggtgtttggctgccgatgctcccagctcgaccac
ctctaccgtgaggaggtgcaagacgcccagcagcgcggggtgtttgaccgtgttctcacc
gccttctcccgggaacccgacagccccaagacttacgtgcaggacctcctgcggactgag
ctggctgctgaggtgcaccgcgtgctgtgcctcgagcggggccacatgttcgtctgtggc
gatgtcaccatggcgaccagcgtcctgcaaaccgtgcagcgcatcctagcggcagagggc
gacatggagctggacgaggccggagacttcatcggcgtgctgcgggatcagcaacgctac
cacgaggacattttcgggctcaccctgcgcacccaggaggtgacaagccgcatacgcacc
cagagcttttccctacaggagcggcagctgcggggtgcagtgccctgggcgttcgacccg
cccggtgcaaacacccctggcccctga
DBGET
integrated database retrieval system
