KEGG   Talpa occidentalis (Iberian mole): 119230399
Entry
119230399         CDS       T07495                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
tod  Talpa occidentalis (Iberian mole)
Pathway
tod04010  MAPK signaling pathway
tod04015  Rap1 signaling pathway
tod04218  Cellular senescence
tod04620  Toll-like receptor signaling pathway
tod04664  Fc epsilon RI signaling pathway
tod04668  TNF signaling pathway
tod04714  Thermogenesis
tod04750  Inflammatory mediator regulation of TRP channels
tod04912  GnRH signaling pathway
tod04935  Growth hormone synthesis, secretion and action
tod04936  Alcoholic liver disease
tod05014  Amyotrophic lateral sclerosis
tod05022  Pathways of neurodegeneration - multiple diseases
tod05132  Salmonella infection
tod05135  Yersinia infection
tod05145  Toxoplasmosis
tod05161  Hepatitis B
tod05169  Epstein-Barr virus infection
tod05170  Human immunodeficiency virus 1 infection
tod05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
tod05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tod00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    119230399 (MAP2K3)
   04015 Rap1 signaling pathway
    119230399 (MAP2K3)
   04668 TNF signaling pathway
    119230399 (MAP2K3)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    119230399 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    119230399 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    119230399 (MAP2K3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    119230399 (MAP2K3)
   04935 Growth hormone synthesis, secretion and action
    119230399 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    119230399 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    119230399 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    119230399 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    119230399 (MAP2K3)
   05161 Hepatitis B
    119230399 (MAP2K3)
   05169 Epstein-Barr virus infection
    119230399 (MAP2K3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    119230399 (MAP2K3)
   05135 Yersinia infection
    119230399 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    119230399 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    119230399 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    119230399 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    119230399 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    119230399 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tod01001]
    119230399 (MAP2K3)
Enzymes [BR:tod01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     119230399 (MAP2K3)
Protein kinases [BR:tod01001]
 Serine/threonine kinases: STE group
  STE7 family
   119230399 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Pkinase_fungal Seadorna_VP7 Choline_kinase APH RIO1 DUF4344
Other DBs
NCBI-GeneID: 119230399
NCBI-ProteinID: XP_037347369
LinkDB
Position
Unknown
AA seq 347 aa
MESPASNQPAGMPPSKAKSKRKKDLRISCVSKPPTPNPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDVNMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVD
FTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggagtctccggcctcgaaccagcccgccggcatgcccccgtccaaagcaaagtccaag
aggaagaaggatttacggatatcctgtgtgtctaagccacccacacccaaccccacacct
ccccggaacctggattcccggaccttcatcaccattggagacaggaactttgaggtggag
gctgatgacctggtgaccatatcagagctgggccgtggagcctatggggtggtggagaag
gtgcggcatgcccagagtggaaccatcatggctgttaagcggatccgggccaccgtgaac
tcgcaggagcagaagcgtctgctcatggacttggacgtcaacatgcgcacagtcgactgc
ttctatactgtcacgttttatggggccctcttcagagagggagatgtgtggatttgtatg
gagctcatggacacgtccctggacaagttttaccggaaggtgttggataagaacatgacg
attccagaggacattctgggggagatcgctgtgtctatcgtgagggccctggagcacctg
cacagcaagctgtctgtgatccacagagatgtgaagccatccaacgtcctcatcaacaag
gagggccacgtgaagatgtgcgactttgggatcagcggctacttggtggattctgtggcc
aagacgatggatgctggctgcaagccctacatggctccagagagaatcaaccctgagctg
aaccagaagggctacaatgtcaagtctgacgtctggagcctcgggatcaccatgattgag
atggccattctccggtttccatatgagtcctggggaaccccgttccagcagctgaagcag
gtggtggaggagccatccccccagctcccagctgaccgtttctcccctgagtttgtggac
ttcactgcacagtgcttaaggaagaaccctgcagagcgtatgagctacctggaactgatg
gagcaccctttcttcaccttgcacaaaactaagaagacagacatcgctgcctttgtgaag
gagatcctgggagaggactcatag

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