Trichechus manatus latirostris (Florida manatee): 101359618
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Entry
101359618 CDS
T05135
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
tmu
Trichechus manatus latirostris (Florida manatee)
Pathway
tmu00230
Purine metabolism
tmu01100
Metabolic pathways
tmu04927
Cortisol synthesis and secretion
tmu04934
Cushing syndrome
tmu05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
tmu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
101359618
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
101359618
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
101359618
09167 Endocrine and metabolic disease
04934 Cushing syndrome
101359618
Enzymes [BR:
tmu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
101359618
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Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PDE8
PAS_9
PAS_3
PAS
PAS_4
PAS_8
DUF3757
DUF4194
Motif
Other DBs
NCBI-GeneID:
101359618
NCBI-ProteinID:
XP_023585215
UniProt:
A0A2Y9QP19
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All DBs
Position
Unknown
AA seq
881 aa
AA seq
DB search
MGCAPSIHVSQSGVIYCRDSDESNSPRQTTSVSQGPAAPLHGLFVQTDATDAVPPSRAAG
PPGAARVHRARAELGSGSSTGSAAPAATTCRGRRRHCCSSAEAETQTSYSSVKVSSAEVR
IGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNISRTPESALECFLDKHHEIIV
IDHRQTRNFDAEAVCRSIRATNPSEHTVILAVVSQTSGDHEEASVLPLLHAGFNRRFMEN
SSVTACYNELIQIEHGEVRSQFKLRNWEVIKQSMAAGKQQDYTENSSIYVNPAFERMMGY
HKGELLGKELAELPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVKITPV
IGQGGKIRHFVSLKKLCCTTDNNKQIHKIHRDSGDNSQTESHSFRYKNRRKESIDVKSIS
SRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLEILRT
TELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLAMPVTINDVP
PYIAQLLDNEESWDFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAWLQVI
EANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHPGRTN
SFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDSKCNIFKNIDRNHYRTLRQAIIDMV
LATEMTKHFEHVNKFVNSINKPIAAEIEGSDCECNPVGKNFPENQMLIKRMMIKCADVAN
PCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDM
FDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDN
NT seq
2646 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcccccagcattcacgtctcgcagagcggcgtgatctactgccgggactcg
gacgagtccaactcgccccgccagaccaccagcgtgtcgcagggccccgcggcgcccctg
cacggcctcttcgtccagaccgacgccaccgacgccgtccccccgagccgcgcggcggga
ccccccggcgccgcccgcgtccacagggcccgcgccgagctgggcagcggcagcagcacg
ggctccgcagcccccgccgcgaccacctgcaggggccggaggcgtcactgctgcagcagc
gccgaggccgagactcagaccagctactctagcgtcaaggtttcttctgcggaggtacgc
attgggcccatgagactgacacaggaccctatccaggttttgctgatctttgcaaaggag
gacagtcagagtgatgggttctggtgggcatgtgacagagccggctacaggtgcaatatc
tctcggactccagagtcagcccttgaatgctttttagataagcaccatgaaattattgtt
attgatcacagacaaactcgaaactttgatgcagaagctgtgtgcaggtcgatccgggcc
acaaatccctccgagcacacggtgatccttgcagtggtttcacaaacatcgggtgaccat
gaagaggcctccgtccttcctcttctccatgcaggcttcaacaggagatttatggagaat
agcagcgtaactgcttgctataatgaactgattcaaatagaacatggggaagttcgctca
cagttcaaattacggaattgggaagtcattaaacagtctatggcagctggtaaacagcag
gattatactgagaactcctcgatatatgtcaaccctgccttcgaaaggatgatgggctac
cacaaaggcgagctcctggggaaagaactcgctgagctgcccaaaagtgacaagaaccgg
gcagaccttctcgacaccatcaacacgtgcatcaagaagggaaaggagtggcagggggtt
tactatgcgagacggaaatccggagacagcatccaacagcacgtgaagatcaccccagtg
attggccaaggagggaaaattaggcattttgtctccctcaagaaactgtgttgcaccact
gacaataataagcagattcacaagattcatcgtgattcaggagacaattctcagacagag
tctcattcattcagatacaagaataggaggaaagagtccattgatgtgaaatcaatatca
tctcgaggcagtgatgcaccaagcctacagaaccgtcgctatccatccatggcaaggatc
cactccatgaccatcgaggctcccatcacaaaggtcataaatataatcaatgcagcccaa
gaaaacagcccagtcacagtagcagaagccttggatagggttttagaaattttacggacc
acagaactgtactcccctcagctgggtaccaaagatgaagatcctcacaccagtgatctt
gtcggaggcctgatgactgatggcttaagaaggttgtcaggaaatgagtatgtgtttact
aagaatgtgcaccagagtcacagtcatcttgcgatgccagtgaccatcaacgatgttccc
ccttatattgctcaattacttgataatgaggaaagttgggacttcaacatctttgaattg
gaagctgttacacataaaaggccattggtttacctgggcttaaaggtcttttcccggttt
ggagtatgtgaatttttgaattgttctgaaaccactcttcgggcttggctgcaagtgatt
gaagccaactaccactcctccaatgcctaccataactccactcatgccgccgacgtcctg
catgccactgctttcttccttggaaaggaaagagtaaagggaagcctggatcagctggat
gaggtggcagcactgattgctgccacagtccatgacgtggatcacccgggaaggaccaat
tccttcctgtgcaatgcaggcagtgaactcgctgtgctctataatgacacagctgtcttg
gagagtcaccacacagccctggccttccagctcacagtcaaggacagcaagtgcaacatt
ttcaagaacattgacaggaaccattatcgaacactgcgccaggctattattgacatggtc
ttggcaacggagatgacaaaacattttgaacatgtgaacaaatttgtgaatagtatcaac
aaaccaatagctgctgagattgaaggcagtgactgtgaatgcaaccctgttgggaagaac
tttcctgaaaaccaaatgctgatcaagcgcatgatgattaagtgtgctgatgtggccaac
ccatgccgccccttggacctgtgcattgaatgggccgggaggatctctgaggaatatttt
gcacagactgatgaagagaagagacaggggctacctgtggtgatgccagtgtttgaccgg
aacacctgtagtatccccaagtcccagatttccttcattgattacttcataacagacatg
tttgatgcttgggatgcctttgcacatctgccagccctgatgcaacatttggctgataac
tacaaacactggaagacattggatgacctaaagtgcaaaagtctgaggcttccgtctgac
aactaa
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