Trichechus manatus latirostris (Florida manatee): 101357085
Help
Entry
101357085 CDS
T05135
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
KO
K04851
voltage-dependent calcium channel L type alpha-1D
Organism
tmu
Trichechus manatus latirostris (Florida manatee)
Pathway
tmu04010
MAPK signaling pathway
tmu04020
Calcium signaling pathway
tmu04022
cGMP-PKG signaling pathway
tmu04024
cAMP signaling pathway
tmu04218
Cellular senescence
tmu04260
Cardiac muscle contraction
tmu04261
Adrenergic signaling in cardiomyocytes
tmu04270
Vascular smooth muscle contraction
tmu04530
Tight junction
tmu04713
Circadian entrainment
tmu04723
Retrograde endocannabinoid signaling
tmu04724
Glutamatergic synapse
tmu04725
Cholinergic synapse
tmu04726
Serotonergic synapse
tmu04727
GABAergic synapse
tmu04728
Dopaminergic synapse
tmu04911
Insulin secretion
tmu04912
GnRH signaling pathway
tmu04921
Oxytocin signaling pathway
tmu04924
Renin secretion
tmu04925
Aldosterone synthesis and secretion
tmu04927
Cortisol synthesis and secretion
tmu04929
GnRH secretion
tmu04930
Type II diabetes mellitus
tmu04934
Cushing syndrome
tmu04935
Growth hormone synthesis, secretion and action
tmu04973
Carbohydrate digestion and absorption
tmu05010
Alzheimer disease
tmu05020
Prion disease
tmu05022
Pathways of neurodegeneration - multiple diseases
tmu05031
Amphetamine addiction
tmu05207
Chemical carcinogenesis - receptor activation
tmu05410
Hypertrophic cardiomyopathy
tmu05412
Arrhythmogenic right ventricular cardiomyopathy
tmu05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
tmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101357085
04020 Calcium signaling pathway
101357085
04024 cAMP signaling pathway
101357085
04022 cGMP-PKG signaling pathway
101357085
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
101357085
09144 Cellular community - eukaryotes
04530 Tight junction
101357085
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
101357085
04929 GnRH secretion
101357085
04912 GnRH signaling pathway
101357085
04921 Oxytocin signaling pathway
101357085
04935 Growth hormone synthesis, secretion and action
101357085
04924 Renin secretion
101357085
04925 Aldosterone synthesis and secretion
101357085
04927 Cortisol synthesis and secretion
101357085
09153 Circulatory system
04260 Cardiac muscle contraction
101357085
04261 Adrenergic signaling in cardiomyocytes
101357085
04270 Vascular smooth muscle contraction
101357085
09154 Digestive system
04973 Carbohydrate digestion and absorption
101357085
09156 Nervous system
04724 Glutamatergic synapse
101357085
04727 GABAergic synapse
101357085
04725 Cholinergic synapse
101357085
04728 Dopaminergic synapse
101357085
04726 Serotonergic synapse
101357085
04723 Retrograde endocannabinoid signaling
101357085
09159 Environmental adaptation
04713 Circadian entrainment
101357085
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
101357085
09164 Neurodegenerative disease
05010 Alzheimer disease
101357085
05020 Prion disease
101357085
05022 Pathways of neurodegeneration - multiple diseases
101357085
09165 Substance dependence
05031 Amphetamine addiction
101357085
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
101357085
05412 Arrhythmogenic right ventricular cardiomyopathy
101357085
05414 Dilated cardiomyopathy
101357085
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
101357085
04934 Cushing syndrome
101357085
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
tmu04040
]
101357085
Ion channels [BR:
tmu04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
101357085
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
CAC1F_C
GPHH
PKD_channel
Motif
Other DBs
NCBI-GeneID:
101357085
NCBI-ProteinID:
XP_004368677
UniProt:
A0A2Y9D6K0
LinkDB
All DBs
Position
Unknown
AA seq
2179 aa
AA seq
DB search
MMMMMMMKKMQHQRQQADHANEANYARGTRLPLSGEGPTSQPNSSKQTVLSWQAAIDAAR
QAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACIS
IVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKII
AYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEAGNHSSGKSGGFDVKALRA
FRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKTC
FFADSDIVAEEDPAPCAFSGNGRQCTANDTECRSGWVGPNGGITNFDNFAFAMLTVFQCI
TMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARGD
FQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGKRNTSMPTSETESVNTENVSG
EGENQGCCGSLWCWWKRRGAAKAGPSGCRRWGQAISKSKLSRRWRRWNRFNRRRCRAAVK
SVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQA
YFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVA
SLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETLTKRSTFDNFPQALLTVFQI
LTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESL
NTAQKEEAEEKERKKIARKESLENKKNNKPEVNQIANSDNKVTIDDYREEDEDKDPYPPC
DVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIIPIPEGSAFFILSKTNPIRVGCHK
LINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTTF
GAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGL
KHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFIL
YKDGEVDNPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENIGPI
YNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALK
ARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILN
MVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADPTESENIPVPT
AAPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLF
FIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLC
DPESDYNPGEEYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHH
LDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSD
GTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEV
TVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTVALQAGLRTLHDIGPEIRRAISCD
LQDDEPEETKLEEEEDLFKRNGALLGNHVNHVNSDRRDSLQQTNTAHRPLHVQRPSIPPA
SDTEKPLFPPAGNSVCHNHHNRNSIGKPIPNSTNANLNNANMSKAAHGKRPSIGNLEHVS
ENGHHSSHKHDREPQRKSSIKRTRYYETYVRSDSGDEQLPAICREDPEIYSYFRDPRCLG
EQEYFSGEECYEDDSSPTGSWHNYGYYSRSPGSSWDFERPRGYHHPQGFLEDADSPTCHD
SRRSPRRRLLPPTPTPHRRSSFNFECLRRQGSQEEVPLSPAFPHRTALPLHLMQQQIMAV
AGLDSSKAQYSPSHSTRSWATPPATPPYQDWTPCYTPLIQVERSESLDQVNGSLPSLHRS
SWYTDEPDIAYRTFTPASLTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYARDPKFVS
ATKHEIADACDLTIDEMESAASHLLNGNMSPRANGDVGPISHQQDYELQDFGPGYSDEEP
DPGRYEEDLADEMICITTL
NT seq
6540 nt
NT seq
+upstream
nt +downstream
nt
atgatgatgatgatgatgatgaaaaaaatgcagcatcaacggcagcaagcggaccacgcg
aacgaggcaaactatgcaagaggcaccagactccctctttctggtgaaggaccaacttct
cagccgaatagctccaagcagactgtcctgtcttggcaagctgcaatcgacgctgctaga
caggccaaggctgcccaaactatgagcacctctgcgcccccacctgtaggatctctctcc
caaagaaaacgtcagcaatacgccaagagcaaaaaacagggtaactcatccaacagccga
cctgcccgtgcccttttctgtttatcactcaataaccccatccgaagagcctgcattagt
atagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgtgtg
gccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataacttg
gaaaaagtagaatatgccttcctgattatttttacagtcgagacatttttgaagattata
gcgtatggattattactacatcctaatgcttatgttaggaatggatggaatttattggat
tttgttatagtaatagtaggattgtttagtgtaattttggaacaattaaccaaagaaaca
gaagccggtaaccactctagtggcaaatcaggaggctttgatgtcaaagccctccgcgcc
tttcgagtgttacgaccccttcgactagtatcaggcgtacccagtttgcaggttgtcctg
aactccattataaaagccatggttcccctcctgcacatagcccttttggtattatttgta
atcataatctatgctattataggattggaactttttattggaaaaatgcacaaaacatgc
ttttttgctgactcagatatcgtagctgaagaggacccagcaccatgtgcgttctcaggg
aatggacgccagtgtaccgccaatgacacagagtgtaggagtggctgggttggcccaaat
ggaggcatcaccaactttgataactttgcctttgccatgctcactgtgtttcagtgtatc
accatggaaggctggacagacgtgctctactgggtaaatgatgcgataggatgggaatgg
ccatgggtatattttgttagtctgatcatccttggctcatttttcgtccttaacctggtt
cttggtgtccttagtggagaattttcaaaggaaagagagaaggctaaagcacggggagat
ttccagaagctccgagagaagcagcagctggaagaggatctaaagggctacttggattgg
attacccaagcagaagatattgatcctgagaatgaggaagaaggaggagaagaaggcaaa
cgaaatactagcatgcccaccagcgagactgagtctgtgaacacagaaaatgtaagtggt
gaaggcgagaaccaaggctgctgtggaagtctgtggtgctggtggaagagaagaggtgcg
gccaaggctgggccctcagggtgtcggcggtggggtcaagccatttcaaaatccaaactc
agccgacgctggcgtcgctggaaccgattcaatcgaagaagatgtagggctgctgtgaag
tctgtcacgttttactggctggttattgtcctggtgtttctcaataccttaaccatttcc
tctgagcactacaaccagcctgactggttgacgcagattcaagatatcgctaacaaagtc
ctcttggctctgttcacctgtgagatgctggtaaaaatgtacagcttgggtctgcaggca
tatttcgtctctcttttcaatcggtttgattgcttcgtggtgtgtggtggaattactgaa
acgatcttagtggaactggaaatcatgtctcccctgggaatctctgtgtttcggtgtgtg
cgcctcttaagaattttcaaagtgaccaggcactggacttccctcagcaacttggtggca
tccttgttaaactccatgaagtccatcgcttcactgctacttctgctctttctcttcatc
atcatcttttccttacttgggatgcagctgtttggcggcaagtttaattttgatgaaacg
ctaaccaagcggagcacctttgacaatttccctcaagcgcttttgacagttttccagatt
ctgacaggtgaagactggaatgctgtgatgtacgatggcattatggcttacgggggcccg
tcctcttcaggaatgatcgtctgcatctacttcatcatcctcttcatttgtggtaactat
attctactgaatgtcttcttggccatcgctgtagacaatttggctgatgctgaaagtttg
aacactgctcagaaagaggaagctgaagaaaaagaaaggaaaaagattgccagaaaagag
agcctggaaaataaaaagaacaacaaaccagaagtcaaccagatagccaacagtgacaac
aaggttacaattgatgactaccgagaagaggatgaggacaaggacccctacccaccttgt
gatgtgccagtaggggaagaggaagaggaggaggaagaggatgaacctgaggtccctgct
ggtccccgtcctcgcagaatctcagagttgaacatgaaagagaaaatcatccccatccct
gaaggaagcgctttcttcattcttagcaagaccaacccgatccgcgtcggctgccacaag
ctcatcaaccaccacatcttcactaacctcatcctcgtcttcatcatgctgagcagcgct
gccctcgccgctgaggaccccatccgcagccactccttccggaacactatactgggttac
tttgactatgctttcacagccatcttcactgttgaaatcctgttaaagatgacgactttt
ggagctttcctccacaaaggggctttctgcaggaactacttcaatttactggatatgctg
gttgttggggtgtctctggtgtcgtttgggattcaatccagtgctatctccgttgtgaag
attctgagagtgttaagggtcctgaggcccctcagggcaatcaacagagcaaaaggactt
aagcacgttgtccagtgtgtctttgtggccatccggacaatcggcaacatcatgatcgtc
accacccttcttcagttcatgtttgcctgcattggggtccagttgttcaagggaaaattc
tatcgctgcacagatgaagccaaaagtaatcctgaagaatgcagggggcttttcattctc
tacaaggacggggaggttgataaccccgtggtgcgtgagaggatctggcaaaacagtgat
ttcaactttgacaacgtcttgtctgctatgatggcacttttcacagtctccacgtttgag
ggctggcctgcgttgctgtataaagctattgattcaaatggcgagaacatcggcccgatc
tacaactaccgcgtggagatctccatcttcttcatcatctacatcatcattgtggctttc
ttcatgatgaacatctttgtgggttttgtcatcgttacatttcaggagcagggagaaaaa
gagtataagaactgtgagctggacaaaaatcagcgtcagtgtgttgaatatgccttgaaa
gcccgacctttgcggagatacatccccaaaaacccctaccagtacaagttctggtatgtg
gtgaactcctcgccttttgaatacatgatgtttgtcctcatcatgctcaacacactctgc
ttggccatgcagcactatgagcagtctaagatgtttaatgacgccatggacattctgaac
atggtcttcaccggggtgttcaccgttgagatggttttgaaagtcattgcatttaaacct
aaggggtattttagtgatgcctggaacacgtttgactccctcatcgtaatcggcagcatt
atagacgtggccctcagcgaagcggacccaactgaaagtgaaaatatccctgtcccaact
gctgcacctgggaactctgaagagagcaatagaatctccatcacctttttccgtcttttc
cgagtgatgcgattggtgaagcttctcagcaggggtgaaggcatccggacgttgctgtgg
acttttattaagtcctttcaggccctcccgtatgtcgcccttctcatagccatgctgttc
ttcatctatgcggttattggcatgcagatgtttgggaaagttgccatgagagataacaac
cagatcaatagaaataataacttccaaacctttccacaggcggtgctcctgctcttcagg
tgtgccaccggggaggcctggcaggaaatcatgctagcctgcctccccgggaagctctgt
gacccagagtcggactataaccccggggaggagtacacgtgcgggagcaattttgcgatt
gtttatttcatcagtttttacatgctctgtgcgtttctgatcatcaatctgtttgtggcc
gtcatcatggacaactttgattatctgacccgggactggtctattctggggcctcaccat
ttagatgaattcaaacgaatatggtcagaatatgaccctgaggcaaagggacggataaaa
cacctggacgtggtcactctgctcaggcgcatccagccacccctggggtttgggaaatta
tgcccacacagagtagcatgcaagagattagttgccatgaacatgcctctcaacagtgat
ggcacagtcatgtttaatgcaactctgtttgccttggttcgaactgctcttaaaatcaag
actgaaggaaacctggaacaagctaatgaagaactccgagctgtgataaagaaaatctgg
aagaaaaccagcatgaaactacttgaccaagttgtccctccagctggtgatgatgaggta
accgtggggaagttctatgccactttcctgatacaggactactttaggaaattcaagaaa
cggaaggaacaaggactggtgggaaaatacccagcgaagaacaccacagttgccctacag
gcgggattaaggacccttcacgacattgggccagaaatccggcgggctatatcctgtgat
ctgcaagatgatgaaccagaggaaacaaaactagaagaagaagaagatttgttcaaaaga
aatggtgccctgcttggaaaccatgtcaatcatgttaatagtgataggagagattccctt
cagcagaccaataccgcccaccgtcccctgcatgtccaaaggccttcaattccacctgca
agtgatactgagaaaccgctgtttcctccagcaggaaattcggtgtgtcataaccatcat
aaccgtaattccataggaaaaccaattcccaactcaacaaatgccaatctcaataatgcc
aatatgtccaaagctgcccatggaaagcggcccagcattgggaaccttgagcatgtgtct
gaaaatgggcatcattcctctcacaagcatgaccgtgagcctcaaagaaagtccagtatt
aaaagaacccgctattatgagacttatgttaggtctgactctggagatgaacagctccca
gctatttgccgggaagatccagagatatacagctacttcagggacccccgctgcttgggg
gagcaggagtatttcagtggtgaggagtgctacgaggatgacagctcgccgaccgggagc
tggcataactatggctactacagcagatccccaggcagcagctgggacttcgaaaggccc
cgaggctaccatcacccccagggcttcttagaggacgccgactcacccacttgccacgac
tctcggagatctccaaggagacgcctactacctccaaccccaacaccccaccggagatcc
tccttcaactttgagtgcctgcgcaggcagggcagccaggaggaggtcccgctgtcgccc
gccttcccccaccgcacggccctgcctctgcacctcatgcagcaacagatcatggcagtt
gccggcctagattccagtaaagcccagtactcaccgagtcactcgacccggtcatgggcc
acccctccagcgacccctccctaccaggactggacaccctgctacacccccctgatccag
gtagagcggtcagagtccctggaccaggtcaacggcagcctgccatccctgcaccgaagc
tcctggtacacggatgaacccgatatcgcctatcggactttcacgccagccagcctgact
gtccccagcagcttccggaacaaaaacagcgacaagcagaggagtgcagacagcttggtg
gaggcagtcctcatatccgaaggcttgggacggtatgcgagggacccaaaatttgtgtca
gcaacaaaacatgagatcgccgatgcctgtgacctaaccatcgacgagatggagagtgca
gccagccacctgctcaacgggaacatgagtccccgagccaatggggacgtgggccccatc
tcacaccagcaggactatgagctacaagacttcggtcctggctacagtgacgaagagcca
gaccctgggagatatgaggaggacctggcagatgaaatgatatgcatcaccaccttgtag
DBGET
integrated database retrieval system
