Trichechus manatus latirostris (Florida manatee): 101358230
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Entry
101358230 CDS
T05135
Name
(RefSeq) DNA topoisomerase 2-beta isoform X2
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
tmu
Trichechus manatus latirostris (Florida manatee)
Pathway
tmu01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
tmu00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
101358230
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
tmu03032
]
101358230
03036 Chromosome and associated proteins [BR:
tmu03036
]
101358230
Enzymes [BR:
tmu01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
101358230
DNA replication proteins [BR:
tmu03032
]
Eukaryotic type
DNA Topoisomerases
101358230
Chromosome and associated proteins [BR:
tmu03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
101358230
Centrosome formation proteins
Centriole proteins
101358230
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
101358230
NCBI-ProteinID:
XP_004377432
UniProt:
A0A2Y9DML2
LinkDB
All DBs
Position
Unknown
AA seq
1618 aa
AA seq
DB search
MAKSGGGAGAGAGGGNGALTWVNNAARKEESETANRNDSSKKLSVERVYQKKTQLEHILL
RPDTYIGSVEPSTQLMWVYDDDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCI
KVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDERKVTGGRNGY
GAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLSK
FKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVA
LKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKN
KAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNC
GIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSA
KSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDA
ESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQ
ELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPED
DAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELIL
FSNSDNERSIPSLVDGFKPGQRKVLYTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALM
MTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPAMDDNL
LKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLEGLDP
HPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLN
GTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDH
MGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESSKLNNQARFILEKIQGKITI
ENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEETQNQQDDSSSDSGTPAGPDFNYI
LNMSLWSLTKEKVEELIKQRDAKGRELCDVKRKSPSDLWKEDLAAFVEELDKVEAQERED
ILAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRVVPEITAMKADASKKLLKKKKGDLD
TTIVKVEFDEEFSGTVEGTGEEALTPSAPINKGPKPKREKKEPGTRVRRTPASSGKSNTK
KVKKRNPWSDDESKSESDLEETEAVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDD
DNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKPKATPEKPSHDKKSQDFGNL
FSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKPTDKVPSKTVAAKKGKPSSDITPKP
KRTPKQKKVEAVNSDSDSEFGVPKKTAASKGKGRGAKKRKASGSENEGDYNPGRKTSKTT
TSKKPKKSSFDQDSDVDIFPSDFASEPPSLPRTGRARKEVKYFAESDEEEDVDFAMFN
NT seq
4857 nt
NT seq
+upstream
nt +downstream
nt
atggccaagtcgggtggcggcgcaggagcgggcgcaggcggcggcaacggggcgctgacc
tgggtgaacaatgctgcaagaaaagaagagtcagaaactgcaaacagaaatgattcttca
aagaagttgtctgttgagagagtgtatcagaagaagacgcaacttgaacacattctcctt
cgtcctgatacatacattgggtcagtggagccatcgacacagctgatgtgggtgtatgat
gatgatgtaggaatgaattgcagagaggttacctttgtgccaggtttatacaagatcttt
gatgaaattttggttaatgcagctgacaataaacagagggataagaacatgacctgcatt
aaagtttctattgatcctgaatctaacattataagcatttggaataatggaaaaggcatt
ccagtagtagaacataaagtagagaaagtatatgttcctgctttaatttttggacaactt
ttaacatccagtaattacgacgatgatgagagaaaagttacaggtggtcgcaatggttac
ggtgcaaaactttgtaatattttcagtacaaagtttacagtagaaacggcgtgcaaggaa
tacaaacatagttttaaacagacatggatgaataatatgatgaagacttctgaagccaaa
attaaacattttgatggtgaagattacacatgcataacattccagccagatctgtccaaa
tttaagatggaaaaacttgacaaggatatcgtggccctcatgaccagaagagcctatgac
ttggcaggctcctgcaaaggggtcaaagtcatgtttaatggaaagaaattgcctgtaaat
ggatttcgaagttatgtagatctttatgtaaaagacaaattggatgaaactggggtggcc
ctgaaggttattcatgaacttgcgaatgaaagatgggatgtttgtctcactttgagcgaa
aaaggattccagcaaattagctttgtaaatagtattgcaactacaaaaggtggacgacac
gttgattatgtagtagatcaagttgttggtaaactgattgaagtagttaagaaaaagaac
aaagctggggtatcagtgaaaccatttcaagtaaaaaaccatatatgggtttttattaat
tgccttattgaaaatccaacttttgattctcagactaaggaaaatatgactctgcaaccc
aaaagttttgggtccaaatgccagctgtcagaaaaattttttaaagcagcttctaactgt
ggcattgtagaaagtatcctgaactgggtgaagtttaaggctcagactcagctcaacaag
aagtgttcatcagtcaagtatagtaaaattaaaggtattcctaaactggatgatgctaat
gatgctggtggcaaacattccctggaatgtacactgatattgacagagggagactctgcc
aaatcactggctgtgtctggattaggtgtcattgggcgagacagatacggagtctttcca
ctcaggggtaaaattcttaatgtacgggaagcttctcataaacagatcatggaaaatgca
gaaataaacaacattattaaaatagttggtctacaatacaagaaaagttatgatgatgca
gaatctctgaaaactttacgttatggaaagattatgattatgactgatcaggatcaagat
ggttctcatataaaaggcttgcttattaatttcatccatcacaattggccatcacttttg
aagcatggttttcttgaagagttcattactcctattgtaaaggcgagcaaaaataagcag
gaactttccttctacagtattcctgaatttgatgagtggaaaaaacatatagaaaaccag
aaagcatggaaaataaaatactacaaagggttgggtaccagtacagctaaagaagcaaag
gaatattttgctgatatggaaaggcatcgtatcttatttagatatgctggtcctgaagat
gatgctgccattaccttggcattcagtaagaagaagattgatgacagaaaagaatggtta
acaaattttatggaagatcggagacagcgtaggttacatggcttaccagagcaattttta
tatggtacagcaacaaagcatttgacttacaatgatttcatcaacaaagaattgattctg
ttctcaaactcagacaacgaaagatctataccatctcttgttgatggctttaaaccaggc
caacgaaaagtattatatacctgtttcaagaggaatgataaacgtgaagtaaaagttgcc
cagttggcgggatcagttgctgagatgtctgcttatcatcatggagaacaagcgttaatg
atgactattgtgaatttggctcagaactttgtgggaagtaacaacattaacttacttcag
cctattggtcagtttggaactcggcttcatggtggcaaagatgctgcaagccctcgttac
attttcacaatgttaagctctttagcaagactgcttttccctgctatggatgacaacctg
cttaagttcctttatgatgataatcagcgtgtagagcctgagtggtacattcccataatt
cctatggttttaataaatggtgctgagggaattggtaccggatgggcttgtaaactcccc
aactatgatgctagggaaattgtgaacaatgtcagacgaatgctggaaggcttagatcct
catcccatgcttccaaactacaaaaactttaaagggacgattcaagaacttggtcaaaac
caatatgcagtcagtggtgaaatatttgtggtggataggaacacggtagagattacagag
cttccagttagaacctggacacaggtatacaaagaacaggttttagaacctatgctaaat
ggaacagacaaaacaccagcattgatttctgactataaagagtatcatactgatacaact
gtgaaatttgtggtgaaaatgacagaagaaaaacttgcacaggcagaagctgctggattg
cacaaagtttttaaacttcagacgactcttacttgtaattccatggtactctttgatcat
atgggatgtctgaagaagtatgagactgtgcaagacattttgaaagaattctttgattta
cgattaagttattatggtttacggaaggagtggcttgtgggaatgttgggagctgagtct
tcaaagcttaacaatcaagctcgtttcattttagagaagatacaagggaaaattactata
gagaataggtcaaagaaagatttgattcaaatgttagtccagagaggttatgaatctgac
ccagtgaaagcctggaaagaagcacaagaaaaggcagcggaagaggaagaaacacaaaac
cagcaagatgacagttcctcagattcaggaactcctgcaggccccgattttaattatatt
ttaaatatgtctctgtggtctcttactaaggaaaaagttgaagaactgattaaacagaga
gatgcaaaaggtcgagagctctgtgatgttaaaagaaaatctccttcagatctttggaaa
gaagatttagcagcgttcgttgaagagctagataaagtggaagcgcaagaacgagaagat
attctggctggaatgtctggaaaagcaataaaaggtaaagttggcaaacctaaagtgaag
aagcttcagttggaagagacgatgccctcgccttatggccgaagagtagttcctgagatc
accgccatgaaggcagatgccagcaaaaagttgctgaagaagaagaagggtgatcttgat
actaccatagtaaaagtagaatttgatgaagaattcagtggaacagtagaagggacagga
gaagaggcgttgactccgtcagctcctataaataaaggtcccaaacccaagagagagaaa
aaggagcctggtaccagggtgagaagaacacctgcatcatctgggaaatccaatacaaag
aaagtaaagaaacgaaatccttggtcagatgatgagtccaagtcagaaagtgacttagaa
gaaacagaagctgtggttattccaagagattctttgcttaggagagcggctgctgaaaga
cctaagtacacatttgacttctcagaagaagaggatgatgatgctgatgatgatgatgat
gacaataatgatttagaggagttgaaagttaaagcatctcccataacaaatgatggagaa
gatgaatttgttccttcagatggcttagataaagatgaatatacattttcaccgggcaaa
ccaaaagctactccagagaagccttcgcatgacaaaaaaagccaggattttgggaatctt
ttctcatttccttcatactctcagaagtcagaagatgattcagctaaatttgacagtaat
gaagaagattctgcctctgttttttcaccatcatttggtctgaaaccaacagacaaagtt
ccaagtaaaacagtagctgctaaaaagggaaaaccatcttcagatataacccctaagccc
aagagaacccccaagcagaagaaagtggaggctgtaaactctgactccgattcagaattt
ggtgttccaaagaagactgcagcatccaaaggtaaaggtcgaggggcaaagaaaaggaaa
gcatctggctctgaaaatgaaggtgattataaccctgggaggaaaacatccaaaacgaca
acaagcaagaaaccgaagaaatcatcttttgatcaggattcagatgtggacatcttccca
tcagacttcgcttctgaaccaccttctctgccacgaaccggtagggctagaaaagaagta
aaatattttgcagagtctgatgaagaagaagatgtggattttgcaatgtttaattaa
DBGET
integrated database retrieval system
