Trichechus manatus latirostris (Florida manatee): 101360352
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Entry
101360352 CDS
T05135
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
tmu
Trichechus manatus latirostris (Florida manatee)
Pathway
tmu05012
Parkinson disease
tmu05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
tmu00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
101360352
05022 Pathways of neurodegeneration - multiple diseases
101360352
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tmu01001
]
101360352
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
tmu04131
]
101360352
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
tmu04147
]
101360352
Enzymes [BR:
tmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101360352
Protein kinases [BR:
tmu01001
]
Serine/threonine kinases: TKL group
LRRK family
101360352
Membrane trafficking [BR:
tmu04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
101360352
Exosome [BR:
tmu04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
101360352
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Roc
LRR_8
COR
LRR_4
Ras
LRR_9
Arf
Ank_2
nSTAND3
AAA_22
PduV-EutP
T2SSE
GTP_EFTU
WD40_like
ABC_tran
AAA_7
LRR_6
AAA_16
NB-ARC
TrwB_AAD_bind
MMR_HSR1
cobW
Septin
Kdo
MobB
TniB
G-alpha
AAA_29
SRPRB
FtsK_SpoIIIE
TsaE
ResIII
NACHT
Arm
SRP54
AAA_23
Motif
Other DBs
NCBI-GeneID:
101360352
NCBI-ProteinID:
XP_023594643
UniProt:
A0A2Y9RSP7
LinkDB
All DBs
Position
Unknown
AA seq
2508 aa
AA seq
DB search
MASGNCQGCEEENEGTLKKLIVRLNNVQEGKQIQTLVQILEDMLVFTYADHASKLFQGKN
IHVPLLIVLDSYIRVACVQQVGWSLLCKLIEICPDTMQNLIGPQDVGHDWEVLGVHQLIL
KLLTVHNANVNLSIVGLKALDLLLTSGKITLLILDEESDIFLLIFDAMRMFPANDEVQKL
GCKALHVLFERVSEEQLTEFIENKDYMILLTALKNFKDEEEIVLHVLHCLHSLAIPCNNV
EVLMSGNVRCYNIVVEAMKAFPINEKIQEISCCLLHRLTLGNFFNILVLNEVHTFVVKAV
KQYSENATLQISALSCLALLTETIFLNQDLEEKNENQESDTEEEEDKLFWLEACYKALTW
HRKNKHVQEAACWALNNLLMYQNNLHEKIGDEDGQFPAHREVMLSMLMHSSSKEVFQASA
NALSTLLEQNVNFRKILLSKGIYLNVLELMQKHIYSPEVAESGCKMLNHLFEGSNTALDT
MAAVAPKIITVMKSHETSLSVQLEALRAILHFIVPGMPEESREDTESQHKLNMVKKQCFW
NDIHKLVLAALNRFIGNPGIQKCGLKVISSVAHFPDALEILSLEGAIDSVLHTLQMYPDD
QEIQCLGLSLIGCLIMKKNLCVGTGHLLAKILVSSLQRFKDVAEVQMNGFQAILAILELS
ESFSKLLMHHSFDSVIFCHMSSSINEQKNQQFLNLCCKCFAKLAMDDELKSVMLERACDQ
NNSIMVECLLLLGADANQARESTSLICQVCEKESSPKLVELLLNSGPREQDVRKALTISI
GKGDSQIISLLLQRLALDLANNSICLGGFCMGKIEPSWLGPLFPDKTSNLRKQTNIGSTL
ARMVLRYQMKSAGEEGAASGSDGNFSEDVLVKFDEWTFIPDSSMDCVFGQSDDLDSEGSE
GSFLVKKKSNSISVGEFYRDPALQHCSPNLQRHSNSLGPIFDQEDLLKRRRKILSSDDSL
RSSKLQSHMRNSDSTSSLASEREYITSLDLSSNELRDIDALSQKCCISGHLEHLEKLELH
QNALSSFPQQLCETLKCLTHLDLHSNKFTAFPSYLLKMNCIANLDVSRNDIGPSVILDPV
VRCPTLKQFNMSYNQLSSMPENLAVVVEKLEQLILEGNKISGICSPLSLKELKVLNLSKN
HISSLSENFLEACPKVESFSARINFLAAMPFLPSSITSLKLSQNKFTCIPEAILNLPHLR
SLDMSSNNIQYLPGPAHWKSLNLRELLFSSNQISILDLSEKAHAWSRVEKLHLSRNKLKE
IPPEIGCLENLTSLDVSYNLELRSFPNEMGKLSKIWDLPLDELRLNFDFKHIGCKAKDII
RFLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKTKKSDLGMQSATVGIDVKDWPIQ
IRGKRKKDLVLNVWDFAGREEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWLFNIK
ARASSSPVILVGTHLDVSDEKQRKACISKITKELLNKRGFPAIRDYHFVNATEESDALAK
LRKTIINESLNFKIRDQPVVGQLIPDCYVELEKIILLERKNVPVEFPVVDRKRLLQLVTE
NQLQLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPRWLCKVMAQILTVKVEGYP
KHPKGIISRRDVEKFLSKKRRFPKNYMSQYFKLLEKFQIALPIGEEYLLVPSSLSDHRPV
IELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISPYMLSGRERALRPNRMYWRQGIY
LNWSPEAYCLVGSEVLDYHPESFLKITVPSCRKGCILLGQVVDHIDSLMEEWFPGLLEID
ICGEGETLLKKWALYSFNDGEEHQKILLDDLMKKAEEGDLLINPDQPRLTIPISQIAPDL
ILADLPRNIMLNSDELEFEQAPEFLLGDGSFGSVYRAAYGGEEVAVKIFNKHTSLRLLRQ
ELVVLCHLHHPSLIFLLAAGIRPRMLVMELAPKGSLDRLLQQDKASLTRTLQHRIALHVA
DGLRYLHSSMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTSEGTPGFR
APEVAKGNVIYNQQADVYSFGLLLYDILTTGDRIVEGLKFPNEFDELAIQGKLPDPVKEY
GCAPWPMVEKLIKKCLKENPQERPTSAKVFDILNSAELVCLMRYILLPKNFAVECMVATN
PNSKNASIWLGCGHSDKGQLSFLDLNTEAHTSEEVTDSRILCLALVYLPVEKESWIVSGT
QSGNLLVINTEDGKRRHTLEKMTDSVTCLYCNSFSKQSKQKNFLLVGTADGNLAIFEDKA
VKCKGVAPLKILNIGNVSTPLMCLSESMNSAEKNIMWGGCGTKIFSFSSDFSIQKLIETK
TNQLKHPESKAKKKMTHLLYILIVDKVINILYGFREEMVKSSKESKHKMSYSGRVKTLCL
QKNTALWIGTGGGHILLLDLSTRRIIRIIHNFCDSIRVMITAQLGSLKNVMLVLGYNRKS
TEGTQHQKEIQSCLSVWDINLPHEVQNLEQHIEVRKELAEKMRRISVE
NT seq
7527 nt
NT seq
+upstream
nt +downstream
nt
atggccagtggcaactgtcaggggtgcgaagaggagaacgagggaactctgaagaagttg
atagtgaggctgaacaatgtccaggaaggaaaacagatacagacgctagtccaaatcctg
gaggatatgctggtgttcacatacgctgaccacgcctccaagttatttcaaggcaaaaat
atccacgtgcctctgttgatcgtcctggactcgtacataagagttgcgtgtgtgcagcag
gtgggttggtcacttctatgcaagttaatagaaatctgtccagatacaatgcagaactta
ataggaccccaggatgttggacatgattgggaagtccttggtgttcaccaattgattctt
aaattgttaacagttcacaatgccaatgtaaacctgtcaatagttggactgaaggcctta
gatctcctcctaacttcaggtaaaatcactttgctgatattagatgaggaaagtgatatt
ttcttgttaatttttgatgccatgcgcatgtttccagccaatgacgaagtccagaaactt
ggatgcaaggctttacatgtgctcttcgagagagtttcagaggagcaactaactgaattt
attgagaacaaagattatatgatattgttgactgcattaaaaaattttaaagatgaagaa
gaaattgtgcttcatgtacttcactgtctacattccctagcaattccttgcaataatgtt
gaagtcctcatgagtggcaatgtcaggtgttataatattgtggtagaagctatgaaagca
tttcctattaatgaaaaaatccaggaaatcagttgctgcttgctccataggcttacatta
ggtaatttttttaatattctggtattaaacgaggtccacacgtttgtggtgaaagctgtg
aagcagtattcagagaatgcaacattacaaatctcggcactcagctgtttagcactcctc
actgagaccattttcttaaatcaagacttagaggaaaagaatgagaatcaggagagtgat
actgaagaggaagaagataaattgttttggctggaagcctgttacaaagcattaacgtgg
catagaaagaacaagcacgtgcaggaggccgcatgctgggcactaaataatctcctcatg
taccaaaacaatttacacgagaagattggagatgaagatggccagttcccagctcatagg
gaagtgatgctgtccatgctgatgcattcttcatcaaaagaagtcttccaggcatctgcg
aatgcattgtcgactctgttagaacaaaacgttaatttcagaaaaatcctgttgtcaaaa
ggaatatacctgaacgtattggagttaatgcagaagcatatatactctcctgaagtggct
gaaagtggctgtaaaatgctaaatcatctttttgaaggaagtaatactgccctggataca
atggcagcagtggcccccaaaataataacagttatgaaaagtcacgagacatcattatca
gtgcagctggaggcacttcgagctattttgcattttatagttccaggcatgccagaagaa
tccagggaggatactgaatcacaacataagctaaatatggttaaaaaacagtgtttctgg
aatgatattcacaaactggtcctagcagctttgaacaggttcattggaaatcctgggatt
cagaaatgtggattaaaagtcatttcttctgtagcacattttcctgatgcgttagagata
ttatccctggaaggtgctattgattcagtacttcacacactgcagatgtatccagatgac
caagaaatccagtgtctgggtttaagtcttataggatgcttgattatgaagaagaattta
tgtgtgggaactgggcatctgctggcaaaaattctggtttccagcttacaacgatttaag
gatgttgctgaagtacagatgaatggatttcaggcaatcttggcaatacttgaattgtca
gaatctttttccaagcttctgatgcatcattcatttgactcagtaatcttctgtcatatg
tcttccagcatcaacgaacaaaagaatcaacagttcctaaatctttgttgcaagtgtttt
gcaaaattagctatggatgatgagttaaaaagtgtgatgctagagagagcatgtgatcag
aataacagtatcatggttgaatgcttgcttctattgggagctgacgccaatcaagcaagg
gagtcaacttccttaatttgtcaggtgtgtgagaaagagagcagtcccaagttagtggaa
ctgttattgaatagtggaccccgtgaacaagatgtccggaaagccctgacaataagcatt
gggaaaggtgacagccaaatcatcagtttgctcttacagaggcttgccctggacctggcc
aataatagcatctgccttggaggattttgtatgggaaaaattgagccttcttggcttggt
cctttatttccagataagacatctaatttaagaaagcaaacaaatataggatccacccta
gcaagaatggtgctcagatatcagatgaaaagtgctggtgaagaaggagcagcctcaggc
agtgatgggaacttttctgaagatgtacttgttaaatttgatgaatggaccttcattcct
gactcttctatggactgtgtgtttggtcaaagtgatgatctggatagcgaaggaagtgaa
ggatcatttcttgtgaaaaagaagtcaaattcaattagtgtgggagaattttaccgagat
ccggccttgcaacattgttcaccaaatttgcaaaggcattccaattcactgggacctatt
ttcgatcaagaagacttgctgaaacgaagaagaaaaatattatcttcagatgattcactt
aggtcatcaaaacttcaatcccatatgaggaattcagacagcacttcttccctggcttct
gagagagaatatattacatccttagacctttcatcaaatgaactaagagatattgatgcc
ctaagccagaaatgctgcataagtggtcatttggagcatcttgaaaagctggagcttcac
cagaatgcactctcaagctttccacaacagctttgtgaaactctgaagtgtttgacccat
ttggacttgcatagcaataaatttacagcatttccttcttacttgttgaaaatgaattgc
attgccaaccttgatgtctctcggaatgacatcgggccctctgtaattttggatcctgtg
gtaaggtgtccaaccctgaaacagtttaacatgtcatataatcagctgtcttctatgcct
gagaacctcgctgttgtggtagagaagctggagcagctcattttagaaggaaataaaata
tcaggaatatgttcccccttgagtctgaaggaactgaaggtcttaaaccttagtaaaaac
cacatttcatccctgtcagagaatttccttgaggcttgtcctaaagtggagagtttcagt
gccagaataaattttcttgctgcaatgcctttcttgccttcttccataacaagcctaaaa
ttatctcaaaacaaatttacatgtattccagaagcaattttaaatctaccacatttgcgg
tccttagatatgagcagcaataatattcagtatctaccgggccctgcacactggaaatct
ttgaacttaagagaactcttgtttagctctaatcagatcagcatcttggacttgagtgag
aaagcacatgcatggtctagggtagagaaactacatctctctcgtaataaactgaaagag
attcctcctgagattggctgccttgaaaatctgacatctcttgatgttagttacaacttg
gaactgagatcctttcccaatgaaatgggaaaattaagcaaaatatgggatcttcctttg
gatgaactgcgtcttaattttgattttaaacatataggatgtaaagccaaagacatcata
aggtttcttcaacagcggttaaaaaaggctgtgccctataaccgaatgaaacttatgatt
gtggggaatactgggagtggtaaaaccactttattgcagcaattaatgaaaaccaagaaa
tcagatcttggaatgcaaagtgccacagttggcatcgatgtgaaagactggcctatccaa
ataagaggcaaacggaagaaagacctggttctaaatgtgtgggattttgcgggtcgtgag
gaattctacagtactcatccccacttcatgactcaacgagcattgtatcttgctgtctat
gacctcagcaaaggacaagctgaagttgatgcaatgaagccttggctcttcaatataaag
gcacgtgcttcttcttcccctgtgattcttgttggcacacatttggatgtttctgatgag
aagcaacgcaaagcctgcataagtaaaatcaccaaggaactcttgaacaagcgagggttc
cctgcaatacgggattaccactttgtgaatgccaccgaggaatctgatgctttagcaaaa
cttcggaaaaccattataaatgagagccttaatttcaagatccgagaccagcctgttgtt
gggcagctgattccagactgctatgtagaacttgagaaaatcattttattggagcgtaaa
aatgtgccagttgaattccctgtagttgaccggaaacgattattacaactagtgacagaa
aatcagctgcagttagatgaaaacgagcttcctcatgcggttcacttcctgaatgaatca
ggggtcctgcttcattttcaagacccagcactgcagctaagtgacttatactttgtggaa
cccaggtggctttgtaaagtcatggcacagattttgacagtgaaagtggaaggctatccg
aaacatcctaagggaattatttcacgtagagatgtggaaaagttcctttcaaagaaaagg
agatttccaaagaactacatgtcacagtactttaaactcctagaaaaattccagattgcc
ttgccaataggagaagaatatttgctggttccaagcagtttgtctgatcacaggcctgtg
atagagcttccccattgtgagaactcagagattattattcgactgtatgaaatgccttat
tttccaatgggattttggtctagattaatcaatcgattacttgaaatttcaccttacatg
ctttcaggaagagaacgagcacttcgcccaaacagaatgtactggcgacaaggcatctac
ttgaattggtctcctgaagcttattgcctggtaggatccgaagtcttagattatcaccca
gaaagtttcttaaaaattacagttccttcttgtagaaaaggctgtattcttttgggccaa
gtcgtggatcacattgattctctcatggaggaatggtttcctgggctactggaaattgat
atttgtggtgaaggagaaactctgctgaagaaatgggcattgtatagttttaatgatggt
gaagagcatcaaaaaatcttactggatgacctaatgaagaaagcagaagaaggagacctc
ttaataaatccagatcaaccaaggctcaccattccaatatctcagatcgctcctgacttg
attttggctgatctgcctagaaatattatgttgaatagtgatgaactagaatttgaacaa
gctccagagtttctcttaggtgatggcagttttggatccgtttatcgagctgcctatgga
ggagaagaagtggctgtgaagatttttaataaacatacgtcgcttaggctgttaagacaa
gagctggtggtgctttgccacctccaccaccccagcttaatatttttgctggcagctggg
attcgtcctcgaatgttggtgatggaattagcccccaagggctccctggatcgcctgctt
cagcaggacaaagctagcctcacccgaaccctgcagcacaggatcgcactgcatgtggct
gatggcttgaggtatctccactcatctatgattatataccgtgacttgaaacctcacaac
gtgttgctttttaccctgtaccccaatgctgccatcattgcaaagattgctgactacgga
attgctcagtattgctgtagaatgggaataaagacatcagagggcacaccagggtttcgt
gcacctgaagtggccaaaggaaatgttatttataaccaacaagctgatgtttattcattt
ggtttactactctatgacattttgacaactggagatagaatagtagaaggtttgaagttt
ccaaatgaatttgatgaattggcaatacaaggaaaattaccagacccagttaaagaatat
ggttgtgctccatggcctatggttgagaagttaattaaaaaatgtttgaaggaaaatcct
caagaaaggcctacttctgccaaggtttttgacattttgaattcagctgagttagtctgc
ctgatgagatatattttattgcctaaaaactttgctgttgaatgcatggtggctacaaat
cctaacagcaagaatgcaagcatctggctgggctgtgggcacagtgacaaaggacagctc
tcctttcttgacttgaatactgaagcacacacttctgaggaagttactgatagtagaata
ttgtgcttggccttggtgtaccttcctgttgaaaaggaaagctggattgtgtctggaaca
cagtctggcaatctcctggtcatcaatactgaagatgggaaaaggaggcatacacttgaa
aagatgactgattctgttacttgtttgtattgcaattcgttttccaagcaaagcaaacaa
aaaaatttccttttggtgggaactgctgatggaaatttagcaatttttgaagataaagct
gttaagtgtaaaggagttgctcctttgaagatactaaatataggaaatgtcagcactccg
ctgatgtgtttgagtgaatccatgaattcagctgaaaaaaacataatgtggggaggatgt
ggcacaaagattttctcattttctagtgatttcagcattcaaaagctcattgagacaaag
acgaatcagctcaaacatccagaaagtaaagcaaagaagaaaatgacacatctattatat
atcttaattgttgataaagttattaacatactttatggttttagggaagaaatggtaaaa
tcaagcaaggaatcaaaacacaaaatgtcttattcggggagagtgaaaactctctgcctc
cagaagaacactgctctctggataggaaccggaggaggccacattttacttcttgacctt
tcgactcgtcgaattatacgaataattcacaacttttgtgattctattagagtcatgata
acagcacagttaggaagccttaaaaatgtcatgctggttttggggtataatcggaaaagt
actgaaggtacgcaacaccaaaaagagatacaatcttgcttgtctgtttgggacatcaat
cttccacatgaagtgcaaaatttagaacaacacattgaagtaagaaaagaattggctgaa
aaaatgagaagaatatctgttgaataa
DBGET
integrated database retrieval system
