Talpa occidentalis (Iberian mole): 119230565
Help
Entry
119230565 CDS
T07495
Symbol
ERBB2
Name
(RefSeq) LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod01521
EGFR tyrosine kinase inhibitor resistance
tod01522
Endocrine resistance
tod01524
Platinum drug resistance
tod04010
MAPK signaling pathway
tod04012
ErbB signaling pathway
tod04020
Calcium signaling pathway
tod04066
HIF-1 signaling pathway
tod04151
PI3K-Akt signaling pathway
tod04510
Focal adhesion
tod04520
Adherens junction
tod04530
Tight junction
tod05200
Pathways in cancer
tod05205
Proteoglycans in cancer
tod05206
MicroRNAs in cancer
tod05212
Pancreatic cancer
tod05213
Endometrial cancer
tod05215
Prostate cancer
tod05219
Bladder cancer
tod05223
Non-small cell lung cancer
tod05224
Breast cancer
tod05226
Gastric cancer
tod05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
119230565 (ERBB2)
04012 ErbB signaling pathway
119230565 (ERBB2)
04066 HIF-1 signaling pathway
119230565 (ERBB2)
04020 Calcium signaling pathway
119230565 (ERBB2)
04151 PI3K-Akt signaling pathway
119230565 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
119230565 (ERBB2)
04520 Adherens junction
119230565 (ERBB2)
04530 Tight junction
119230565 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
119230565 (ERBB2)
05206 MicroRNAs in cancer
119230565 (ERBB2)
05205 Proteoglycans in cancer
119230565 (ERBB2)
05230 Central carbon metabolism in cancer
119230565 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
119230565 (ERBB2)
05226 Gastric cancer
119230565 (ERBB2)
05219 Bladder cancer
119230565 (ERBB2)
05215 Prostate cancer
119230565 (ERBB2)
05213 Endometrial cancer
119230565 (ERBB2)
05224 Breast cancer
119230565 (ERBB2)
05223 Non-small cell lung cancer
119230565 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
119230565 (ERBB2)
01524 Platinum drug resistance
119230565 (ERBB2)
01522 Endocrine resistance
119230565 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tod01001
]
119230565 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
tod04147
]
119230565 (ERBB2)
04090 CD molecules [BR:
tod04090
]
119230565 (ERBB2)
Enzymes [BR:
tod01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
119230565 (ERBB2)
Protein kinases [BR:
tod01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
119230565 (ERBB2)
Exosome [BR:
tod04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
119230565 (ERBB2)
CD molecules [BR:
tod04090
]
Proteins
119230565 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Haspin_kinase
Kinase-like
Tcell_CD4_C
Motif
Other DBs
NCBI-GeneID:
119230565
NCBI-ProteinID:
XP_037347713
LinkDB
All DBs
Position
Unknown
AA seq
1259 aa
AA seq
DB search
MELAAWCCWGLLLALLPPGGAGTQVCTGTDMKLRLPASPETHLKMLRSLYEGCQVVQGNL
ELTYLPADANLSFLQDIQEVQGYVLIAHNQVSQVPLQRLRIVRGTQLFEDSYALAVLDNG
GQQDSASPALGATPGGLQELQLRSLTEILKGGVLIQRNPQLCHEDTILWEDIFHKNNHLA
LKQIDSNRSRTCQPCSRTCKDSRCWGPSSEDCQSLTRMVCASGCARCKGPLPTDCCHEQC
AAGCTGPKHSDCLACLNFNHSGICELHCPALVTYNTDTFESMPNPXGRYTFGASCVTSCP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCAPVCYGLGMEHLRDVRAVTSAN
IQKFAGCKKIFGSLAFLPESFEGDPASKTAPLQPEQLSVFDALEEITGYLYISAWPDSLT
DLSVFQNLRVIRGRVLYDGAYSLTLQGLGISWLGLRSLRELGSGMALIHRNARLCFVHMV
PWNQLFRNPHQTILRSANRPENECEAEGQVCDGLCAHQHCWGPGPTQCVNCSHFLRGQEC
VKECRELQGLPREYVKDRHCWPCHSECQPQNGSRTCSGSEADQCVTCAHYKDPPFCVARC
PSGVKADLSFMPIWKFPDEEGTCQPCPINCTHSCVDLDDKGCPAEQRASPVTSIIAAVVG
ILLFVVVGLVLGIVIKRRRQKIRKYTMRRLLQETELVEPLTPSGAVPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEEVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGTGGTAHRRHRSSSTRSGVGELTLGLEPSEEEPPKSPLAPSEG
AGSDVFDGDLGMGAAKGLQSLAPHDPNPLQRYSEDPTVPLPPETDGYVAPLTCSAQPEYV
NQPDIRPQPPSPLEGPLPPRPAGATLERPKTLSPKTLSPGKNGVVKDIFAFGGAVENPEY
LAPRGGAAPQPHPPPTFSPAFDNLYYWDQDPSERGSPPSTFEGTPTAENPEYLGLDVPV
NT seq
3780 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgctgctgggggctcctgctcgccctcctgccccccggaggc
gcgggcacccaagtgtgcaccggcacagacatgaagctgcggctcccagccagtcccgag
acccacctgaaaatgctccgctccctctacgagggctgtcaggtggtacagggtaacctg
gaactcacctacctgcctgccgatgccaacctctcctttctgcaggatatccaggaggtg
cagggctatgtgctcattgctcacaaccaagtgagtcaggtcccactgcagaggctgcga
atcgtgcgaggcacccagctctttgaggacagctacgctctggccgtgctggacaatgga
ggccagcaggacagtgccagccctgctctgggggctacccccggagggctgcaggagctt
cagctacgaagcctcacagagatcctgaagggaggggtcttgatccagcggaacccccag
ctctgccacgaggacaccatactttgggaggacatcttccacaagaacaaccatctggct
ctcaagcagatagacagcaaccgctcccggacttgccagccgtgttctcggacttgtaaa
gactcccgctgctggggaccgagttctgaggactgtcagagcttgacgcgaatggtctgt
gccagtggctgtgcccgctgcaagggcccgctgcccaccgactgctgccacgagcagtgt
gctgctggctgcacgggccccaagcactccgactgcctggcttgcctcaacttcaaccac
agtggcatctgtgagctgcactgcccagctctggtcacctacaacactgacaccttcgag
tccatgcccaacccgnagggccgatacaccttcggcgccagctgtgtgacctcctgtccc
tataactacctctctacggacgtggggtcctgcaccctggtctgtcccttaaacaaccaa
gaggtgacagccgaggatggaacacagcggtgtgagaaatgcagcaagccctgtgcccca
gtgtgctatggcctgggcatggagcacctgcgggacgtgagggcagtcacaagcgccaac
atccagaagtttgctggctgcaagaagatctttggaagcctggcctttctgcctgagagc
tttgaaggtgacccagcctccaaaactgcccccctccagcctgagcagctcagtgtcttt
gatgccctggaggagatcacaggttacctgtacatctcggcatggccggacagcctgact
gacctcagtgtcttccagaacctgcgagtaatccgggggcgagttctatatgacggtgcc
tactccctgaccctgcaagggctgggcatcagctggctggggctgcgctctttgcgggaa
ctgggcagcgggatggccctcatccaccgcaacgcccgcctctgcttcgtgcacatggta
ccctggaaccagctcttccggaacccccaccagaccatcctccgcagtgccaaccggcca
gagaatgagtgcgaggccgagggccaggtctgtgacgggctctgcgcccaccagcactgc
tggggtccggggcccacccagtgtgtcaactgcagccacttccttcggggccaggagtgc
gtgaaggaatgccgagaactgcaggggctcccccgggagtacgtgaaggacaggcactgc
tggccatgccactccgagtgtcagccccagaacggctccaggacctgctctggttcggag
gctgaccagtgcgtgacctgcgcccactacaaggaccctcccttctgcgtggctcgctgc
cccagtggcgtgaaagctgacctctccttcatgcctatctggaagttcccagacgaggaa
ggcacatgccagccatgccccatcaactgtacccactcctgtgtggacctggatgacaag
ggctgccccgccgagcagagagccagccccgtgacgtccatcatcgccgctgtagtgggc
attctgctgtttgtggtcgtggggctggtcctgggcatcgtaatcaagcgaaggcggcag
aagatccgcaagtacacgatgcgcaggctgctgcaggaaaccgagctggtggagccactg
acaccgagtggagctgtgcccaaccaggcccagatgcgtatcctgaaagaaacagagctg
aggaaggtgaaggtgcttggatccggagcttttggcaccgtctataagggcatctggatc
ccagatggggaaaatgtgaaaatcccagtggccatcaaagtgttgagagaaaacacatct
ccgaaagctaataaagagatcctggacgaagcgtatgtgatggctggtgtgggttcccca
tatgtgtcccgcctcctgggcatctgcctgacttccacggtgcagctggtgacacagctc
atgccctatggctgcctcctagaccacgtccgagaacaccgcgggcgcctgggctcccag
gacctgctgaactggtgtgtgcagatcgccaaggggatgagctacctggaggaagtgcgg
ctggtgcacagggacttggctgcccggaacgtgctggtcaagagtcccaaccacgtcaag
attacagactttgggctggctcggctgctagacattgatgagacggaataccatgcagat
gggggcaaggtgcccatcaagtggatggccttggagtccattctccggcggcggttcacc
caccagagtgatgtgtggagctacggtgtgactgtgtgggagctgatgacttttggggcc
aaaccttacgatgggatcccagcccgggagatccctgacctgctggagaagggggaacgg
ctgccccagccccccatctgtaccattgacgtctacatgatcatggtcaaatgttggatg
atcgactctgaatgtcggcctcggttccgggagttggtggctgaattctcgcgcatggcc
agggacccccagcgttttgtggttatccagaatgaggatttgggccctgccagccccttg
gacagtactttctaccgctcgctgctggaagacgacgacatgggggacctggtggatgct
gaggagtacctggtaccccagcagggcttcttctgcccagaccctgccccaggcaccggg
ggcacagcccaccgcagacaccgaagctcatccaccaggagtggtgttggtgaactgaca
ctagggctggagccctccgaagaggagccccccaagtctccactggcaccctcggaaggg
gctggctctgatgtgtttgatggtgacctgggaatgggagcagccaaggggctgcagagc
ctcgccccacatgaccccaaccctctccagcggtacagcgaggaccccacagtacccctg
ccccctgagactgatggttacgttgcccccctgacctgcagcgcccagcctgaatacgtg
aaccagccagacattcggccacagcccccttcgcctttagaaggtcctttgcctcctcgg
cctgccggtgccaccctggaaaggcccaagactctctcccccaagactctctccccaggg
aagaacggggttgttaaagacatttttgccttcgggggtgctgtagagaaccctgagtac
ttggcaccccggggtggggctgctcctcagccccaccctcctccaaccttcagcccagcc
tttgacaacctctattactgggaccaggacccatcagagcggggctctccacccagcacc
tttgaagggactcctacggcagagaaccccgagtacctgggcctggacgtgccagtgtga
DBGET
integrated database retrieval system
