Talpa occidentalis (Iberian mole): 119230391
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Entry
119230391 CDS
T07495
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
119230391 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
tod03032
]
119230391 (TOP2A)
03036 Chromosome and associated proteins [BR:
tod03036
]
119230391 (TOP2A)
Enzymes [BR:
tod01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
119230391 (TOP2A)
DNA replication proteins [BR:
tod03032
]
Eukaryotic type
DNA Topoisomerases
119230391 (TOP2A)
Chromosome and associated proteins [BR:
tod03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
119230391 (TOP2A)
Centrosome formation proteins
Centriole proteins
119230391 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Motif
Other DBs
NCBI-GeneID:
119230391
NCBI-ProteinID:
XP_037347352
LinkDB
All DBs
Position
Unknown
AA seq
1535 aa
AA seq
DB search
MEVSPLQPVNENMQANKTKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDVGMNYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWMDNMGRAGEMELKPFHGEDYTCITFKPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNKLPIKGFRSYVDMYLKDKVDETGNPLKIIHEQVNHRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYIADQIVTKLVDVVKKKNKGGVAVKSHQVKNHM
WIFVNALIENPTFDSQTKENMTLQVKSFGSTCQLSEKFIKAATGCGIVESILNWVKFKAQ
VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEIAFYSLPEFEEWKS
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD
RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPAKDDHTLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFKGTIE
ELASNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAEAEKVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDTEKETEKSASAADSGPTFNYLLDMPLWYLTKEK
KDELCKLRNEKEQELEILKRKSPSDLWKEDLAAFVEELEVVEAKEKQDEQVGLSGKGGKA
KGKKGQMVEVLPSPSGKRVIPRVTVEMKAEAEKKIKKKIKNENAEGSPQEDGMELEGLKQ
RLEKKQKREPGTKTKKQTTLPFKPIKKVKKRNPWSDSESDMSSDESNFDVPPREVEPRRA
APKTKFTVDLDSDDDFSDFHEENQNEDFVPLDASPPKPRTSPKHTNKDLKPQKSAMSVTD
LNADDPKNSVPVSSSSSAADFPAETGIINPVSKKSATVKKTTAKSQPPTSTTGAKKRAAP
KKTTKKDPGLDSDVSQKTDAPKTKIRRKRKPSTTSDDSDSNFEKVISKAVTSKKSKGESD
DFHLDIDSAVAPRAKSGRTKKPIQYLEESDEDDLF
NT seq
4608 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcacctctgcagcctgtaaatgaaaatatgcaagccaacaagacaaagaaa
aatgaagatgctaagaaaagactgtctattgaaaggatctatcaaaagaaaacccaattg
gaacatattttgctccgcccagacacctacattggctctgtggaattagtgacccagcaa
atgtgggtttatgatgaagatgttggcatgaactatagggaagtcacttttgttcctggt
ttgtacaaaatctttgatgagattctagtcaatgcagcagacaacaaacaaagggaccca
aaaatgtcttgtattagagtcacaattgacccggaaaataatttaattagtatatggaat
aatgggaaaggtattcctgttgttgaacacaaagttgagaagatgtatgtcccagctctc
atctttggacagctcctaacttctagcaactatgatgatgatgaaaagaaagtaacaggt
ggtcgaaatggctatggagccaaattgtgtaacatattcagtaccaaatttactgttgaa
acagccagtagagaatacaagaaaatgtttaaacagacatggatggataacatggggaga
gctggtgagatggaactcaaaccctttcatggagaagattatacatgtattacctttaaa
cctgacttgtctaagtttaaaatgcaaagcctggacaaagatattgttgctcttatggtt
agaagagcatatgatattgctggatccactaaagatgtcaaagtctttctgaatggaaat
aagctgccaataaaaggatttcgtagctacgtggatatgtatttgaaggataaggtagat
gaaactggtaatccactgaaaattatccatgagcaagtaaaccacaggtgggaagtgtgt
ttaacgatgagtgaaaagggctttcagcaaattagcttcgtaaacagcattgctacttcc
aagggtggcagacatgttgattatatagctgatcagattgtgacaaaacttgttgatgtt
gtgaagaagaagaataagggtggtgttgcagtaaaatcacatcaggtgaaaaatcacatg
tggatttttgtgaatgccttaattgaaaatccaacctttgactctcagactaaagaaaac
atgactttacaagtcaagagctttggatcaacatgccaattaagtgaaaaattcatcaaa
gctgcaactggctgtggtattgtagaaagcatattaaactgggtgaagtttaaggcccaa
gtccagttaaataagaagtgttcagctgtaaagcacaacagaatcaaaggaattccaaaa
cttgatgatgccaatgatgcaggaggtcgaaactccactgagtgtacacttatcctgact
gagggagactcagctaaaactttggctgtttcaggccttggtgtggttgggagagacaaa
tacggggtttttcctcttagaggaaaaatactcaatgttcgagaagcgtctcataaacag
ataatggaaaatgcagaaattaacaatatcatcaagattgtaggtcttcagtacaagaaa
aactatgaagatgaagattcactgaagactcttcgttatgggaagataatgattatgaca
gatcaggaccaagatggatcccatattaaaggcttgctgattaattttatccatcacaac
tggccctctcttttgagacatcgttttctggaggaatttattactcccattgtaaaggtg
tctaaaaataagcaagaaatagcattttatagccttcctgaatttgaagaatggaagagt
tccactccaaatcacaaaaaatggaaagtcaagtattacaaaggtttgggcactagcaca
tcaaaagaagctaaagagtattttgcagatatgaaaaggcatcgtatccaattcaaatat
tctggtcctgaagatgatgctgcaattagcctggcttttagcaaaaaacagatagatgac
cgaaaggaatggttaactcatttcatggaggatagaaggcaacgaaagttacttggcctt
cctgaggattacttgtatggacaaactaccacatatctcacatacaatgacttcataaat
aaggaacttatcctgttctctaattctgataatgagagatctatcccatctatggtagat
ggtttgaaaccaggtcagagaaaagttttgtttacttgtttcaaacggaatgacaagcga
gaggtaaaggttgcccagttagctgggtcagtggctgagatgtcatcttaccatcatggt
gagatgtcactaatgatgaccattatcaatttggctcagaattttgtgggtagcaataat
ctgaacctcttgcagcccattggtcagtttggcaccagactgcatggtggcaaagattct
gctagtcctcgatatatcttcacaatgctcagtcccttggctcggttgttatttccggca
aaagatgatcacactttaaagttcttatatgatgacaaccaacgtgttgagcctgaatgg
tacattcctattatacccatggtgctgataaatggtgctgaaggaattggtactggatgg
tcctgtaaaatccctaattttgatgttcgtgaagttgtaaataatatcaggcgtttgatg
gatggagaagaacctttgccaatgcttccaagttacaagaacttcaagggaacaattgaa
gagctggcttcaaatcaatatgtgattagtggtgaagtggctatccttaattccacaacc
atcgaaatctcagaacttcctatcagaacatggacacagacttataaagaacaagttcta
gaacctatgttgaatggcactgagaagacaccccctctcataacagactatcgggaatat
catacagatacaactgtgaagtttgttgtgaagatgaccgaagaaaaacttgcagaagca
gagaaagttggactacacaaagtcttcaaactccaaacgagtctcacatgcaactctatg
gtgctttttgaccatgtaggctgtttaaagaaatacgacacagtgttagatattctaaga
gacttctttgaactcaggcttaaatattatggattaagaaaagaatggcttctaggaatg
cttggtgctgaatctgctaaactgaacaatcaggctcgctttatcttagagaaaatagat
ggcaaaataatcattgaaaataaaccaaagaaagaattaattaaagttctgattcagagg
ggatatgattcagatcctgtaaaggcttggaaagaagcccagcaaaaggttccagatgaa
gaagaaaatgaagagagtgacactgagaaggaaactgagaagagcgcctctgccgccgat
tctggacccaccttcaactaccttcttgatatgcccctctggtatctaaccaaggagaag
aaagatgaactgtgcaaactgagaaatgaaaaagagcaagagctagaaatattaaagaga
aagagtccatcagatttgtggaaagaagacttggctgcttttgttgaagaactggaggtt
gttgaagccaaggaaaaacaagatgaacaagtaggactttctgggaaaggggggaaagca
aaggggaaaaaaggacaaatggttgaagttttaccctctccaagtggaaaaagagtcatc
ccccgagtgaccgtagagatgaaagcagaagcagaaaagaaaattaaaaagaaaattaag
aatgaaaatgctgaaggaagtcctcaagaggatggtatggaactagaaggcctaaaacaa
agattagaaaagaaacaaaaaagagaaccaggtactaagacaaagaaacagactacattg
ccatttaagccaatcaagaaagtaaagaagagaaatccctggtctgattcggaatcagat
atgagcagtgatgaaagcaattttgatgtccctccacgagaagtagagccacggagagca
gcaccaaaaaccaaattcacagtggatttggattcagatgacgatttctcagattttcat
gaagaaaatcaaaatgaagattttgtcccattagatgctagtccaccgaagcccagaact
tccccaaaacatactaacaaagacctgaagccacagaaaagtgccatgtcagtaacagac
ctcaatgctgatgaccccaagaacagtgtgccagtttcctcaagctcctctgctgctgac
ttcccagctgagacaggaattataaaccctgtttctaaaaagagtgcaacagtgaaaaag
acgacagcaaaaagtcagcctcccacctccactacaggagccaaaaaaagggctgcacca
aaaaagaccaccaaaaaagatccagggctggattctgacgtttctcaaaagactgatgcc
cccaaaaccaagattcgccgtaagaggaagccgtccactacctctgacgattctgactct
aattttgagaaagttatttctaaagcagtcacaagcaagaaatccaagggggagagtgat
gacttccatctggacatagactcagctgtggctcctcgggcaaaatctggacggacaaag
aaacctatacagtaccttgaagaatcagatgaagatgatctgttttaa
DBGET
integrated database retrieval system
