Talpa occidentalis (Iberian mole): 119231214 Help Entry 119231214         CDS       T07495                                  Symbol SETX Name (RefSeq) probable helicase senataxin   KO K10706   ATP-dependent RNA/DNA helicase, senataxin [EC:5.6.2.5 5.6.2.3] Organism tod  Talpa occidentalis (Iberian mole) Pathway tod05014   Amyotrophic lateral sclerosis Brite KEGG Orthology (KO) [BR:tod00001]  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     119231214 (SETX)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03021 Transcription machinery [BR:tod03021]     119231214 (SETX) Enzymes [BR:tod01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.3  DNA 5'-3' helicase      119231214 (SETX)     5.6.2.5  RNA 5'-3' helicase      119231214 (SETX) Transcription machinery [BR:tod03021]  Eukaryotic type   RNA polymerase II system    Other transcription-related factors     Transcription termination factor      119231214 (SETX) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AAA_11 AAA_12 AAA_19 UvrD-helicase AAA_30 AAA_22 ResIII SLFN-g3_helicase Helicase_RecD AAA_16 nSTAND3 UvrD_C_2 Motif Other DBs NCBI-GeneID:  119231214 NCBI-ProteinID:  XP_037348786 LinkDB All DBs Position Unknown AA seq 2646 aa AA seqDB search MSTCCWCTPGGGSTVDFLKCYASKTRSSEFQTADEDLCYCLECVAEYHRARESLQFLHEV LWELETLRLINHFEKSMKGEIGDDDELYIVDNNGEAQLFDFTGQDFENKLRVPLLEILKY PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK VDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKNYWLG ICMLLTILEEQAMDSLLLGSEKQNDFMQSILHTMERQVDDDSVDPFWPALHCFMVILDRL GSKVWGQLIDPIEAFQTIINNVSYNREIQNIRNSSARAKYEPESFLDDMVSCSQIVYNYN PEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMG LKDLGVAYIAGVIHHLHSEVKDVLNQTDVVCDKVTEFFLLILVSVIELHRNKKCLHLLWV TSQQWVEAIVKCAKLPTTAFARSSEKSAGNCSKGSAAVVSSLALHAVPSNSVQLACVQLI RSLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTSRETLELQTCLRQIIKSIKAKA PQHCAYVDLTPACKNPPAVYKKEKNEQIGKKSKKHVHCLENSSPTFSKEPVKTDACQMQE TVLVKATSTIVEDNKQSYVKDSKLQDRPSAELSLKQSSKNHHTERAPGAVRISTRKQKSV KENPSYTPKSSVLRNSPERGCDKGIISTHSLANSSKKPLEKMATSNEDFLKDDARGKTSE TKMKAQKDDICAKLSHVIKKQHRKSTLVGSAINLEENLTHSDIESFFSKKDAAGQKGDGF IHNPGLHPNGILDDKNGEQKSQNSLLLKKQLELGIFSSHDNSGQVQDCRVGDKDLAPLTE MTNTFLKKTSPFEDPLTVFEKRDKESDQSADQVSPDLREQASSASPKSDTLTDSQVDRDL HKLSLIAQASVIKFPSDSTQKSLSPLQGKVKDGFVTNQNAVAEGRCGQVIIISDSDDDDE RMLGFENRIRQDKMCLEKQCLGQRASISDTRVERVIKEEETKSLLQLEESDSQMFEFESQ NKVFSVWQDQELDDKHSAQEDEEKSGLTCKPAVTNQWAYTGYASEEVMEKEGTEERAEAQ SASISVGEFCKVEVKKPKRKRFDKSVDQDPVRSSSANDEYQADSLNEGDLTENDFKIIDI KTVTPSSSTERAAAAPLKRSSPKLRSYSRPIRRVRVSKPKKTHSDTKKGPNRNSSYLTCR TTPAIVPPKKARQCPEPASTAEKFRLKKGPRKAFELSQRSMEYIVQLRDHGKNVGAVDIR KKTKLISPQTLSAKNNKKLLTSQDLQLRRQVRPKSQHSRQELFDNGNAEPRAAQSYDMFA SDSGGSDYKRGAKAAATSNGKQFIQCVSSEPEPMRAKHVSEVTHDTSLSNRCNSVVLNGR ILASEAAASTSAGPAGGGTRATHLATRKEPEPEAGSDMEDDSLFLTQNDPEDMDLCSQME IEPAQGKDAVQVGTHPLGRPQVETPSSRTSKHRDCNEAARAHGDGCATHAEARAADEDVF RKPALPLPPSKPLRPSRTKIFCCTSRSANLSRSLESDAALPPALKTKSSGVQSSVKVPQP AFLGPPKPVAEVKSLCSVLPSQTPAAAGRPPYRLPFAESRSFSPASSGNILLPSQSISDA FVKEVLKWKYDMFVTLDQFGPPASLCHSVCRPVPVRFQDYREYFNVFFPLMILNTFETVA QEWISSPNKEKFYQLHVRKFPTEYEKSWELVVSLEECELAKQLHPKENDLVFLVPEKLSG EKKDAKRNCMQDPHEYYCGYVHKFRRTSVMRNGKSECSLSIQTQDTLPVNLNELVKCIVI SSLVTTQRKLRAMSLLSDQSQLARAVLNPNPMDFSTKDLLTTTSERITAYLRDFNEDQKK AIETAYAMVKHSPAVAKICLIHGPPGTGKSKTIVGLLYRLLTETQRRGHSDENSNAKIKQ NRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGPEKSINNEVLKFS LDSQVNHRMKKDLPSHVQEMHRRKEYLDLQLDELSRQRALCRVGREMQKQELDEKIASVS KERQELASKIKEVQGRPQKTQSIIILESHVICCTLSTSGGLLLESAFRRQGGVPISCVIV DEAGQSCEVETLTPLIHRCNKLILVGDPKQLPPTVISMKAQEYGYDQSMMARFCKLLGEN VEHDVMSRLPIVQLTTQYRMHPDICLFPSNYVYNRNLKTNRVTETSRCSSDWPFQPYLVF DVGDGAERRDNDSYVNVQEIKLVMEIIKLIKDKRRDVTFRNIGIITHYKAQKTMIQKDLD REFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANTSQGSIGFLASLQRLNVTITRAKYSLF ILGHLRTLMENQHWNHLIQDAQKRGAIIKTCDRNYKHDAMKILKLKPVLQRSLSHSPALA PEACRTPGGLPGSRPDSGLATSPFAPSLYHAPPDTRESIVPAKDAERSPAQDQLRDPRLL RRMGLAPETHLRDPQPPSPQHPGAALPSGEPGFPGSPQDLGGTVLLSTVRQACLAQCEPL ATGPEAAASKRKCEQRGGLSHRRETRALSDGAQDTYSAVSPPVNWGSGWDPRRVQEDSSS KKRKLL NT seq 7941 nt NT seq  +upstreamnt  +downstreamnt atgagcacatgctgctggtgtacgccaggtggtggttccaccgttgatttcctgaagtgc tatgcctccaagacccgctccagtgagtttcagaccgctgatgaagacctctgctactgc ttagagtgtgtggctgagtaccacagagcaagagagagcttgcagttcttgcacgaggtt ttatgggaattagaaaccttacgtctcataaatcactttgagaaatccatgaagggggaa attggagatgatgatgaattgtatatagtagacaacaatggggaggcacagctgtttgac ttcactggccaagactttgaaaacaagcttcgagttcctcttcttgaaatactgaaatat ccttatctacttttacatgaacgtgttaatgagttatgtgttgaagcactttgtcggatg gaacaagcgaattgctcttttcaggtttttgataaacatccagggatttatttgttcttg gtccatcccaatgaaatggttcgacggtgggctatcctgactgcaagaaacttaggaaaa gtggacagagatgattattatgacttgcaggaagtcttgacttgtcttttcaaggtcata gagttggggcttttagaaagtccggacatttatacttcttctgtcctcgagaagggtaaa ctgattcttcttccctcgcacatgtatgacactaccaactataaaaactactggctcggt atttgcatgttgctgaccattctcgaggagcaagccatggattcactgttgttgggctca gaaaagcaaaatgatttcatgcagtcaatacttcatactatggagagacaagtggatgat gatagtgtggaccctttctggccggcattacactgtttcatggtgattctggatcgcctt ggatctaaggtctggggtcaacttattgatcctatcgaggcctttcaaaccatcatcaac aatgtgagctacaacagagagatccagaatatacgaaacagctctgcacgggccaagtat gaaccggagtcatttttggatgacatggtgtcttgcagccagattgtgtacaactataac cccgaaaagaccaaaaaggattcggggtggagatcagccatttgcccagattactgtcct aacatgtatgaagagatggaaacattagccagcgtgcttcagtcagacattggtcaagac atgcgtgtccataacagcacgtttctgtggttcatccctttcgtccagtccctcatgggt ctgaaggacttgggtgtggcgtacatagcaggggtcatccatcatctccactcggaagtc aaggatgttctcaaccaaacggatgtcgtatgtgacaaagtgactgaattttttcttctg attttggtgtcagtgattgaactacacagaaataagaagtgtttgcatttgctgtgggtg acttcccagcagtgggtggaagccatcgtgaagtgcgccaagctccccaccactgcgttc gcacggagctcggagaagtcagctggaaactgctctaaggggtcggcggcggtggtgtcc tctctggcgctgcatgcggtgccgtccaactctgtgcagcttgcttgtgtgcagctgatc cggagtcttctcaaagagggctatcagcttgggcagcagacactttgtaagcgattctgg gataagctcaacttattcctgcgggggaatttatctctgggctggcagttgactagtcgg gaaaccctggaattacagacctgcttaaggcaaattatcaaaagcataaaagccaaggcc cctcaacactgtgcttatgtggatctgactcctgcgtgtaaaaaccctcctgcagtttac aaaaaagaaaaaaatgagcaaatagggaagaaatctaagaaacacgtgcactgtctggaa aactccagccccacattttctaaagaaccagtgaaaacagatgcatgtcaaatgcaagag actgtattggtcaaagcaactagcactatagtagaggataataagcaaagttatgtaaaa gattcaaagctacaagaccgtccctcagctgagctatccttgaagcagagcagtaaaaac caccacaccgagagagctccaggtgcagtcagaataagtacaaggaagcagaagtctgta aaagagaatccctcttacacgccaaagagtagtgttttgagaaatagtccagaaagggga tgtgacaagggaataatatcaacacattctttagctaattctagcaaaaaacctttggaa aagatggccacgtcaaatgaagacttcttaaaggatgatgctcgtggcaaaacctcagaa acaaaaatgaaggcacaaaaagatgatatctgtgctaagttatcacacgtaataaagaaa cagcaccggaaaagtactctggttggcagtgctatcaatttagaggaaaacctgactcac tcagacattgagagtttcttttcaaagaaagatgcagcaggtcagaaaggggatggcttt atacacaatccgggtttacaccctaatggtattctggatgataaaaatggagaacagaag tctcaaaacagtttgttgctgaaaaaacaattggagttaggtattttctcttcccatgat aacagcggtcaagttcaggactgccgtgttggtgataaagatctggcccctcttacagaa atgaccaatactttcttaaagaaaacatctccctttgaagatcctttgactgtgtttgaa aaaagagataaggaaagtgatcagagtgctgatcaggtttctcctgacttgagagagcag gcctctagcgccagtcctaagtctgacaccttaacggattcacaggtagacagagacctc cacaaattatctttaatagctcaagccagtgttattaaatttccttcagattcaactcaa aagagcttgtcccctctacaaggaaaagtgaaagatggttttgtaacgaaccagaacgct gttgcggaaggccgctgcggacaggttattattatttcagattctgatgatgacgacgag agaatgctgggttttgaaaaccgcattagacaagataaaatgtgcctagagaagcagtgt ctggggcagcgtgcttcgatctctgacacgcgagtggaaagggtgataaaggaagaagag actaaatctcttttgcagcttgaagaatctgattctcagatgtttgagtttgaaagtcaa aataaagtgttttcagtttggcaagatcaggaactggatgacaagcattcagctcaagag gatgaagaaaagtccggtctgacctgtaaacctgctgtcacaaaccagtgggcttatacc ggttacgcgtctgaagaggtcatggaaaaagagggcaccgaagaacgcgcagaagcacag agcgctagtatttctgttggggaattttgcaaagttgaagtaaaaaagccaaagagaaaa cgatttgacaaatctgtggaccaagatcctgtaaggtcttcctctgccaacgatgagtac caagctgatagtctcaatgagggagatctgactgaaaatgattttaaaattatcgacata aagactgtaactcccagctcaagtacggagagagccgccgcagctccgctaaagaggtct tctccaaagctgcgtagttactccagacccattaggagagtccgcgtctctaaacctaag aaaacacattcagataccaaaaaaggcccgaacagaaattccagttacctcacttgtagg acaactcctgctattgtgccgccaaagaaagctcgtcagtgtcctgaacctgcgtcaaca gccgagaaatttcgccttaaaaagggtcctcgcaaggcatttgagttgtctcagcggtct atggagtacatagtgcagttacgtgaccacggcaagaatgtgggagcagtggatatcaga aagaagactaagttaatctctcctcagactctctctgctaaaaataataagaaattgctg acaagtcaagatcttcagttgcgaaggcaggtgagacccaaatcacagcacagtagacaa gaactttttgataatggtaatgcagagccccgcgcagcccagagttatgacatgtttgca tcggactccggtgggtcagattataagcgaggagctaaagcagctgccaccagtaatgga aagcagttcatacaatgtgtgtcttctgagccagaacccatgagagcaaagcatgtttct gaggtgacccatgacacgtctctttcaaaccggtgtaattctgtggtgctaaatggaaga atcctggcgagtgaggcagcggcctctacttcagcgggccctgcaggtggaggcacccgc gccacacacttggccactcggaaagaaccagaacccgaggctggcagtgacatggaggac gatagtttgtttttaacacagaacgatcctgaagacatggatctgtgctcgcagatggag attgagccggcccaggggaaagatgccgttcaggtgggcacacatcctctcggccggcct caggtggagactccgagtagccggacgtctaagcacagagattgtaacgaagccgcaaga gcccatggcgacggctgcgcaacgcacgctgaggccagagccgcggatgaggatgtgttc cgtaagcctgccttgcccctgccgccctctaaacccctgaggccttccaggacgaagatt ttctgctgtacctcacgaagtgctaacctttccaggtctttggaaagcgacgccgcgctc ccaccagctctaaaaaccaagtccagcggggtgcagtccagcgtgaaggtgccccagcca gccttcctcgggcccccaaagccggtggcggaggtgaagagcctgtgcagcgtccttcct tctcagactccggccgccgccggcaggccgccctacaggcttccctttgctgaaagcaga tctttctccccggcctcttcaggcaacattctcttgccgtcgcagtccatctcggacgcc ttcgtgaaggaggtcttgaagtggaaatacgacatgtttgtgactttggatcagtttggg cctcccgcgagcctgtgtcattccgtctgcagaccggtgccggtcagatttcaagattat agagaatattttaatgtgtttttccctttgatgatactgaatacttttgaaacggtggcc caggaatggatcagttctccaaataaagagaaattctatcagttgcatgtccgaaaattt cctactgagtatgaaaaaagctgggagttggtggtttctcttgaggaatgtgaactggcc aagcagcttcatccaaaggaaaatgatttggtatttttggttcctgaaaaactaagtgga gagaagaaggatgcgaagagaaattgcatgcaagatccccatgagtattactgtggttat gtccacaaattccgccgcacttctgtcatgcgtaacgggaaatctgagtgttccctttcc atccagactcaagatactctgccagtcaacttaaatgaattggtgaaatgcattgtaatc agttctctggtaactacacaaaggaagttaagagccatgtctttgttgagtgatcagagc caactggccagagctgttctgaatccaaaccccatggacttcagtacaaaagatctgctg actacaacgtcagagagaattactgcctacttaagagatttcaacgaagaccagaagaag gcgatagagaccgcgtatgccatggtgaagcactccccggcggttgccaagatctgtctg attcatgggccacctggaacgggaaagtcgaaaaccatcgtcggcctcctgtaccgcctg ctgacagagacccagaggaggggacattcggatgagaactccaacgccaaaatcaaacag aaccgtgtcctcgtgtgtgcgccttccaacgcggctgttgatgaactgatgaaaaaaatt atcctcgaattcaaagaaaaatgtaaagacaagaagaatcctttaggaaactgcggagat ataaatttagtacgtctgggtccagaaaagtctattaacaatgaggtcctaaagttcagt ttggacagccaagtcaaccacaggatgaaaaaagacttaccttctcatgttcaggagatg cacagaagaaaggaatacctggatcttcagctggatgagctttcccgccagcgtgctcta tgccgggttggtagggagatgcagaagcaagaattagatgaaaaaattgccagcgtttca aaagaaaggcaggagcttgcttctaaaattaaagaggttcaaggacgcccccagaaaaca cagagcatcatcatcttggagtcccatgtcatctgctgcactctgagcaccagcggtggc ttgctgcttgagtctgcttttcgtaggcaaggaggtgtccccatcagctgtgtcattgtt gacgaggctgggcagtcttgtgaagtcgagactctcactccgctcatccatcgttgcaac aagctcatcctggtaggcgaccccaaacagctccctcccaccgtcatctccatgaaagcg caggagtatggctatgaccagtcgatgatggcgcgcttctgcaagctgctgggcgagaac gtggagcacgacgtgatgagcaggctgcccatcgtgcagctcaccacccagtaccgaatg caccccgatatctgcctcttcccttccaactacgtgtacaacagaaacctgaagaccaac agagtgactgagaccagtcggtgctcgtcagactggccattccagccttacctggtgttt gacgtgggagacggcgcagaaagacgggacaatgactcatatgtaaatgttcaagaaata aaactggtaatggaaataattaaacttattaaagacaaaaggagggatgtcactttccgg aacattggcatcatcacccattacaaggcccagaagaccatgattcagaaggatttggac agagagtttgacagaaaagggccagcagaagtggacactgtggatgcgttccaggggcgt cagaaagattgcgttattgttacgtgtgtcagagcaaatacttcgcaaggttccattggg tttctggcaagtttgcaaagattgaacgtcaccatcacgcgagccaagtacagcctcttc atccttgggcacctcaggaccctgatggaaaatcagcactggaatcacctgatacaagac gctcagaagcggggcgccatcatcaagacctgtgacaggaactataaacacgacgccatg aagatcctgaagctcaagcccgtcctgcagcggagtctgtcccactcgcctgccttggcc cccgaggcgtgcagaaccccaggcggcctgccgggcagcaggccagacagcgggctcgcc acgtcgcccttcgcgccctccctgtaccacgcccctcccgacaccagggagtccatcgtt cctgcaaaggatgccgagcggtcccccgcgcaggatcagcttcgggacccgcgactgctc aggagaatgggcctggctcccgagacacacctcagggacccgcagcccccgagcccccag caccctggagcagcgctgccatcgggagagcccggcttcccggggagcccccaggacctg ggcggcacggtgctgctgtccacagtcagacaggcctgtctggcgcagtgcgagcccctg gctactggccccgaggccgctgccagcaaaaggaagtgtgagcagcgaggagggctcagc cacaggagggagaccagggctctcagtgacggggcccaggacacatacagcgctgtgagc ccgcctgtgaactggggctctggctgggaccccaggagggtacaggaggacagtagctca aagaaaagaaagctgttatag

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