Thermotoga maritima MSB8: THMA_1271
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Entry
THMA_1271 CDS
T03902
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
tmw
Thermotoga maritima MSB8
Pathway
tmw00230
Purine metabolism
tmw01100
Metabolic pathways
tmw01110
Biosynthesis of secondary metabolites
Module
tmw_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
tmw00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
THMA_1271
Enzymes [BR:
tmw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
THMA_1271
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Motif
Pfam:
PurL_C
AIRS
AIRS_C
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AKE29020
UniProt:
Q9X0X3
Structure
PDB
PDBj
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Position
1270505..1272316
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AA seq
603 aa
AA seq
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MKLRYLNILKEKLGREPTFVELQAFSVMWSEHCGYSHTKKYIRRLPKTGFEGNAGVVNLD
DYYSVAFKIESHNHPSAIEPYNGAATGVGGIIRDVLAMGARPTAIFDSLHMSRIIDGIIE
GIADYGNSIGVPTVGGELRISSLYAHNPLVNVLAAGVVRNDMLVDSKASRPGQVIVIFGG
ATGRDGIHGASFASEDLTGDKATKLSIQVGDPFAEKMLIEAFLEMVEEGLVEGAQDLGAG
GVLSATSELVAKGNLGAIVHLDRVPLREPDMEPWEILISESQERMAVVTSPQKASRILEI
ARKHLLFGDVVAEVIEEPVYRVMYRNDLVMEVPVQLLANAPEEDIVEYTPGKIPEFKRVE
FEEVNAREVFEQYDHMVGTDTVVPPGFGAAVMRIKRDGGYSLVTHSRADLALQDTYWGTL
IAVLESVRKTLSVGAEPLAITNCVNYGDPDVDPVGLSAMMTALKNACEFSGVPVASGNAS
LYNTYQGKPIPPTLVVGMLGKVNPQKVAKPKPSKVFAVGWNDFELEREKELWRAIRKLSE
EGAFILSSSQLLTRTHVETFREYGLKIEVKLPEVRPAHQMVLVFSERTPVVDVPVKEIGT
LSR
NT seq
1812 nt
NT seq
+upstream
nt +downstream
nt
atgaagttgagatatctgaacattctcaaggagaagcttggaagagaacccaccttcgtc
gagcttcaggctttttcagtcatgtggagcgaacactgtggatactcccacacgaagaaa
tacataagaagattaccgaaaacgggttttgagggaaacgcgggtgtggtgaacctggat
gattactattccgttgctttcaagatagagagccacaatcacccgagtgcgatagaacct
tacaacggtgcagcaacgggtgtcggtggaatcatcagagacgtcctcgcgatgggagcc
cgcccaacggccatattcgattcactccacatgtcccgaatcatagacggtatcatagag
ggaatagccgattacggtaattccataggcgttccaacggtcggtggagaactcaggatc
tcctcactatacgcgcacaaccccctcgtgaacgtgctcgcagcgggtgttgtgagaaac
gacatgctggtcgattcgaaagcatcgagaccgggacaggtcatagtgatcttcggagga
gccacaggaagggacggaatccacggggcgtctttcgcttcggaggatctcacgggtgat
aaggcaaccaagctttcaattcaggttggtgacccgttcgctgaaaagatgctcatagaa
gcgttcctggagatggtggaagagggactcgtggaaggagctcaggatctgggagcgggc
ggtgtgctgtccgcaacttcggaactcgtagcgaaggggaatctcggagcgatcgttcat
ctggaccgtgttcccctgagagaaccggatatggagccctgggaaatcctcataagcgaa
agccaagaaagaatggcggtcgtcacatcacctcagaaggcgagccgcattctggaaata
gccaggaagcaccttcttttcggcgatgtcgttgccgaagtgatagaagaaccagtttac
agggtgatgtacagaaacgatctcgtcatggaagttcccgtccagctcctcgcaaacgcc
ccagaagaggacatagtcgaatacacacccggaaagatcccagagttcaaaagggtggaa
ttcgaagaggtgaacgcgagggaagtcttcgagcagtacgatcacatggtcggaacggat
accgtggttccacccggattcggcgcggccgtgatgagaataaagagagacggggggtac
tccctcgtcacacacagcagggcggatctggctcttcaggatacctactggggaaccctc
atagccgtgctcgagagtgtgagaaagacgctcagcgttggtgcggaacccctcgctata
acgaactgcgtgaactacggggatcccgatgttgatccggtgggactttcggccatgatg
accgctctcaagaacgcttgcgaattctccggtgttcccgttgcatcgggaaacgcttct
ctctacaacacgtaccagggaaaacccattccacccaccctggttgtgggaatgttgggg
aaggtgaacccgcagaaagtggcaaaaccgaagccttcgaaggtgttcgcggtgggatgg
aacgacttcgaactcgaaagggaaaaagaactctggagagccataagaaaactctcagaa
gaaggtgctttcatcctctcttcgtcacagcttctgacgagaactcacgtggagactttc
agagagtacggcttgaagatcgaagtgaaactgccagaagtgaggccggcgcatcagatg
gtgctcgtcttctctgagagaactcccgtagtcgatgttcctgtgaaggagatcggaacg
ctctcgaggtga
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