Thermococcus nautili: BD01_0352
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Entry
BD01_0352 CDS
T03065
Name
(GenBank) Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)
KO
K23144
UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:
2.7.7.23
2.7.7.24
2.7.7.83
2.3.1.157
2.3.1.276
]
Organism
tnu
Thermococcus nautili
Pathway
tnu00520
Amino sugar and nucleotide sugar metabolism
tnu00521
Streptomycin biosynthesis
tnu00523
Polyketide sugar unit biosynthesis
tnu00525
Acarbose and validamycin biosynthesis
tnu00541
Biosynthesis of various nucleotide sugars
tnu01100
Metabolic pathways
tnu01110
Biosynthesis of secondary metabolites
tnu01250
Biosynthesis of nucleotide sugars
Module
tnu_M00909
UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc
Brite
KEGG Orthology (KO) [BR:
tnu00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
BD01_0352
00541 Biosynthesis of various nucleotide sugars
BD01_0352
09109 Metabolism of terpenoids and polyketides
00523 Polyketide sugar unit biosynthesis
BD01_0352
09110 Biosynthesis of other secondary metabolites
00521 Streptomycin biosynthesis
BD01_0352
00525 Acarbose and validamycin biosynthesis
BD01_0352
Enzymes [BR:
tnu01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.157 glucosamine-1-phosphate N-acetyltransferase
BD01_0352
2.3.1.276 galactosamine-1-phosphate N-acetyltransferase
BD01_0352
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.23 UDP-N-acetylglucosamine diphosphorylase
BD01_0352
2.7.7.24 glucose-1-phosphate thymidylyltransferase
BD01_0352
2.7.7.83 UDP-N-acetylgalactosamine diphosphorylase
BD01_0352
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Paralog
Gene cluster
GFIT
Motif
Pfam:
NTP_transferase
Hexapep
NTP_transf_3
LbH_EIF2B
Hexapep_2
IspD
GMPPB_C
Motif
Other DBs
NCBI-ProteinID:
AHL21978
UniProt:
W8NRX0
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Position
complement(302888..304144)
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AA seq
418 aa
AA seq
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MKGVILAAGKGERLRPLTDDRPKVVLKVANRPIIEYVLENLYPFVDEFVIVVRYRSEWIK
KTLGDEFGGKPITYVEQLPGEGTAKAIESARESVEDEFIVANGDIYFEEEAVRELVSAFR
REKADVAIVVKHFEDLSHFGKVEVEGSRVTRIAEKPGKIAGYANLGIYAFRSSVFDFIEK
TGLSERGEYEITDTINLMIDAGLKVVAVPYDGYWNDVGRPWNLLELNEYLLKNRLRHEIR
GTVEEGAVIVPPVEIGEGTVVRSGAYIIGPVKIGRNSRIGPNCFIRPYTSIGDNCHIGNA
VEVKNSIIMDNSNAPHLNYVGDSIIGENTNLGAGTITANLRHDRGNVKVEIKGKLEDSGR
HKLGAIIGHNVKVGINVSIYPGRKIGSNSFIGPGVIVDRNVPPNSLVVVRQEKLVMEK
NT seq
1257 nt
NT seq
+upstream
nt +downstream
nt
gtgaagggtgtaatcctcgcagctggaaagggtgaaaggctccgccccctcacggacgac
aggccgaaggtggttctcaaggtcgccaaccggccgataatcgagtacgtcctcgagaac
ctgtacccgttcgttgacgagttcgtgattgtggttaggtatcggagcgagtggataaag
aagacccttggagacgagttcgggggcaagccgataacctacgtggagcagttgcccgga
gagggaacggcgaaggccatagagagcgccagggagagcgtggaggacgagtttatagtt
gcaaacggtgacatctacttcgaggaggaggcggttagggagctcgtctcggccttcagg
agggagaaagcggacgtcgccatcgtcgtcaagcacttcgaggatttgagtcacttcggc
aaggtcgaggttgaaggctcaagggtaacgcgcatagccgaaaagcccggcaaaatagcg
ggttacgccaacctcggcatctacgccttccgttcgagcgtcttcgacttcatagagaaa
accggcctgagtgagcgcggggagtacgagataaccgacacgattaacctcatgattgac
gccgggcttaaggttgtggcggttccctacgacggctactggaacgacgtcggaaggccg
tggaatttactcgagctcaacgaatacctgctcaagaacaggctcaggcacgagattaga
ggaacggtcgaggaaggggcggtgatagttccccccgttgaaatcggcgagggaaccgtc
gtcaggagtggggcctacataatcgggcccgtgaagattggcaggaactcccggataggg
ccgaactgcttcataaggccgtacacgagcataggcgacaactgccacatcggcaacgcg
gttgaagtcaagaactccatcataatggacaacagcaacgcaccgcacctcaactacgtc
ggcgactcgataataggagaaaacacgaacctcggcgcggggacgataacggcaaacctg
aggcatgacaggggcaacgtcaaggttgaaatcaaggggaagctcgaggacagcggcagg
cacaagctcggggcgataatcggacacaacgtaaaggttggtatcaacgtcagcatctat
ccgggcaggaagattgggagcaactcttttatagggccgggcgttatcgttgaccgcaac
gtcccgccaaacagcctcgtggtagtgaggcaggagaagttggtgatggagaaatga
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